-
1
-
-
0020264035
-
Synthesis of (15)-deoxyspergualin and (-)-spergualin-15-phosphate
-
IWASAWA, H.; S. KONDO, D. IKEDA, T. TAKEUCHI & H. UMEZAWA: Synthesis of (15)-deoxyspergualin and (-)-spergualin-15-phosphate. J. Antibiotics 35: 1665-1669, 1982
-
(1982)
J. Antibiotics
, vol.35
, pp. 1665-1669
-
-
Iwasawa, H.1
Kondo, S.2
Ikeda, D.3
Takeuchi, T.4
Umezawa, H.5
-
2
-
-
0019769255
-
A new antitumor antibiotic, spergualin. Isolation and antitumor activity
-
TAKEUCHI, T.; H. IINUMA, S. KUNIMOTO, T. MASUDA, M. ISHIZUKA, M. TAKEUCHI, M. HAMADA, H. NAGANAWA, S. KONDO & H. UMEZAWA: A new antitumor antibiotic, spergualin. Isolation and antitumor activity. J. Antibiotics 34: 1619-1621, 1981
-
(1981)
J. Antibiotics
, vol.34
, pp. 1619-1621
-
-
Takeuchi, T.1
Iinuma, H.2
Kunimoto, S.3
Masuda, T.4
Ishizuka, M.5
Takeuchi, M.6
Hamada, M.7
Naganawa, H.8
Kondo, S.9
Umezawa, H.10
-
3
-
-
0023630524
-
Immunosuppressive activity of 15-deoxyspergualin and its effect on skin alografts in rats
-
MASUDA, T.; S. MIZUTANI, M. IIJIMA, H. ODAI, H. SUDA, M. ISHIZUKA, T. TAKEUCHI & H. UMEZAWA: Immunosuppressive activity of 15-deoxyspergualin and its effect on skin alografts in rats. J. Antibiotics 40: 1612-1618, 1987
-
(1987)
J. Antibiotics
, vol.40
, pp. 1612-1618
-
-
Masuda, T.1
Mizutani, S.2
Iijima, M.3
Odai, H.4
Suda, H.5
Ishizuka, M.6
Takeuchi, T.7
Umezawa, H.8
-
4
-
-
0023202863
-
Immunosuppressive activities of 15-deoxyspergualin in animals
-
NEMOTO, H.; M. HAYASHI, F. ABE, T. NAKAMURA, M. ISHIZUKA & H. UMEZAWA: Immunosuppressive activities of 15-deoxyspergualin in animals. J. Antibiotics 40: 561-562, 1987
-
(1987)
J. Antibiotics
, vol.40
, pp. 561-562
-
-
Nemoto, H.1
Hayashi, M.2
Abe, F.3
Nakamura, T.4
Ishizuka, M.5
Umezawa, H.6
-
5
-
-
0023628475
-
Immunosuppressive activities of deoxyspergualin. II. The effect on the antibody responses
-
MAKINO, M.; M. FUJIWARA, H. WATANABE, T. AOYAGI & H. UMEZAWA: Immunosuppressive activities of deoxyspergualin. II. The effect on the antibody responses. Immunopharamcology 14: 115-122, 1987
-
(1987)
Immunopharamcology
, vol.14
, pp. 115-122
-
-
Makino, M.1
Fujiwara, M.2
Watanabe, H.3
Aoyagi, T.4
Umezawa, H.5
-
6
-
-
0023790646
-
In vivo effects of deoxyspergualin (NKT-01) on lymphocyte activation in response to alloantigens
-
YOSHIKAWA, Y.; H. UCHIDA, H. KURODA, T. NAKAMURA, A. OBAYASHI, A. FUJII & T. TAKEUCHI: In vivo effects of deoxyspergualin (NKT-01) on lymphocyte activation in response to alloantigens. J. Antibiotics 41: 1675-1680, 1988
-
(1988)
J. Antibiotics
, vol.41
, pp. 1675-1680
-
-
Yoshikawa, Y.1
Uchida, H.2
Kuroda, H.3
Nakamura, T.4
Obayashi, A.5
Fujii, A.6
Takeuchi, T.7
-
8
-
-
0028277737
-
In vivo radiation by nitric oxide modulation
-
LIEBMANN, J.; A. N. DELUCA, D. COFFIN, L. L. KEEFER, D. VENZON, D. A. WINK & J. B. MITCHELL: In vivo radiation by nitric oxide modulation. Cancer Research 54: 3365-3368, 1994
-
(1994)
Cancer Research
, vol.54
, pp. 3365-3368
-
-
Liebmann, J.1
Deluca, A.N.2
Coffin, D.3
Keefer, L.L.4
Venzon, D.5
Wink, D.A.6
Mitchell, J.B.7
-
9
-
-
0028659788
-
G-nitro-L-arginine
-
G-nitro-L-arginine. Cancer Research 54: 6458-6463, 1994
-
(1994)
Cancer Research
, vol.54
, pp. 6458-6463
-
-
Wood, P.J.1
