Increased endothelial nitric oxide synthase mRNA level in Bartter's and Gitelman's syndrome

Clinical Nephrology

Volumn 51, Issue 1, 1999, Pages 12-17

  Calo L ^b   Davis, P A ^a   Milani, M ^c   Cantaro, S ^c   Antonello, A ^c   Favaro, S ^c   D'Angelo, A ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF PADOVA   (Italy)

^c NONE

Author keywords

Bartter's syndrome; Gitelman's syndrome; Molecular biology; Nitric oxide; PCR; Vascular reactivity

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CHLORIDE ION; COMPLEMENTARY DNA; CYCLIC GMP; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNEL; SODIUM ION;

ADULT; ARTICLE; BARTTER SYNDROME; BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; FEMALE; GENE EXPRESSION; GENE MUTATION; GITELMAN SYNDROME; HUMAN; ION TRANSPORT; MALE; METABOLITE; MOLECULAR BIOLOGY; MONOCYTE; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; URINE LEVEL; VASCULAR RESISTANCE;

ADULT; BARTTER SYNDROME; CASE-CONTROL STUDIES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR RESISTANCE;

EID: 0032904289     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Asano K, Chee CBE, Gaston B et al 1994 Costitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci USA 91: 10089-10093
2. Bartter FC 1981 Bartter's syndrome: a disorder of vascular reactivity. Hypertension 3: 69-73
3. Bettinelli A, Bianchetti MG, Girardin E et al 1992 Use of calcium excretion values to distinguish two forms of primary renal tubular hypokalemic alkalosis: Bartter and Gitelman syndromes. J Pediatr 120: 8-43
4. Calò L, Cantaro S, Vianello A, Favaro S, Borsatti A 1986 Platelet calmodulin concentration in essential hypertension and in Bartter's syndrome. Am J Nephrol 6 (Suppl 1): 60-62
5. Calò L, Cantaro S, Piccoli A, Favaro S, Bonfante L, Borsatti A 1990 Full pattern of urinary prostaglandins in Bartter's syndrome. Nephron 56: 451-452
6. Calò L, Cantaro S, Calabro A et al 1995 Endothelium-derived vasoactive substances in Bartter's syndrome. Angiology 46: 905-913
7. Calò L, D'Angelo A, Cantaro S et al 1996a Intracellular calcium signalling and vascular reactivity in Bartter's syndrome. Nephron 72: 570-573
8. - and cyclic GMP levels in patients with Bartter's syndrome: relationship to vascular reactivity. Am J Kidney Dis 27: 874-879
9. Calò L, Davis PA, Milani M et al 1998 Constitutive endothelial nitric oxide synthase (ecNOS) gene expression in human monocytcs. Angiology in press.
10. Di Virgilio F, Calò L, Cantaro S et al 1987 Resting and stimulated cytosolic free calcium levels in neutrophils from patients with Bartter's syndrome. Clin Sci 72: 483-488
11. Marsden PA, Brenner BM 1991 Nitric oxide and endothelins: nouvel autocrine/paracrine regulators of the circulation. Seminars in Nephrol 11: 169-185
12. Marsden PA, Heng HHQ, Scherer SW et al 1993 Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 268: 17478-17488
13. Moncada S, Higgs A 1993 The L-Arginine-Nitric Oxide patway. N Engl J Med 329: 2002-2012
14. Reiling N, Ulmer AJ, Duchrow M et al 1994 Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages. Europ J Immunol 24: 1941-1944
15. Simon DB, Nelson-Williams C, Johnson Bia M et al 1996a Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter. Nature Genetics 12: 24-30
16. Simon DB, Karet FE, Hamdan JM et al 1996b Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2. Nature Genetics 13: 183-188
17. + channel. ROMK. Nature Genetics 14: 152-156
18. Simon DB, Bindra RS, Mansfield TA et al 1997 Mutation in the chloride channel gene CLCNKB, cause Bartter's syndrome type III. Nature Genetics 17: 171-179
19. Simon DB, Lifton RP 1996 The molecular basis of inherited hypokalemic alkalosis: Bartter's and Gitelman's syndromes. Am J Physiol 271: F961-F966
20. Stoos BA, Carretero OA, Farhy RD et al 1992 Endothelium derived relaxing factor inhibits transport and increases cGMP content in cultured mouse cortical collecting duct cells. J Clin Invest 89: 761-765