Contrasting effects of alendronate and clodronate on RAW 264 macrophages: The role of a bisphosphonate metabolite

European Journal of Pharmaceutical Sciences

Volumn 8, Issue 2, 1999, Pages 109-118

  Makkonen, Niina ^a   Salminen, Antero ^a,c   Rogers, Michael J ^b   Frith, Julie C ^b   Urtti, Arto ^a   Azhayeva, Elena ^a   Mönkkönen, Jukka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Bisphosphonates; Interleukin 1; Interleukin 6; Macrophages; Metabolism; NF kappa B; Tumor necrosis factor

Indexed keywords

ALENDRONIC ACID; CLODRONIC ACID; DRUG METABOLITE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOSOME; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DNA BINDING; DRUG METABOLISM; ELECTROPHORESIS; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL;

ALENDRONATE; ANALGESICS, NON-NARCOTIC; ANIMALS; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CLODRONIC ACID; CYTOKINES; DIPHOSPHONATES; DRUG CARRIERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LIPOSOMES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; PROTEIN BIOSYNTHESIS; TRANSCRIPTION FACTOR AP-1;

EID: 0032899996     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(98)00065-7     Document Type: Article

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