Sansom, J.M.2
Butler, S.A.3
Stratford, I.J.4
Cole, S.M.5
Szabo, C.6
Thiemermann, C.7
Adams, G.E.8
-
10
-
-
0024950067
-
Basic studies on spergualins
-
Ed. T. TAKEUCHI, K. NITTA & N. TANAKA, Japan Scientific Societies Press, Tokyo
-
KUNIMOTO, S.; M. ISHIZUKA, H. IINUMA & T. TAKEUCHI: Basic studies on spergualins, in Gann Monograph on Cancer Research No. 36, "Antitumor natural products" Ed. T. TAKEUCHI, K. NITTA & N. TANAKA, pp. 179-191, Japan Scientific Societies Press, Tokyo, 1989
-
(1989)
Gann Monograph on Cancer Research No. 36,"Antitumor Natural Products"
, vol.36
, pp. 179-191
-
-
Kunimoto, S.1
Ishizuka, M.2
Iinuma, H.3
Takeuchi, T.4
-
11
-
-
0028174061
-
Function and activation of NF-κB in the immune system
-
BAEUERLE, P. A. & T. HENKEL: Function and activation of NF-κB in the immune system. Annu. Rev. Immunology 12: 149-179, 1994
-
(1994)
Annu. Rev. Immunology
, vol.12
, pp. 149-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
12
-
-
0028823207
-
Rat Kupffer cell-derived nitric oxide modulates induction of lymphokine-activated killer cell
-
KUROSE, I.; S. MIURA, H. SAITO, S. TADA, D. FUKUMURA, H. HIGUCHI & H. ISHII: Rat Kupffer cell-derived nitric oxide modulates induction of lymphokine-activated killer cell. Gastroenterology 109: 1958-1968, 1995
-
(1995)
Gastroenterology
, vol.109
, pp. 1958-1968
-
-
Kurose, I.1
Miura, S.2
Saito, H.3
Tada, S.4
Fukumura, D.5
Higuchi, H.6
Ishii, H.7
-
14
-
-
0026360175
-
Complexes of · NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects
-
MARAGOS, C. A.; D. MORLEY, D. A. WINK, T. M. DUNAMS, J. E. SAAVEDRA, A. HOFFMAN, A. A. BOVE, L. ISAAC, J. A. HRABIE & L. K. KEEFER: Complexes of · NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. J. Medicinal Chemistry 34: 3242-3247, 1991
-
(1991)
J. Medicinal Chemistry
, vol.34
, pp. 3242-3247
-
-
Maragos, C.A.1
Morley, D.2
Wink, D.A.3
Dunams, T.M.4
Saavedra, J.E.5
Hoffman, A.6
Bove, A.A.7
Isaac, L.8
Hrabie, J.A.9
Keefer, L.K.10
-
15
-
-
0019841289
-
Structure of an antitumor antibiotic, spergualin
-
UMEZAWA, H.; S. KONDO, H. IINUMA, S. KUNIMOTO, Y. IKEDA, H. IWASAWA, D. IKEDA & T. TAKEUCHI: Structure of an antitumor antibiotic, spergualin. J. Antibiotics 34: 1622-1624, 1981
-
(1981)
J. Antibiotics
, vol.34
, pp. 1622-1624
-
-
Umezawa, H.1
Kondo, S.2
Iinuma, H.3
Kunimoto, S.4
Ikeda, Y.5
Iwasawa, H.6
Ikeda, D.7
Takeuchi, T.8
-
16
-
-
0027527363
-
A fluorometric assay for the measurement of nitrite in biological samples
-
MISKO, T. S.; R. J. SCHELLING, D. SALVEMINI, W. M. MOORE & M. G. CURRIE: A fluorometric assay for the measurement of nitrite in biological samples. Analytical Biochemistry 214: 11-16, 1993
-
(1993)
Analytical Biochemistry
, vol.214
, pp. 11-16
-
-
Misko, T.S.1
Schelling, R.J.2
Salvemini, D.3
Moore, W.M.4
Currie, M.G.5
-
17
-
-
0003323995
-
Analysis of proteins
-
John Wiley & Sons, Inc., New York
-
Analysis of Proteins, in Current Protocols in Molecular Biology Vol. 3, Eds. F. M. AUSUBEL, R. BRENT, R. E. KINGSTON, D. D. MOORE, J. G. SEIDMAN, J. A. SMITH & K. STRUHL, John Wiley & Sons, Inc., New York, 1996
-
(1996)
Current Protocols in Molecular Biology
, vol.3
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
18
-
-
