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Volumn 38, Issue SUPPL. 2, 1999, Pages 20-27

Pharmacokinetics of orally administered antifungals in onychomycosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; FLUCONAZOLE; GRISEOFULVIN; ITRACONAZOLE; KETOCONAZOLE; TERBINAFINE;

EID: 0032888518     PISSN: 00119059     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-4362.1999.00010.x     Document Type: Article
Times cited : (18)

References (56)
  • 1
    • 0021110895 scopus 로고
    • The antifungal activity of ketoconazole
    • Van Cutsem J. The antifungal activity of ketoconazole. Am J Med 1983; 74: 9-15.
    • (1983) Am J Med , vol.74 , pp. 9-15
    • Van Cutsem, J.1
  • 2
    • 0344957018 scopus 로고    scopus 로고
    • Pharmacokinetics in onychomycosis
    • Jacobs PH, Nall L, eds. New York: Marcel Dekker, Inc.
    • De Doncker P. Pharmacokinetics in Onychomycosis. In: Jacobs PH, Nall L, eds. Fungal Disease: Biology Immunology and Diagnosis. New York: Marcel Dekker, Inc., 1997: 517-545.
    • (1997) Fungal Disease: Biology Immunology and Diagnosis , pp. 517-545
    • De Doncker, P.1
  • 3
    • 0344957017 scopus 로고
    • Clinical evaluation of the effect of formulation variables on therapeutic performance of drugs
    • Riegelman S. Clinical evaluation of the effect of formulation variables on therapeutic performance of drugs. Drug Inform Bull 1969; 3: 59.
    • (1969) Drug Inform Bull , vol.3 , pp. 59
    • Riegelman, S.1
  • 4
    • 0015124660 scopus 로고
    • Absorption characteristics of solid dispersed and micronized griseofulvin in man
    • Chiou WL, Riegelman S. Absorption characteristics of solid dispersed and micronized griseofulvin in man. J Pharm Sci 1971; 60: 1376-1380.
    • (1971) J Pharm Sci , vol.60 , pp. 1376-1380
    • Chiou, W.L.1    Riegelman, S.2
  • 5
    • 0021996054 scopus 로고
    • Human plasma and skin blister fluid levels of griseofulvin following a single oral dose
    • Schäfer-Korting M, Korting HC, Mutschler E. Human plasma and skin blister fluid levels of griseofulvin following a single oral dose. Eur J Clin Pharmacol 1985; 29: 109-113.
    • (1985) Eur J Clin Pharmacol , vol.29 , pp. 109-113
    • Schäfer-Korting, M.1    Korting, H.C.2    Mutschler, E.3
  • 6
    • 0027519479 scopus 로고
    • Treatment of tinea unguium with medium and high doses of ultramicrosize griseofulvin compared with itraconazole
    • Korting HC, Schäfer-Korting M, Zienicke H, et al. Treatment of tinea unguium with medium and high doses of ultramicrosize griseofulvin compared with itraconazole. Antimicrob Ag Chemoth 1993; 37: 2064-2068.
    • (1993) Antimicrob Ag Chemoth , vol.37 , pp. 2064-2068
    • Korting, H.C.1    Schäfer-Korting, M.2    Zienicke, H.3
  • 7
    • 0022503212 scopus 로고
    • Pharmacokinetics and dose proportionally of ketoconazole in normal volunteers
    • Huang Y-C, Colaizzi JL, Bierman RH, et al. Pharmacokinetics and dose proportionally of ketoconazole in normal volunteers. Antimicrob Ag Chemoth 1986; 30: 206-210.
    • (1986) Antimicrob Ag Chemoth , vol.30 , pp. 206-210
    • Huang, Y.-C.1    Colaizzi, J.L.2    Bierman, R.H.3
  • 8
    • 0023918346 scopus 로고
    • Effect of food and gastric acidity on absorption of orally administered ketoconazole
    • Lewawongs P, barone JA, Colaizzi JL, et al. Effect of food and gastric acidity on absorption of orally administered ketoconazole. Clin Pharm 1988; 7: 228-235.
    • (1988) Clin Pharm , vol.7 , pp. 228-235
    • Lewawongs, P.1    Barone, J.A.2    Colaizzi, J.L.3
  • 9
    • 0025053423 scopus 로고
    • Pharmacokinetics of terbinafine in humans
    • Jenssen JC. Pharmacokinetics of terbinafine in humans. J Dermatol Treatment 1990; 1 (Suppl. 2): 15-18.
