Intraregional variation in expression of serotonin transporter messenger rna by 5-hydroxytryptamine neurons

Neuroscience

Volumn 88, Issue 1, 1999, Pages 169-183

  Rattray, M ^a   Michael, G J ^b   Lee, J ^a   Wotherspoon, G ^b   Bendotti, C ^c   Priestley, J V ^b  

^a UMDS   (United Kingdom)

^b Biomed Sci Qu Mary Westfield C ^*  (United Kingdom)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

5 hydroxytryptamine uptake; In situ hybridization; Neurotoxins; Raphe; SERT

Indexed keywords

CYTOTOXIN; MESSENGER RNA; SEROTONIN; SEROTONIN TRANSPORTER;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL SPECIFICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN UPTAKE; SEROTONINERGIC NERVE;

ANIMALS; BRAIN; CARRIER PROTEINS; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NEURONS; ORGAN SPECIFICITY; RAPHE NUCLEI; RATS; RNA, MESSENGER; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TRANSCRIPTION, GENETIC;

EID: 0032889598     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00231-0     Document Type: Article

References (63)

1. Åberg-Wigstedt A. The antidepressant effects of 5-HT uptake inhibitors. Br. J. Psychiat. 155(8):1989;32-40.
2. Amara S. G., Kuhar M. J. Neurotransmitter transporters - recent progress. A. Rev. Neurosci. 16:1993;73-93.
3. Anderson E. J., McFarland D., Kimelberg H. K. Serotonin uptake by astrocytes in situ. Glia. 6:1992;9-18.
4. Appel N. M., Contrera J. F., De Souza E. B. Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies. J. Pharmac. exp. Ther. 249:1989;928-943.
5. Appel N. M., Mitchell W. M., Contrera J. F., De Souza E. B. Effects of high-dose fenfluramine on monoamine uptake sites in rat brain: assessment using quantitative autoradiography. Synapse. 6:1990;33-44.
6. Austin M. C., Bradley C. C., Mann J. J., Blakely R. D. Expression of serotonin transporter mRNAs in the human brain. J. Neurochem. 62:1994;2362-2367.
7. Battaglia G., Brooks B. P., Kulsakdinun C., De Souza E. B. Pharmacological profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites. Eur. J. Pharmac. 149:1988;159-163.
8. Battaglia G., Sharkey J., Kuhar M. J., De Souza E. B. Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography. Synapse. 8:1991;249-260.
9. Bel N., Figueras G., Vilaró T., Suñol C., Artigas F. Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain. Eur. J. Neurosci. 9:1997;1728-1738.
10. Bendotti C., Baldessari S., Ehret M., Tarizzo G., Samanin R. Effect of d-fenfluramine and 5,7-dihydroxytryptamine on the levels of trypophan hydroxylase and its mRNA in rat brain. Molec. Brain Res. 19:1993;257-261.
11. Bendotti C., Servadio A., Forloni G., Angeretti N., Samanin R. Increased tryptophan hydroxylase mRNA in raphe serotoninergic neurons spared by 5,7-dihydroxytryptamine. Molec. Brain Res. 8:1990;343-348.
12. 3H] paroxetine as an in vivo ligand for serotonin uptake sites - a quantitative autoradiographic study in the rat brain. Synapse. 13:1993;1-9.
13. Blakely R. D., Berson H. E., Freemeau R. T. Jr., Caron M. G., Peck M. M., Prince H. K., Bradley C. C. Cloning and expression of a functional serotonin transporter from rat brain. Nature. 354:1991;66-70.
14. Blanchard V., Raisman-Vozari R., Vyas S., Michel P. P., Javoy-Agid F., Uhl G., Agid Y. Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon. Molec. Brain Res. 22:1994;29-40.
15. Cerruti C., Walther D. M., Kuhar M. J., Uhl G. R. Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain. Molec. Brain Res. 18:1993;181-186.
16. Dahlström A., Fuxe K. Evidence for the existence of monamine-containing neurons in the central nervous system. I. Demonstration of monoamines in cell bodies of brain neurons. Acta physiol. scand. 232(Suppl.):1964;1-55.
17. Darmon M. C., Guibert B., Leviel V., Ehret M., Maître M., Mallet J. Sequence of two mRNAs encoding active tryptophan hydroxylase. J. Neurochem. 51:1988;312-316.
18. + dependent, fluoxetine sensitive serotonin uptake by astrocytes tissue-printed from rat cerebral cortex. J. Neurosci. 14:1994;4972-4986.
19. 3H-paroxetine-labeled serotonin uptake sites in rat brain. Synapse. 1:1987;488-496.
