High IgE in rheumatoid arthritis (RA) patients is complexed with anti- IgE autoantibodies

Clinical and Experimental Immunology

Volumn 115, Issue 1, 1999, Pages 183-188

  Millauer, N ^a   Zuercher, A W ^a   Miescher, S M ^a   Gerber, H A ^a   Seitz, M ^a   Stadler, B M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Allergy; Anti IgE; IgE; Rheumatoid arthritis; Rheumatoid factor

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; ALLERGY; ANTIBODY DETECTION; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; HUMAN; IMMUNOREGULATION; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS;

ADULT; AGED; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY COMPLEX; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; FEMALE; HUMANS; HYPERSENSITIVITY; IMMUNOBLOTTING; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; RHEUMATOID FACTOR;

EID: 0032891147     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00787.x     Document Type: Article

References (41)

1. 1 Goronzy JJ, Weyand CM. T and B cell-dependent pathways in rheumatoid arthritis. Curr Opin Rheumatol 1995; 7:214-21.
2. 2 Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31:315-24.
3. 3 Paimela L, Palasuo T, Leirisalo-Repo M, Helve T, Aho K. Prognostic value of quantitative measurements of rheumatoid factors in early rheumatoid arthritis. Br J Rheumatol 1995; 34:1146-50.
4. 4 Van Zeben D, Hazes JM, Zwinderman AH, Vandenbroucke JP, Breedveld FC. Factors predicting outcome of rheumatoid arthritis: results of a follow-up study. J Rheumatol 1993; 20:1288-96.
5. 5 Houssien DA, Jonsson T, Davies E, Scott DL. Clinical significance of IgA rheumatoid factor subclasses in rheumatoid arthritis. J Rheumatol 1997; 24:2119-22.
6. 6 Mannik M, Nardella FA. IgG rheumatoid factors and self-association of these antibodies. Clin Rheum Dis 1985; 11:551-72.
7. 7 Marone G, Casolaro V, Paganelli R, Quinti I. IgG anti-IgE from atopic dermatitis induces mediator release from basophils and mast cells. J Invest Dermatol 1989; 93:246-52.
8. 8 Ritter C, Battig M, Kraemer R, Stadler BM. IgE hidden in immune complexes with anti-IgE autoantibodies in children with asthma. J Allergy Clin Immunol 1991; 88:793-801.
9. 9 Haba S, Nisonoff A. Role of antibody and T cells in the long-term inhibition of IgE synthesis. Proc Natl Acad Sci USA 1994; 91:604-8.
10. 10 Stadler BM, Rudolf MP, Zuercher AW, Miescher S, Vogel M. Anti-IgE in allergic sensitization. Immunol Cell Biol 1996; 74:195-200.
11. 11 Stämpfli MR, Miescher S, Aebischer I, Zuercher AW, Stadler BM. Inhibition of human IgE synthesis by anti-IgE antibodies requires divalent recognition. Eur J Immunol 1994; 24:2161-7.
12. 12 Corne J, Djukanovic R, Thomas L et al. The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety and pharmacokinetics. J Clin Invest 1997; 99:879-87.
13. 13 Rudolf MP, Vogel M, Kricek F et al. Epitope-specific antibody response to IgE by mimotope immunization. J Immunol 1998; 160:3315-21.
14. 14 Grennan DM, Palmer DG. Serum IgE concentration in rheumatoid arthritis: lack of correlation with gold toxicity. Br Med J 1979; 2:1477-8.
15. 15 Hunder GG, Gleich GJ. Immunoglobulin E (IgE) levels in serum and synovial fluid in rheumatoid arthritis. Arthritis Rheum 1974; 17:955-63.
16. 16 O'Driscoll BR, Milburn HJ, Kemeny DM, Cochrane GM, Panayi GS. Atopy and rheumatoid arthritis. Clin Allergy 1985; 15:547-53.
17. 17 Hasan WU, Keaney NP, Holland CD, Kelly CA. Bronchial reactivity and airflow obstruction in rheumatoid arthritis. Ann Rheum Dis 1994; 53:511-4.
18. 18 Allanore Y, Hilliquin P, Coste Renoux M, Menkès CJ. Decreased prevalence of atopy in rheumatoid arthritis. Lancet 1998; 351:497.
