Concomitant gastrin and ERBB2 gene amplifications at 17q12-q21 in the intestinal type of gastric cancer

Genes Chromosomes and Cancer

Volumn 24, Issue 1, 1999, Pages 24-29

  Vidgren, Virve ^a   Varis, Asta ^a   Kokkola, Arto ^b   Monni, Outi ^a   Puolakkainen, Pauli ^b   Nordling, Stig ^a   Forozan, Farahnaz ^c   Kallioniemi, Anne ^c   Vakkari, Marja Leena ^a   Kivilaakso, Eero ^b   Knuutila, Sakari ^a,b,d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d The Department of Medical Genetics   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN;

ARTICLE; BREAST CANCER; CARCINOGENESIS; CELLULAR DISTRIBUTION; CHROMOSOME 17Q; CLINICAL ARTICLE; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; STOMACH CANCER;

BREAST NEOPLASMS; CARCINOMA; CHROMOSOMES, HUMAN, PAIR 17; GASTRINS; GASTROINTESTINAL NEOPLASMS; GENE AMPLIFICATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; RECEPTOR, ERBB-2; TUMOR CELLS, CULTURED;

EID: 0032889641     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199901)24:1<24::AID-GCC4>3.0.CO;2-H     Document Type: Article

References (18)

1. Anderson LA, Friedman L, Osborne-Lawrence S, Lynch E, Weissenbach J, Bowcock A, King MC. 1993. High-density genetic map of the BRCA1 region of chromosome 17q12-q21. Genomics 17:618-623.
2. Berner J-M, Forus A, Elkahloun A, Meltzer P, Fodstad Ø, Myklebost O. 1996. Separate amplified regions encompassing CDK2 and MDM2 in human sarcomas. Genes Chromosomes Cancer 17:254-259.
3. Cremer T, Landegent J, Brückner A, Scholl HP, Schardin M, Hager, HD, Devilee P, Pearson P, van der Ploeg M. 1986. Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: Diagnosis of trisomy 18 with probe L.184. Hum Genet 74:346-352.
4. Falck VG, Gullick WJ. 1989. c-erbB-2 oncogene product staining in gastric adenocarcinoma. An immunohistochemical study. J Pathol 159:107-111.
5. Hyytinen E, Visakorpi T, Kallioniemi A, Kallioniemi O-P, Isola JJ. 1994. Improved technique for analysis of formalin-fixed, paraffin-embedded tumors by fluorescence in situ hybridization. Cyrometry 16:93-99.
6. Jain S, Isabel Filipe M, Gullick WJ, Lindehan J, Morris RW. 1991. c-erbB-2 proto-oneogene expression and its relationship to survival in gastric carcinoma: An immunohistochemical study on archival material. Int J Cancer 48:668-671.
7. Knuutila S, Björkqvist A-M, Autio K, Tarkkanen M, Wolf M, Monni O, Szymanska J, Larramendy ML, Tapper J, Pere H, El-Rifai W, Hemmer S, Wasenius V-M, Vidgren V, Zhu Y. 1998. DNA copy number amplifications in human neoplasms. Review of comparative genomic hybridization studies. Am J Pathol 152:1107-1123.
8. Kokkola A, Monni O, Puolakkainen P, Larramendy ML, Victorzon M, Nordling S, Haapiainen R, Kivilaakso E, Knuutila S. 1997. 17q12-21 Amplicon, a novel recurrent genetic change in intestinal type of gastric carcinoma: A comparative genomic hybridization study. Genes Chromosomes Cancer 20:38-43.
9. Laurén P. 1965. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. Acta Pathol Microbiol Scand 64:31-49.
10. Lemoine NR, Jain S, Silvestre F, Lopes C, Hughes CM, McLelland E, Gullick WJ, Isabel Filipe M. 1991. Amplification and overexpression of the EGF receptor and c-erbB-2 proto-oncogenes in human stomach cancer. Br J Cancer 64:79-83.
11. Monni O, Joensuu H, Franssila K, Klefstrom J, Alitalo K, Knuutila S. 1997. BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma. Blood 90:1168-1174.
12. Mor O, Ranzani GN, Ravia Y, Rotman G, Gutman M, Manor A, Amadori D, Houldsworth J, Hollstein M, Schwab M, Shiloh Y. 1993. DNA amplification in human gastric carcinomas. Cancer Genet Cytogenet 65:111-114.
13. Rakic S, Milicevic MN. 1991. Serum gastrin levels in patients with intestinal and diffuse type of gastric cancer. Br J Cancer 64:1189.
14. Ranzani GN, Renault B, Pellegata NS, Fattorini P, Magni E, Bacci F, Amadori D. 1993. Loss of heterozygosity and K-ras gene mutations in gastric cancer. Hum Genet 92:244-249.
15. Tahara E. 1995. Molecular biology of gastric cancer. World J Surg 19:484-490.
16. Tsugawa K, Fushida S, Yonemura Y. 1993. Amplification of the c-erbB-2 gene in gastric carcinoma: Correlation with survival. Oncology 50:418-425.
17. Watson SA, Durrant LG, Crosbie JD, Morris DL. 1989. The in vitro growth response of primary human colorectal and gastric cancer cells to gastrin. Int J Cancer 43:692-696.
18. Wolf M, Aaltonen LA, Szymanska J, Tarkkanen M, Blomqvist C, Berner J-M, Myklebost O, Knuutila S. 1997. Complexity of 12q13-22 amplicon in liposarcoma: Microsatellite repeat analysis. Genes Chromosomes Cancer 18:66-70.