Thrombin: A novel renal growth factor

Experimental Nephrology

Volumn 7, Issue 1, 1999, Pages 20-25

  Grandaliano, Giuseppe ^a   Gesualdo, Loreto ^b   Schena, Francesco P ^b  

^a UNIVERSITY OF BARI   (Italy)

^b NONE

Author keywords

Coagulation factors; Glomerulonephritis; Protease activated receptors; Thrombin

Indexed keywords

BLOOD CLOTTING FACTOR; GROWTH FACTOR; PROTEINASE; THROMBIN;

ANIMAL CELL; BLOOD CLOTTING; CELL FUNCTION; CELL PROLIFERATION; DRUG RECEPTOR BINDING; EXTRACELLULAR MATRIX; FIBRIN CLOT; GLOMERULONEPHRITIS; GLOMERULOPATHY; HISTOPATHOLOGY; KIDNEY DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SHORT SURVEY;

EID: 0032900165     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: 10.1159/000020580     Document Type: Short Survey

References (47)

1. Glassock RJ, Adler SG, Ward HJ: Primary glomerular diseases; in Brenner BM, Rector FC (eds): The Kidney. Philadelphia, Saunder, 1991, vol I, pp 1182-1279.
2. Kincaid-Smith P: Coagulation and renal disease. Kidney Int 1972;2:183-190.
3. Mann KG, Lundblad RL: Biochemistry of thrombin; in Colman R, Hirsh J, Marder V, Salzman E (eds): Homeostasis and Thrombosis. Philadelphia, Lippincott. 1987, pp 148-161.
4. Wilner GD, Danitz MP, Mudd MS, Hsieh K-H, Fenton JW: Selective immobilization of a-thrombin by surface-bound fibrin. J Lab Clin Med 1980;97:403-411.
5. Shuman MA: Thrombin-cellular interaction. Ann NY Acad Sci 1986;485:228-239.
6. Grand RJA, Turnell AS, Grabham PW: Cellular consequences of thrombin receptor activation. Biochem J 1996;313:353-368.
7. Van Obberghen-Schilling E, Pouyssegur J: Signaling pathways of the thrombin receptor. Thromb Haemost 1993;70:163-168.
8. Vu TK, Hung DT, Wheaton VI, Coughlin SR: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991;64:1057-1068.
9. Chen J, Ishii, M, Wang L, Ishii K, Coughlin SR: Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode. J Biol Chem 1994; 269:16041-16045.
10. Hexie JA, Ahuja M, Belmonte E, Pizarro S, Parton R, Brass LF: Internalization and recycling of activated thrombin receptors. J Biol Chem 1993;268:13756-13763.
11. Furman MI, Liu L, Benoit SE, Becker RC, Barnard MR, Michelson AD: The cleaved peptide of the thrombin receptor is a strong platelet agonist. Proc Natl Acad Sci USA 1998;95: 3032-3087.
12. Connolly A, Ishihara H, Kahn M, Farese RV, Coughlin SR: Role of the thrombin receptor in development and evidence for a second receptor. Nature 1996;381:516-519.
13. Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR: Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 1997; 386:502-506.
14. Xu Wf, Andersen H, Whitmore TE, Presnell SR, Yee DP, Ching A, Gilbert T, Davie EW, Foster DC: Cloning and characterization of human protease-activated receptor 4. Proc Natl Acad Sci USA 1998;95:6642-6646.
15. Grandaliano G, Valente AJ, Abboud HE: A novel biologic activity of thrombin: Stimulation of monocyte chemotactic protein production. J Exp Med 1994;179:1737-1741.
16. Xu Y, Zacharias U, Peraldi MN, He CJ, Lu C, Sraer JD, Brass LF, Rondeau E: Constitutive expression and modulation of the functional thrombin receptor in the human kidney. Am J Pathol 1995;146:101-110.
17. Zacharias U, Xu Y, Hagege J, Sraer JD, Brass LF, Rondeau E: Thrombin, phorbol ester, and cAMP regulate thrombin receptor protein and mRNA expression by different pathways. J Biol Chem 1995;270:545-550.
18. Nystedt S, Ramakrishnan V, Sundelin J: The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J Biol Chem 1996;271:14910-14915.
19. Wilcox JN, Roclriguez J, Subramanian R, Ollerenshaw J, Zhong C, Hayzer DJ, Horaist C, Hanson SR, Lumsden A, Salam TA: Characterization of thrombin receptor expression during vascular lesion formation. Circ Res 1994;75: 1029-1038.
20. Li F, Baykal D, Horaist C, Yan CN, Carr BN, Rao GN, Runge MS: Cloning and identification of regulatory sequences of the human thrombin receptor gene. J Biol Chem 1996; 271:26320-26328.
21. Abboud HE: Growth factors in glomerulonephritis. Kidney Int 1993;43:252-267.
22. Hung DT, Wong YH, Vu TK, Coughlin SR: The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase. J Biol Chem 1992;267:20831-20834.
23. Biswas P, Abboud HE, Kiyomoto H, Wenzel UO, Grandaliano G, Choudhury GG: PKC alpha regulates thrombin-induced PDGF-B chain gene expression in mesangial cells. FEBS Lett 1995;373:146-150.
24. Choudhury GG, Marra F, Abboud HE: Thrombin stimulates association of src homology domain containing adaptor protein Nek with pp125FAK. Am J Physiol 1996;270: F295-F300.
