Influence of age and strain on striatal dopamine loss in a genetic mouse model of Lesch-Nyhan disease

Journal of Neurochemistry

Volumn 72, Issue 1, 1999, Pages 225-229

  Jinnah, H A ^a   Jones, M D ^b   Wojcik, B E ^c   Rothstein, J D ^a   Hess, E J ^b   Friedmann, T ^c   Breese, G R ^d  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Basal ganglia; Dopamine; Hypoxanthine guanine phosphoribosyltransferase; Knockout; Lesch Nyhan disease; Striatum

Indexed keywords

AMINO ACID DECARBOXYLASE; AROMATIC AMINO ACID; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINE METABOLISM; ENZYME ACTIVITY; ENZYME DEFICIENCY; GENE MUTATION; GENETIC MODEL; KNOCKOUT MOUSE; LESCH NYHAN SYNDROME; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AGE FACTORS; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; BEHAVIOR, ANIMAL; CHOLINE O-ACETYLTRANSFERASE; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DOPAMINE; FEMALE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LESCH-NYHAN SYNDROME; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; NEOSTRIATUM; SPECIES SPECIFICITY; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 0032901230     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0720225.x     Document Type: Article

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