Mice deficient in the urea-cycle enzyme, carbamoyl phosphate synthetase I, die during the early neonatal period from hyperammonemia

Hepatology

Volumn 29, Issue 1, 1999, Pages 181-185

  Schofield, J Paul ^a,d   Cox, Timothy M ^a   Caskey, C Thomas ^b   Wakamiya, Maki ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMOYL PHOSPHATE SYNTHASE;

AMINO ACID METABOLISM; AMMONIA BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATABOLISM; CONTROLLED STUDY; ENZYME DEFICIENCY; ENZYME DEGRADATION; ENZYME LOCALIZATION; HYPERAMMONEMIA; INBORN ERROR OF METABOLISM; MITOCHONDRIAL MEMBRANE; MOUSE; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; UREA CYCLE;

AMINO ACID SEQUENCE; AMMONIA; ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; BRAIN; CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA); DISEASE MODELS, ANIMAL; GENE TARGETING; GENETIC VECTORS; GENOTYPE; LIVER; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; UREA;

EID: 0032902675     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510290112     Document Type: Article

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