Gamma interferon production is critical for protective immunity to infection with blood-stage Plasmodium berghei XAT but neither NO production nor NK cell activation is critical

Infection and Immunity

Volumn 67, Issue 5, 1999, Pages 2349-2356

  Yoneto, Toshihiko ^a   Yoshimoto, Takayuki ^a   Wang, Chrong Reen ^a   Takahama, Yasuhiro ^a   Tsuji, Moriya ^b   Waki, Seiji ^c   Nariuchi, Hideo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b GUNMA PREFECTURAL COLLEGE OF HEALTH SCIENCES   (Japan)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRAGEENAN; CD4 ANTIGEN; GAMMA INTERFERON; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HOST RESISTANCE; INTERFERON INDUCTION; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PARASITE DEVELOPMENT; PARASITEMIA; PHAGOCYTOSIS; PLASMODIUM BERGHEI; PRIORITY JOURNAL; PROTOZOAL INFECTION; SPLEEN CELL;

EID: 0032903985     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.5.2349-2356.1999     Document Type: Article

References (46)

1. Bancroft, G. J. 1993. The role of natural killer cells in innate resistance to infection. Curr. Opin. Immunol. 5:503-510.
2. Brown, K. M., and J. P. Kreier. 1986. Effect of macrophage activation on phagocyte-plasmodium interaction. Infect. Immun. 51:744-749.
3. Buffinton, G. D., N. H. Hunt, W. B. Cowden, and I. A. Clark. 1988. Detection of short-chain carbonyl products of lipid peroxidation from malaria-parasite (Plasmodium vinckei)-infected red blood cells exposed to oxidative stress. Biochem. J. 249:63-68.
4. Cherwinski, H. M., J. H. Schumacher, K. D. Brown, and T. R. Mosmann. 1987. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J. Exp. Med. 166:1229-1244.
5. Clark, I. A., G. A. Butcher, G. D. Buffinton, N. H. Hunt, and W. B. Cowden. 1987. Toxicity of certain products of lipid peroxidation to the human malaria parasite Plasmodium falciparum. Biochem. Pharmacol. 36:543-546.
6. Clark, I. A., and K. A. Rockett. 1996. Nitric oxide and parasitic disease. Adv. Parasitol. 37:1-56.
7. Cot, S., P. Ringwald, B. Mulder, P. Miailhes, J. Yap Yap, A. K. Nussler, and W. M. Eling. 1994. Nitric oxide in cerebral malaria. J. Infect. Dis. 169:1417-1418.
8. De Souza, J. B., K. H. Williamson, T. Otani, and J. H. Playfair. 1997. Early gamma interferon responses in lethal and nonlethal murine blood-stage malaria. Infect. Immun. 65:1593-1598.
9. Eugul, E. M., and A. C. Allison. 1980. Differences in susceptibility of various mouse strains to haemoprotozoan infections: possible correlation with natural killer activity. Parasite Immunol. 2:277-292.
10. Goode, H. F., and N. R. Webster. 1993. Free radicals and antioxidants in sepsis. Crit. Care Med. 21:1770-1776.
11. Ishizaka, S., S. Otani, and S. Morisawa. 1978. Effect of carrageenan on immune responses. II. A possible regulatory role of macrophages in the immune responses of low-responder mice. J. Immunol. 120:61-65.
12. Jacobs, P., D. Radzioch, and M. M. Stevenson. 1995. Nitric oxide expression in the spleen, but not in the liver, correlates with resistance to blood-stage malaria in mice. J. Immunol. 155:5306-5313.
13. -/- mice. J. Immunol. 156:636-643.
14. Kitaguchi, T., M. Nagoya, T. Amano, M. Suzuki, and M. Minami. 1996. Analysis of roles of natural killer cells in defense against Plasmodium chabaudi in mice. Parasitol. Res. 82:352-357.
15. Laubach, V. E., E. G. Shesely, O. Smithies, and P. A. Sherman. 1995. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc. Natl. Acad. Sci. USA 92:10688-10692.
16. MacMicking, J., Q. W. Xie, and C. Nathan. 1997. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:323-350.
17. MacMicking, J. D., C. Nathan, G. Hom, N. Chartrain, D. S. Fletcher, M. Trumbauer, K. Stevens, Q. W. Xie, K. Sokol, and N. Hutchinson. 1995. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81:641-650.
18. MacMicking, J. D., R. J. North, R. LaCourse, J. S. Mudgett, S. K. Shah, and C. F. Nathan. 1997. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl. Acad. Sci. USA 94:5243-5248.
19. Mohan, K., P. Moulin, and M. M. Stevenson. 1997. Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection. J. Immunol. 159:4990-4998.
20. Nathan, C. 1995. Natural resistance and nitric oxide. Cell 82:873-876.
21. Nussler, A., J. C. Drapier, L. Renia, S. Pied, F. Miltgen, M. Gentilini, and D. Mazier. 1991. L-Arginine-dependent destruction of intrahepatic malaria parasites in response to tumor necrosis factor and/or interleukin 6 stimulation. Eur. J. Immunol. 21:227-230.
