Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 11, 1996, Pages 5539-5543

  Wong, Dean F ^a,g   Harris, James C ^a   Naidu, Sakkubai ^a,b   Yokoi, Fuji ^a   Marenco, Stefano ^a   Dannals, Robert F ^a   Ravert, Hayden T ^a   Yaster, Myron ^a   Evans, Alan ^c   Rousset, Olivier ^c   Bryan, R Nick ^a   Gjedde, Albert ^d   Kuhar, Michael J ^e   Breese, George R ^f  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d AARHUS UNIVERSITY HOSPITAL   (Denmark)

^e EMORY UNIVERSITY   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

mental retardation; neurodevelopment; positron emission tomography; Rett syndrome

Indexed keywords

CARRIER PROTEIN; DOPAMINE;

ADULT; ARTICLE; BRAIN MAPPING; CAUDATE NUCLEUS; CELL DENSITY; CLINICAL ARTICLE; DISEASE ASSOCIATION; DOPAMINE BRAIN LEVEL; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; HUMAN; LESCH NYHAN SYNDROME; PATHOGENESIS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PUTAMEN; RETT SYNDROME;

ADOLESCENT; ADULT; BRAIN; CARBON RADIOISOTOPES; CARRIER PROTEINS; CEREBELLUM; COCAINE; CORPUS STRIATUM; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; HUMANS; KINETICS; LESCH-NYHAN SYNDROME; MAGNETIC RESONANCE IMAGING; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; PUTAMEN; REFERENCE VALUES; RETT SYNDROME; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 9344268249     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.11.5539     Document Type: Article

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