Charge-modified single chain antibody constructs of monoclonal antibody CC49: Generation, characterization, pharmacokinetics, and biodistribution analysis

Nuclear Medicine and Biology

Volumn 26, Issue 1, 1999, Pages 27-34

  Pavlinkova, Gabriela ^a   Beresford, Guy ^a   Booth, Barbara J M ^a   Batra, Surinder K ^b   Colcher, David ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Antibody engineering; Colon carcinoma xenografts; Isoelectric point; Radioimmunodiagnosis; Single chain fragments

Indexed keywords

MONOCLONAL ANTIBODY CC49;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY AFFINITY; ARTICLE; CANCER TRANSPLANTATION; COLON CARCINOMA; DNA SEQUENCE; DRUG DISTRIBUTION; DRUG UPTAKE; GENETIC ENGINEERING; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOUSE; NONHUMAN; NUDE MOUSE; POLYMERASE CHAIN REACTION; TUMOR LOCALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEOPLASM; ANTIBODY FORMATION; BASE SEQUENCE; CARCINOMA; COLONIC NEOPLASMS; FEMALE; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; IODINE RADIOISOTOPES; ISOELECTRIC POINT; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; NEOPLASM TRANSPLANTATION; POLYMERASE CHAIN REACTION; RADIOPHARMACEUTICALS;

EID: 0032891911     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(98)00075-4     Document Type: Article

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