    • (1990) J Dermatol Treatment , vol.1 , Issue.2 SUPPL. , pp. 15-18
    • Jenssen, J.C.1
  • 10
    • 0026544319 scopus 로고
    • Terbinafine: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial mycoses
    • Balfour JA, Faulds D. Terbinafine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial mycoses. Drugs 1992; 43: 259-284.
    • (1992) Drugs , vol.43 , pp. 259-284
    • Balfour, J.A.1    Faulds, D.2
  • 12
    • 0022353680 scopus 로고
    • Pharmacokinetic evaluation of UK-49,858, a metabolically stable triazole antifungal drug, in animals and man
    • Humphrey MJ, Jevons S, Tarbit MH. Pharmacokinetic evaluation of UK-49,858, a metabolically stable triazole antifungal drug, in animals and man. Antimicrob Ag Chemother 1985; 28: 648-653.
    • (1985) Antimicrob Ag Chemother , vol.28 , pp. 648-653
    • Humphrey, M.J.1    Jevons, S.2    Tarbit, M.H.3
  • 13
    • 0001858907 scopus 로고
    • A review of the pharmacokinetics of fluconazole (UK-49,858) in laboratory animals and man
    • Fromtling RA, ed. Barcelona: JR Prous Science Publishers SA
    • Brammer KW, Tarbit MH. A review of the pharmacokinetics of fluconazole (UK-49,858) in laboratory animals and man. In: Fromtling RA, ed. Recent Trends in the Discovery, Development and Evaluation of Antifungal Agents. Barcelona: JR Prous Science Publishers SA, 1987: 141-150.
    • (1987) Recent Trends in the Discovery, Development and Evaluation of Antifungal Agents , pp. 141-150
    • Brammer, K.W.1    Tarbit, M.H.2
  • 14
    • 0024517330 scopus 로고
    • Itraconazole: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in superficial and systemic mycoses
    • Grant SM, Clissold SP. Itraconazole: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in superficial and systemic mycoses. Drugs 1989; 37: 310-344.
    • (1989) Drugs , vol.37 , pp. 310-344
    • Grant, S.M.1    Clissold, S.P.2
  • 15
    • 17544386618 scopus 로고    scopus 로고
    • Pharmacokinetics of three doses (150, 300, and 450 mg) in distal subungual onychomycosis of the toenail
    • Rich P, Scher RK, Breneman D, et al. Pharmacokinetics of three doses (150, 300, and 450 mg) in distal subungual onychomycosis of the toenail. J Am Acad Dermatol 1998; 38: S103-S109.
    • (1998) J Am Acad Dermatol , vol.38
    • Rich, P.1    Scher, R.K.2    Breneman, D.3
  • 16
    • 0024847184 scopus 로고
    • The clinical pharmacokinetics of itraconazole: An overview
    • Heykants J, Van Peer A, Van de Velde V, et al. The clinical pharmacokinetics of itraconazole: an overview. Mycoses 1989; 32 (Suppl.): 67-87.
    • (1989) Mycoses , vol.32 , Issue.SUPPL. , pp. 67-87
    • Heykants, J.1    Van Peer, A.2    Van De Velde, V.3
  • 17
    • 0023173133 scopus 로고
    • Activity of orally, topically and parenterally administered itraconazole in the treatment of superficial and deep mycoses: Animal models
    • Van Cutsem J, Van Gerven F, Janssen PAJ. Activity of orally, topically and parenterally administered itraconazole in the treatment of superficial and deep mycoses: animal models. Rev Infect Dis 1987; 9 (Suppl. 1): 15-32.
    • (1987) Rev Infect Dis , vol.9 , Issue.1 SUPPL. , pp. 15-32
    • Van Cutsem, J.1    Van Gerven, F.2    Janssen, P.A.J.3
  • 18
    • 0016838053 scopus 로고
    • Use of 24-hr urinary excretion to assess the bioavailability of griseofulvinin humans
    • Bates TR, Sequeira JAL. Use of 24-hr urinary excretion to assess the bioavailability of griseofulvinin humans. J Pharm Sci 1975; 64: 709.
    • (1975) J Pharm Sci , vol.64 , pp. 709
    • Bates, T.R.1    Sequeira, J.A.L.2
  • 19
    • 0014792909 scopus 로고
    • Parameters affecting absorption of griseofulvin in a human subject using urinary metabolite excretion data
    • Kabasakalian P. Parameters affecting absorption of griseofulvin in a human subject using urinary metabolite excretion data. J Pharm Sci 1970; 59: 595.
    • (1970) J Pharm Sci , vol.59 , pp. 595
    • Kabasakalian, P.1
  • 21
    • 0001362120 scopus 로고
    • The kinetics of ketoconazole in animals and man
    • Gascoigne EW, Barton GJ, Michaels M, et al. The kinetics of ketoconazole in animals and man. Clin Res Rev 1981; 1: 177-187.