20. Descarries L., Watkins K. C., Garcia S., Beaudet A. The serotonin neurons in nucleus raphe dorsalis of the adult rat. A light and electron microscope radioautographic study. J. comp. Neurol. 207:1982;239-254.
21. 3H-paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment. J. Neurochem. 58:1992;250-257.
22. Dow R. C., Laszlo I., Ritchie I. M. Cellular localization of the uptake of 5-hydroxytryptamine in the area postrema of the rabbit after injection into a lateral ventricle. Br. J. Pharmac. 49:1973;580-587.
23. Fujita M., Shimada S., Maeno H., Nishimura T., Tohyama M. Cellular localisation of serotonin transporter messenger RNA in the rat brain. Neurosci. Lett. 162:1993;59-62.
24. 3H]-serotonin. Naunyn-Schmeideberg's. Arch. Pharmac. 345:1992;1-6.
25. 1A receptors and 5-HT uptake sites in the rat brain. J. chem. Neuroanat. 7:1994;65-73.
26. Görcs T. J., Liposits Z., Palay S. L., Chan-Palay V. Serotonin neurons on the ventral brain surface. Proc. natn. Acad. Sci. U.S.A. 82:1985;7449-7452.
27. Hajos M., Gartside S. E., Sharp T. Inhibition of median and dorsal raphe neurons following administration of the selective serotonin reuptake inhibitor paroxetine. Naunyn-Schmeideberg's Arch. Pharmac. 351:1995;624-629.
28. Hajos M., Gartside S. E., Villa A. E. P., Sharp T. Evidence for a repetitive (burst) firing pattern in a subpopulation of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat. Neuroscience. 69:1995;189-197.
29. Hensler J. G., Ferry R. C., Labow D. M., Kovachich G. B., Frazer A. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse. 17:1994;1-15.
30. Hoffman B. J., Mezey E., Brownstein M. J. Cloning of a serotonin transporter affected by antidepressants. Science. 254:1991;579-580.
31. 3H-imipramine localisation and relationship to serotonin transport. J. Pharmac. exp. Ther. 252:1990;410-418.
32. Invernizzi R., Carli M., Di Clemente A., Samanin R. Administration of 8-hydroxy-2-(di-n-propylamino)tetralin in raphe nuclei dorsalis and medianus reduces serotonin synthesis in the rat brain: differences in potency and regional selectivity. J. Neurochem. 56:1991;243-247.
33. Johnson M., Hanson G. R., Gibb J. W. Effects of N-ethyl-3,4-methylenedioxymethamphetamine (MDE) on central serotonergic and dopaminergic systems of the rat. Biochem. Neuropharmac. 36:1987;4085-4093.
34. Kleven M. S., Seiden L. S. D-, L- and DL-fenfluramine cause long-lasting depletions of serotonin in rat brain. Brain Res. 505:1989;351-353.
35. Kosofsky B. E., Molliver M. E. The serotoninergic innervation of cerebral cortex: different classes of axon terminals arise from dorsal and median raphe nuclei. Synapse. 1:1987;153-168.
36. Lebrand C., Cases O., Adelbrecht C., Doye A., Alvarez C., El Mestikawy S., Seif I., Gaspar P. Transient uptake and storage of serotonin in developing thalamic neurons. Neuron. 17:1996;823-835.
37. Lorang D., Amara S. G., Simerly R. B. Cell-type-specific expression of catecholamine transporters in the rat brain. J. Neurosci. 14:1994;4903-4914.
38. Mager S., Min C., Henry D. J., Chavkin C., Hoffman B. J., Davidson N., Lester H. A. Conducting state of a mammalian serotonin transporter. Neuron. 12:1994;845-859.
39. Mamounas L. A., Molliver M. E. Evidence for dual serotonergic projections to neocortex: axons from the dorsal and median raphe nuclei are differentially vulnerable to the neurotoxin p-chloroamphetamine (PCA). Expl Neurol. 102:1988;23-36.
40. Mamounas L. A., Mullen C. A., O'Hearn E., Molliver M. E. Dual serotonergic projections to forebrain in the rat: morphologically distinct 5-HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives. J. comp. Neurol. 314:1991;558-586.
41. McQuade R., Sharp T. Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in the forebrain of rat using microdialysis. J. Neurochem. 69:1997;791-796.
42. Molliver M. E. Serotonergic neuronal systems: what their anatomic organization tells us about their function. J. clin. Psychopharmac. 7(Suppl. 6):1987;3S-23S.
43. Nelson P. J., Rudnick G. Coupling between platelet 5-hydroxytryptamine and potassium transporter. J. biol. Chem. 254:1979;10084-10089.
