Modified ligand binding to the naturally occurring Cys-124 variant of the human serotonin 5-HT(1B) receptor

Pharmacogenetics

Volumn 9, Issue 1, 1999, Pages 95-102

  Brüss, Michael ^a   Bönisch, Heinz ^a   Bühlen, Michael ^a   Nöthen, Markus M ^a   Propping, Peter ^a   Göthert, Manfred ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

(Phe 124 Cys) h5 HT(1B) receptor; 5 HT receptor agonists and antagonists; 3H 5 carboxamidotryptamine binding; h5 HT(1B) receptor; Pharmacogenetic differences; Single strand conformation analysis

Indexed keywords

3 [4 (3 CHLOROPHENYL) 1 PIPERAZINYL] 1,1 DIPHENYL 2 PROPANOL; 5 CARBAMOYL N,N DIPROPYLTRYPTAMINE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; COMPLEMENTARY DNA; CYSTEINE; DIHYDROERGOTAMINE; KETANSERIN; METHYSERGIDE; N [4 [5 [3 (2 AMINOETHYL) 1H INDOL 5 YL] 1,2,4 OXADIAZOL 3 YL]BENZYL]METHANESULFONAMIDE; PHENYLALANINE; PROPRANOLOL; SEROTONIN; SEROTONIN 1B RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SUMATRIPTAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; COMPETITION; CONTROLLED STUDY; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; HUMAN; LIGAND BINDING; MAJOR CLINICAL STUDY; MANIC DEPRESSIVE PSYCHOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN VARIANT; SCHIZOPHRENIA;

ANIMALS; BASE SEQUENCE; BIPOLAR DISORDER; COS CELLS; CYSTEINE; DNA PRIMERS; DNA, COMPLEMENTARY; HUMANS; LIGANDS; PROTEIN BINDING; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; SCHIZOPHRENIA;

ANIMALIA;

EID: 0032891794     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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