22. Nussler, A. K., W. Eling, and P. G. Kremsher. 1994. Patients with Plasmodium falciparum malaria and Plasmodium vivax malaria show increased nitrite and nitrate plasma levels. J. Infect. Dis. 169:1418-1419.
23. Orago, A. S., and C. A. Facer. 1991. Cytotoxicity of human natural killer (NK) cell subsets for Plasmodium falciparum erythrocytic schizonts: stimulation by cytokines and inhibition by neomycin. Clin. Exp. Immunol. 86:22-29.
24. Oswald, I. P., I. Eltoum, T. A. Wynn, B. Schwartz, P. Caspar, D. Paulin, A. Sher, and S. L. James. 1994. Endothelial cells are activated by cytokine treatment to kill an intravascular parasite, Schistosoma mansoni, through the production of nitric oxide. Proc. Natl. Acad. Sci. USA 91:999-1003.
25. Picard, S., S. Parthasarathy, J. Fruebis, and J. L. Witztum. 1992. Amino-guanidine inhibits oxidative modification of low density lipoprotein protein and the subsequent increase in uptake by macrophage scavenger receptors. Proc. Natl. Acad. Sci. USA 89:6876-6880.
26. + cells but markedly decreased helper cell activity in mice lacking CD4. Nature 353: 180-184.
27. Rao, U. R., A. C. Vickery, B. H. Kwa, J. K. Nayar, and D. Subrahmanyam. 1992. Effect of carrageenan on the resistance of congenially athymic nude and normal BALB/c mice to infective larvae of Brugia malayi. Parasitol. Res. 78:235-240.
28. Rockett, K. A., M. M. Awburn, W. B. Cowden, and I. A. Clark. 1991. Killing of Plasmodium falciparum in vitro by nitric oxide derivatives. Infect. Immun. 59:3280-3283.
29. Scharton Kersten, T. M., G. Yap, J. Magram, and A. Sher. 1997. Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J. Exp. Med. 185:1261-1273.
30. Sedegah, M., F. Finkelman, and S. L. Hoffman. 1994. Interleukin 12 induction of interferon-γ-dependent protection against malaria. Proc. Natl. Acad. Sci. USA 91:10700-10702.
31. + T cells. J. Exp. Med. 180:353-358.
32. Shear, H. L., R. S. Nussenzweig, and C. Blanco. 1979. Immune phagocytosis in murine malaria. J. Exp. Med. 149:1288-1298.
33. Skamene, E., M. M. Stevenson, and S. Lemieux. 1983. Murine malaria: dissociation of natural killer (NK) cell activity and resistance to Plasmodium chabaudi. Parasite Immunol. 5:557-565.
34. Solomon, J. B. 1986. Natural cytotoxicity for Plasmodium berghei in vitro by spleen cells from susceptible and resistant rats. Immunology 59:277-281.
35. Stevenson, M. M., E. Ghadirian, N. C. Phillips, D. Rae, and I. E. Podoba. 1989. Role of mononuclear phagocytes in elimination of Plasmodium chabaudi AS infection. Parasite Immunol. 11:529-544.
36. Stevenson, M. M., M. F. Tam, S. F. Wolf, and A. Sher. 1995. IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism. J. Immunol. 155:2545-2556.
37. Stuehr, D. J., and M. A. Marletta. 1985. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA 82:7738-7742.
38. Taylor Robinson, A. W., R. S. Phillips, A. Severn, S. Moncada, and F. Y. Liew. 1993. The role of TH1 and TH2 cells in a rodent malaria infection. Science 260:1931-1934.
39. Theander, T. G., B. K. Pedersen, I. C. Bygbjerg, S. Jepsen, P. B. Larsen, and A. Kharazmi. 1987. Enhancement of human natural cytotoxicity by Plasmodium falciparum antigen activated lymphocytes. Acta Trop. 44:415-422.
40. Vidal, S., M. L. Tremblay, G. Govoni, S. Gaouthin, G. Sebastioni, D. Malo, E. Skamene, M. Olivier, S. Jothy, and P. Gras. 1995. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J. Exp. Med. 182:655-666.
41. Waki, S., J. Tamura, M. Imanaka, S. Ishikawa, and M. Suzuki. 1982. Plasmodium berghei: isolation and maintenance of an irradiation attenuated strain in the nude mouse. Exp. Parasitol. 53:335-340.
42. Waki, S., S. Uehara, K. Kanbe, H. Nariuchi, and M. Suzuki. 1995. Interferon-γ and the induction of protective IgG2a antibodies in non-lethal Plasmodium berghei infections of mice. Parasite Immunol. 17:503-508.
43. Waki, S., S. Uehara, K. Kanbe, K. Ono, M. Suzuki, and H. Nariuchi. 1992. The role of T cells in pathogenesis and protective immunity to murine malaria. Immunology 75:646-651.
44. Wei, X. Q., I. G. Charles, A. Smith, J. Ure, G. J. Feng, F. P. Huang, D. Xu, W. Muller, S. Moncada, and F. Y. Liew. 1995. Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 375:408-411.
45. Wood, P. R., and I. A. Clark. 1982. Apparent irrelevance of NK cells to resolution of infections with Babesia microti and Plasmodium vinckei petteri in mice. Parasite Immunol. 4:319-327.
46. Yoshimoto, T., T. Yoneto, S. Waki, and H. Nariuchi. 1998. Interleukin-12-dependent mechanisms in the clearance of blood-stage murine malaria parasite Plasmodium berghei XAT, an attenuated variant of P. berghei NK65. J. Infect. Dis. 177:1674-1681.