44. Park D. H., Stone D. M., Baker H., Kim K. S., Joh T. H. Early induction of rat brain tryptophan hydroxylase (TpH) mRNA following parachlorophenylalanine (PCPA) treatment. Molec. Brain Res. 22:1994;20-28.
45. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates. 2nd edn. Academic, London.
46. Piercey M. F., Lum J. T., Palmer J. R. Effects of MDMA ("ecstasy") on firing rates of serotonergic dopaminergic and noradrenergic neurons in the rat. Brain Res. 526:1990;203-206.
47. Priestley J. V., Wotherspoon G., Savery D., Averill S., Rattray M. A combined in situ hybridisation and immunofluorescence procedure allowing visualisation of peptide mRNA and serotonin in single sections. J. Neurosci. Meth. 48:1993;99-110.
48. Qian Y., Melikian H. E., Rye D. B., Levey A. I., Blakely R. D. Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies. J. Neurosci. 15:1995;1261-1274.
49. Raison S., Rousset C., Pujol J., Weissmann D. p-Chlorophenylalanine-induced alteration of somatodendritic levels of tryptophan hydroxylase within the rat mesencephalic raphe nuclei. J. Neurochem. 67:1996;2124-2133.
50. Rattray M., Baldessari S., Gobbi M., Mennini T., Samanin R., Bendotti C. p-Chlorophenylalanine changes in serotonin transporter mRNA levels and expression of the gene product. J. Neurochem. 67:1996;463-472.
51. Rattray M., Wotherspoon G., Savery D., Baldessari S., Marden C., Priestley J. V., Bendotti C. Chronic d-fenfluramine decreases serotonin transporter mRNA expression in dorsal raphe nucleus. Eur. J. Pharmac. 268:1994;439-442.
52. Rattray M., Wotherspoon G., Savery D., Marden C., Lopez Costa J. J., Bendotti C., Priestley J. V. Fenfluramine and MDMA down-regulate serotonin transporter messenger RNA in subdivisions of the rat dorsal raphe complex. Soc. Neurosci. Abstr. 19:1993;495.
53. Rudnick G., Wall S. C. The molecular mechanism of "ecstasy" 3,4-methylenedioxymethamphetamine (MDMA): serotonin transporters are targets for MDMA-induced serotonin release. Proc. natn. Acad. Sci. U.S.A. 89:1992;1817-1821.
54. 3H-indalpine binding sites in the rat brain. II. Regional distribution. J. Neurochem. 45:1985;521-526.
55. Smith G. S. T., Savery D., Marden C. M., Lopez Costa J. J., Averill S., Priestley J. V., Rattray M. Peptide gene expression in the midbrain periaqueductal grey matter of the rat. The distribution of messenger RNAs encoding enkephalin, substance P, somatostatin, galanin, vasoactive intestinal polypeptide, neuropeptide Y and calcitonin gene related peptide. J. comp. Neurol. 350:1994;23-40.
56. Steinbusch H. W. M. Distribution of serotonin immunoreactivity in the central nervous system of the rat - cell bodies and terminals. Neuroscience. 6:1981;557-618.
57. Swan M. C., Najlerahim A. R., Bennett J. P. Expression of serotonin transporter mRNA in rat brain: presence in neuronal and non-neuronal cells and effect of paroxetine. J. chem. Neuroanat. 13:1997;71-76.
58. Tao R., Auerbach S. B. Involvement of the dorsal raphe but not median raphe nucleus in morphine-induced increases in serotonin release in the rat forebrain. Neuroscience. 68:1995;553-561.
59. Tison F., Normand E., Jaber M., Aubert I., Bloch B. Aromatic l-amino-acid decarboxylase (DOPA decarboxylase) gene expression in dopaminergic and serotoninergic cells of the rat brainstem. Neurosci. Lett. 127:1991;203-206.
60. Tohyama I., Kameyama M., Kimura H. Quantitative morphometric analysis of two types of serotonin-immunoreactive nerve fibres differentially responding to p-chlorophenylalanine treatment in the rat brain. Neuroscience. 26:1988;971-991.
61. Wiklund L., Léger L., Persson M. Monoamine cell distribution in the cat brain stem. A fluorescence histochemical study with quantification of indolaminergic and locus coeruleus cell groups. J. comp. Neurol. 203:1980;613-647.
62. Wilson M. A., Ricaurte G. A., Molliver M. E. Distinct morphologic classes of serotonergic axons in primates exhibit differential vulnerability to the psychotropic drug 3,4-methylenedioxymethamphetamine. Neuroscience. 28:1989;121-137.
63. Wotherspoon G., Albert M., Rattray M., Priestley J. V. Serotonin and NADPH diaphorase in the dorsal raphe nucleus of the adult rat. Neurosci. Lett. 173:1994;31-36.