25. Delafontaine P, Anwar A, Lou H, Ku L: G-protein coupled and tyrosine kinase receptors: Evidence that activation of IGF-1 receptor is required for thrombin-induced mitogenesis of rat aortic smooth muscle cells. J Clin Invest 1996; 97:139-145.
26. Daub H, Wallasch C, Lankenau A, Herrlich A, Ullrich A: Signal characteristics of G protein-transactivated EGF receptor. EMBO J 1997; 16:7032-7044.
27. Grandaliano G, Choudhury GG, Biswas P, Abboud HE: Mitogenic signaling of thrombin in mesangial cells: Role of tyrosine phosphorylation. Am J Physiol 1994;267:F528-F536.
28. Floege J, Burns MW, Alpers CE, Yoshimura A, Pritzl P, Gordon K, Seifert SA, Bowen-Pope DF, Couser W, Johnson RJ: Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int 1992;41:297-309.
29. Grandaliano G, Poptic E, Barnes JL, Choudhury GG, Woodruff K, Abboud HE: Thrombin stimulates platelet-derived growth factor production in cultured bovine glomerular endothelial cells. J Am Soc Nephrol 1998;9:583-589.
30. Shultz PJ, Knauss TC, Mené P, Abboud HE: Mitogenic signals for thrombin in mesangial cells: Regulation of phospholipase C and PDGF genes. Am J Physiol 1989;257:F366-F374.
31. He CJ, Peraldi MN, Adida C, Rebibou JM, Meulders Q, Sraer JD, Rondeau E: Thrombin signal transduction mechanisms in human glomerular epithelial cells. J Cell Physiol 1992; 150;475-483.
32. Schwartz SM: Serum-derived growth factor is thrombin? J Clin Invest 1993;91:4.
33. Weiss RH, Maduri M: The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor. J Biol Chem 1993;268:5724-5727.
34. Zoja C, Orisio S, Perico N, Benigni A, Morigi M, Benatti L, Rambaldi A, Remuzzi G: Constitutive expression of endothelin gene in cultured human mesangial cells and its modulation by transforming growth factor-beta, thrombin, and a thromboxane A2 analogue. Lab Invest 1991;64:16-20.
35. Armstrong MT, Fenton JW, Andersen TT, Armstrong PB: Thrombin stimulation of matrix fibronectin. J Cell Physiol 1996;166:112-120.
36. Papadimitriou E, Manolopoulos VG, Hayman GT, Maragoudakis ME, Unsworth BR, Fenton JW, Lelkes PI: Thrombin modulates vectorial secretion of extracellular matrix proteins in cultured endothelial cells. Am J Physiol 1997;272: C1112-C1122.
37. Yamabe H, Osawa H, Inuma H, Kaizuka M, Tamura N, Tsunoda S, Baba Y, Shirato K, Onodera K: Thrombin stimulates production of transforming growth factor-beta by cultured human mesangial cells. Nephrol Dial Transplant 1997;12:438-442.
38. Villamediana LM, Rondeau E, He CJ, Medcalf RL, peraldi MN, Lacave R, Delarue F, Sraer JD: Thrombin regulates components of the fibrinolytic system in human mesangial cells. Kidney Int 1990;38:956-961.
39. Barricos WH, Cortez SL, al-Dahr SS, Schnaper HW: ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/ MMP-2 cascade. Kidney Int 1995;47:1039-1047.
40. Galis ZS, Kranzhofer R, Fenton JW, Libby P: Thrombin promotes activation of matrix metalloproteinase-2 produced by cultured vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1997;17:483-489.
41. Zucker S, Conner C, Di Massimo BI Ende H, Drews M, Seiki M, Bahou WF: Thrombin induces the activation of progelatinase A in vascular endothelial cells. Physiologic regulation of angiogenesis. J Biol Chem 1995;270:23730-23738.
42. Bar-Shavit R, Kahn A, Fenton JW, Wilner G: Chemotactic response of monocytes to thrombin. J Cell Biol 1983;96:282-285.
43. Ali H, Tomhave ED, Richardson RM, Haribabu B, Snyderman R: Thrombin primes responsiveness of selective chemoattractant receptors at a site distal to G protein activation. J Biol Chem 1996;271:3200-3206.
44. Mari B, Imbert V, Belhacene N, Far DF, Peyron JF, Pouyssegur J, Van Obberghen-Schilling E, Rossi B, Auberger P: Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production. J Biol Chem 1994; 269:8517-8523.
45. Kaplanski G, Fabrigoule M, Boulay V, Dinarello CA, Bongrand P, Kaplanski S, Farnarier C: Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-alpha-independent IL-8 secretion and E-selectin expression. J Immunol 1997;158:5435-5441.
46. Sugama Y, Tiruppathi C, Offakidevi K, Andersen TT, Fenton JW, Malik AB: Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: A mechanism for stabilizing neutrophil adhesion. J Cell Biol 1992;119:935-944.
47. Bernatowicz MS, Klimas CE, Hartl KS, Peluso M, Allegretto NJ, Seiler SM: Development of potent thrombin receptor antagonist peptides. J Med Chem 1996;39:4879-4887.