19. 19 Bartholomew JS, Evanson JM, Wooley DE. Serum IgE anti-cartilage collagen antibodies in rheumatoid patients. Rheumatol Int 1991; 11:37-40.
20. 20 Mizushima Y, Shoji Y, Hoshi K, Kiyokawa S. Detection and significance of IgE rheumatoid factors. J Rheumatol 1984; 11:22-26.
21. 21 Knutti-Muller JM, Stadler BM, Magnusson CM, de Weck AL. Human IgE synthesis in vitro. Detection with monoclonal antibodies. Allergy 1986; 41:457-67.
22. 22 Neuberger MS, Williams GT, Mitchell EB, Jouhal SS, Flanagan JG, Rabbitts TH. A hapten-specific chimaeric IgE antibody with human physiological effector function. Nature 1985; 314:268-70.
23. 23 Zuercher AW, Lang AB, Aebischer I, Miescher S, Stadler BM. IgE-producing hybridomas established after B-cell culture in the CD40 system. Immunol Letters 1995; 46:49-57.
24. 24 Arnett FC. Seronegative spondylarthropathies. Bull Rheum Dis 1987; 37:1-12.
25. 25 Derer MM, Miescher S, Johansson B, Frost H, Gordon J. Application of the dot immunobinding assay to allergy diagnosis. J Allergy Clin Immunol 1984; 74:85-92.
26. 26 Vassella CC, de Weck AL, Stadler BM. Influence of IgE fragments on IgE determination. Int Arch Allergy Appl Immunol 1990; 92:272-80.
27. 27 Klink M, Cline MG, Halonen M, Burrows B. Problems in defining normal limits for serum IgE. J Allergy Clin Immunol 1990; 85:440-4.
28. 28 De Clerck LS, Gigase PL, Bridts CH, Stevens WJ. Role of IgM-rheumatoid factor interference in the determination of total serum IgE and IgE-containing circulating immune complexes. Clin Exp Immunol 1988; 72:32-36.
29. 29 Al-Balaghi S, Strom H, Moller E. High incidence of spontaneous Ig-producing lymphocytes in peripheral blood and synovial fluid of patients with active seropositive rheumatoid arthritis. Scand J Immunol 1982; 16:69-76.
30. 30 Sutton BJ, Could HJ. The human IgE network. Nature 1993; 366:421-8.
31. 31 Rissoan MC, van Kooten C, Chomarat P, Galibert L, Durand I, Thivolet-Bejui F, Miossec P, Banchereau J. The functional CD40 antigen of fibroblasts may contribute to the proliferation of rheumatoid synovium. Clin Exp Immunol 1996; 106:481-90.
32. 32 MacDonald KP, Nishioka Y, Lipsky PE, Thomas R. Functional CD40 ligand is expressed by T cells in rheumatoid arthritis. J Clin Invest 1997; 100:2404-14.
33. 33 Durie FH, Fava RA, Foy FM, Aruffo A, Ledbetter JA, Noelle RJ. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science 1993; 261:1328-30.
34. 34 Feldmann M, Brennan FM, Maini RN. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 1996; 14:397-440.
35. 35 Gauchat IF, Aversa G, Gascan H, de Vries JE. Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production. Int Immunol 1992; 4:397-406.
36. 36 Gruber B, Pozuansky M, Boss E, Partin J, Gorevic P, Kaplan AP. Characterization and functional studies of rheumatoid synovial mast cells. Arthritis Rheum 1986; 29:944-55.
37. 37 De Clerck LS, Struyf NJ, Bridts CH et al. Humoral immunity and composition of immune complexes in patients with rheumatoid arthritis, with special reference to IgE-containing immune complexes. Clin Exp Rheumatol 1989; 7:485-92.
38. 38 Posnett DN, Edinger J. When do microbes stimulate rheumatoid factor? J Exp Med 1997; 185:1721-3.
39. 39 McCullock J, Lydyard PM, Rook GAW. Rheumatoid arthritis: how well do the theories fit the evidence? Clin Exp Immunol 1993; 92:1-6.
40. 40 Olee T, Lu EW, Huary F, Soto-Gil RW, Deftos M, Kozin F, Carson DA, Chen PP. Genetic analysis of self-associating immunoglobulin G rheumatoid factor from two rheumatoid synovia implicates an antigen-driven response. J Exp Med 1992; 175:831-42.
41. 41 Silman AJ. Is rheumatoid arthritis an infectious disease? Brit Med J 1991; 303:524/786.