0029786784
-
15-Deoxyspergualin: A newly developed immunosuppressive agent and its mechanism of action and clinical effect: A review. Japan collaborative transplant study group for NKT-01
-
AMEMIYA, H.: 15-Deoxyspergualin: a newly developed immunosuppressive agent and its mechanism of action and clinical effect: a review. Japan Collaborative transplant study group for NKT-01. Artif Organs 20: 832-835, 1996
-
(1996)
Artif Organs
, vol.20
, pp. 832-835
-
-
Amemiya, H.1
-
19
-
-
0025781323
-
Inhibition of angiogenesis by 15-deoxyspergualin
-
OIKAWA, T.; M. SHIMAMURA, H. ASHINO-FUSE, T. IWAGUCHI, M. ISHIZUKA & T. TAKEUCHI: Inhibition of angiogenesis by 15-deoxyspergualin. J. Antibiotics 44: 1033-1035, 1991
-
(1991)
J. Antibiotics
, vol.44
, pp. 1033-1035
-
-
Oikawa, T.1
Shimamura, M.2
Ashino-Fuse, H.3
Iwaguchi, T.4
Ishizuka, M.5
Takeuchi, T.6
-
20
-
-
0026466177
-
Anti-angiogenic effect of 15-deoxyspergualin in angiogenesis model system involving human microvascular endothelial cell
-
KIUE, H.; T. ABE, A. MORIMOTO, K. OKAMURA, M. ONO, K. KHONO, T. OIKAWA, T. IWAGUCHI, M. ISHIZUKA, T. TAKEUCHI & M. KUWANO: Anti-angiogenic effect of 15-deoxyspergualin in angiogenesis model system involving human microvascular endothelial cell. Cancer J. 5: 267-271, 1992
-
(1992)
Cancer J.
, vol.5
, pp. 267-271
-
-
Kiue, H.1
Abe, T.2
Morimoto, A.3
Okamura, K.4
Ono, M.5
Khono, K.6
Oikawa, T.7
Iwaguchi, T.8
Ishizuka, M.9
Takeuchi, T.10
Kuwano, M.11
-
21
-
-
0026526303
-
Interaction of the immunosuppressant deoxyspergualin with a member of the Hsp70 family of heat shock proteins
-
NADLER, S. G.; M. A. TEPPER, B. SCHACTER & C. E. MAZZUCCO: Interaction of the immunosuppressant deoxyspergualin with a member of the Hsp70 family of heat shock proteins. Science 258: 484-486, 1992
-
(1992)
Science
, vol.258
, pp. 484-486
-
-
Nadler, S.G.1
Tepper, M.A.2
Schacter, B.3
Mazzucco, C.E.4
-
22
-
-
0028230782
-
Quantitation of the interaction the immunosuppressant deoxyspergualin and analogs with Hsc70 and Hsp90
-
NADEAU, K.; S. G. NADLER, M. SAULNIER, M. A. TEPPER & C. T. WALSH: Quantitation of the interaction the immunosuppressant deoxyspergualin and analogs with Hsc70 and Hsp90. Biochemistry 33: 2561-2567, 1994
-
(1994)
Biochemistry
, vol.33
, pp. 2561-2567
-
-
Nadeau, K.1
Nadler, S.G.2
Saulnier, M.3
Tepper, M.A.4
Walsh, C.T.5
-
23
-
-
0028895152
-
Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin
-
NADLER, S. G.; C. B. ASHLEY, C. B. EVERSOLE, M. A. TEPPER & J. S. CLEAVELAND: Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin. Therapeutic Drug Monitoring 17: 700-703, 1995
-
(1995)
Therapeutic Drug Monitoring
, vol.17
, pp. 700-703
-
-
Nadler, S.G.1
Ashley, C.B.2
Eversole, C.B.3
Tepper, M.A.4
Cleaveland, J.S.5
-
24
-
-
0028029788
-
Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes
-
HOEGER, P. H.; M. A. TEPPER, A. FAITH, J. A. HIGGINS, J. R. LAMB & R. F. GEHA: Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes. J. Immunology 153: 3908-3916, 1994
-
(1994)
J. Immunology
, vol.153
, pp. 3908-3916
-
-
Hoeger, P.H.1
Tepper, M.A.2
Faith, A.3
Higgins, J.A.4
Lamb, J.R.5
Geha, R.F.6
-
25
-
-
0026495863
-
Expression and characterization of human FKB52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes
-
PEATTIE, D. A.; HARDING, M. W., FLEMING, M. A., DECENZO, M. T., LIPPKE, J. A., LIVINSTON, D. J. & BENASUTTI, M: Expression and characterization of human FKB52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. Proc. Natl. Acad. Sci. USA 89: 10974-10978, 1992
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10974-10978
-
-
Peattie, D.A.1
Harding, M.W.2
Fleming, M.A.3
Decenzo, M.T.4
Lippke, J.A.5
Livinston, D.J.6
Benasutti, M.7
-
26
-
-
0026657636
-
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13
-
YEM, A. W.; A. G. TOMASSELLI, R. L. HEINRIKSON, H. ZURCHER-NEELY, V. A. RUFF, R. A. JOHNSON & M. R. DEIBRL, Jr.: The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. J. Biol. Chem. 267: 2868-2871, 1992
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2868-2871
-
-
Yem, A.W.1
Tomasselli, A.G.2
Heinrikson, R.L.3
Zurcher-Neely, H.4
Ruff, V.A.5
Johnson, R.A.6
Deibrl M.R., Jr.7
-
27
-
-
0029101382
-
The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic hetero-complexes with the untransformed glucocorticoid receptor
-
OWENS-GRILLO, J. K.; K. HOFFMANN, K. A. HUTCHISON, A. W. YEM, M. R. DEIBEL, Jr., R. E. HANDSCHUMACHER & W. B. PRATT: The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic hetero-complexes with the untransformed glucocorticoid receptor. J. Biol. Chem. 270: 20479-20484, 1995
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20479-20484
-
-
Owens-Grillo, J.K.1
Hoffmann, K.2
Hutchison, K.A.3
Yem, A.W.4
Deibel M.R., Jr.5
Handschumacher, R.E.6
Pratt, W.B.7
-
28
-
-
0345505069
-
Biochemical mechanism of deoxyspergualin
-
Nihon Igakukan, Inc., Tokyo, in Japanese
-
OHINATA, A.: Biochemical mechanism of deoxyspergualin. In Deoxyspergualin: A new immunosuppressive agent. Ed. H. AMEMIYA, pp. 41-44 Nihon Igakukan, Inc., Tokyo, 1994 (in Japanese)
-
(1994)
Deoxyspergualin: A New Immunosuppressive Agent
, pp. 41-44
-
-
Ohinata, A.1
Amemiya, H.2
-
29
-
-
0029111410
-
Simultaneous evaluation of nitric oxide synthesis and tissue oxygenation in rat liver allograft rejection using near-infrared spectroscopy
-
ORDAN, H.; Y. FUKUDA, S. SUZUKI, H. AMEMIYA & K. DOHI: Simultaneous evaluation of nitric oxide synthesis and tissue oxygenation in rat liver allograft rejection using near-infrared spectroscopy. Transplantation 60: 530-535, 1995
-
(1995)
Transplantation
, vol.60
, pp. 530-535
-
-
Ordan, H.1
Fukuda, Y.2
Suzuki, S.3
Amemiya, H.4
Dohi, K.5
-
30
-
-
0027096817
-
Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine
-
ROGERS, N. E. & L. J. IGNARRO: Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine. Biochem. Biophys. Res. Commun. 189: 242-249, 1992
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 242-249
-
-
Rogers, N.E.1
Ignarro, L.J.2
-
31
-
-
0027374973
-
Inducible nitric oxide synthase from a rat alveolar macrophage cell line is inhibited by nitric oxide
-
GRISCAVAGE, J. M.; N. E. ROGERS, M. P. SHERMAN & L. J. IGNARRO: Inducible nitric oxide synthase from a rat alveolar macrophage cell line is inhibited by nitric oxide. J. Immunology 151: 6329-6337, 1993
-
(1993)
J. Immunology
, vol.151
, pp. 6329-6337
-
-
Griscavage, J.M.1
Rogers, N.E.2
Sherman, M.P.3
Ignarro, L.J.4
|