    • (1981) Clin Res Rev , vol.1 , pp. 177-187
    • Gascoigne, E.W.1    Barton, G.J.2    Michaels, M.3
  • 23
    • 0026556493 scopus 로고
    • Dose-proportional pharmacokinetics of terbinafine and its N-demethylated metabolite in healthy volunteers
    • Kovarik JM, Kirkesselis Humbert H, Grass P, Kutz K. Dose-proportional pharmacokinetics of terbinafine and its N-demethylated metabolite in healthy volunteers. Br J Dermatol 1992; 126 (Suppl. 39): 8-13.
    • (1992) Br J Dermatol , vol.126 , Issue.39 SUPPL. , pp. 8-13
    • Kovarik, J.M.1    Kirkesselis Humbert, H.2    Grass, P.3    Kutz, K.4
  • 24
    • 0013566350 scopus 로고
    • Terbinafine (Lamisil®). The first oral fungistatic and fungicidal allylamine
    • Samsoen M. Terbinafine (Lamisil®). The first oral fungistatic and fungicidal allylamine. Nouv Dermatol 1992; 11: 743-762.
    • (1992) Nouv Dermatol , vol.11 , pp. 743-762
    • Samsoen, M.1
  • 25
    • 0029585251 scopus 로고
    • Nail incorporation kinetics of terbinafine in onychomycosis patients
    • Schatz F, Brautigam M, Dobrowolski E, et al. Nail incorporation kinetics of terbinafine in onychomycosis patients. Clin Exp Dermatol 1995; 20: 377-383.
    • (1995) Clin Exp Dermatol , vol.20 , pp. 377-383
    • Schatz, F.1    Brautigam, M.2    Dobrowolski, E.3
  • 27
    • 0025603012 scopus 로고
    • Clinical pharmacology of fluconazole
    • Dudley MN. Clinical pharmacology of fluconazole. Pharmacotherapy 1990; 10 (Suppl.): 141S-145S.
    • (1990) Pharmacotherapy , vol.10 , Issue.SUPPL.
    • Dudley, M.N.1
  • 28
    • 0019348871 scopus 로고
    • The human nail: Structure, growth and pathological changes
    • Runne U, Orfanos SE. The human nail: structure, growth and pathological changes. Curr Probl Dermatol 1981; 9: 101-149.
    • (1981) Curr Probl Dermatol , vol.9 , pp. 101-149
    • Runne, U.1    Orfanos, S.E.2
  • 29
    • 84989424497 scopus 로고
    • Investigations and some physicochemical properties of nails
    • Baran R, Dawber RPR, eds. Blackwell Science, Oxford
    • Baran R, Dawber RPR. Investigations and some physicochemical properties of nails. In: Baran R, Dawber RPR, eds. Diseases of the Nails and Their Management. Blackwell Science, Oxford 1984; 81-104.
    • (1984) Diseases of the Nails and Their Management , pp. 81-104
    • Baran, R.1    Dawber, R.P.R.2
  • 32
    • 0019205357 scopus 로고
    • The ultrastructure and growth of human nails
    • Dawber RPR. The ultrastructure and growth of human nails. Arch Dermatol Res 1980; 269: 197-204.
    • (1980) Arch Dermatol Res , vol.269 , pp. 197-204
    • Dawber, R.P.R.1
  • 34
    • 0021839573 scopus 로고
    • Onychomycosis
    • Zaias N. Onychomycosis. Dermatol Clinics 1985; 3/3: 445-460.
    • (1985) Dermatol Clinics , vol.3 , Issue.3 , pp. 445-460
    • Zaias, N.1
  • 35
    • 0017084526 scopus 로고
    • Plasma concentrations of griseofulvin in healthy volunteers and out-patients treated for onychomcyosis
    • Hägermark O, Berlin A, Wallin I, Boréus LO. Plasma concentrations of griseofulvin in healthy volunteers and out-patients treated for onychomcyosis. Acta Dermatovenereol 1976; 56: 289-296.
    • (1976) Acta Dermatovenereol , vol.56 , pp. 289-296
    • Hägermark, O.1    Berlin, A.2    Wallin, I.3    Boréus, L.O.4
  • 36
    • 0021045462 scopus 로고
    • Orally administered ketoconazole: Route of delivery to the human stratum corneum
    • Harris R, Jones HE, Artis WM. Orally administered ketoconazole: route of delivery to the human stratum corneum. Antimicrob Ag Chemoth 1983; 24: 876-882.
    • (1983) Antimicrob Ag Chemoth , vol.24 , pp. 876-882
    • Harris, R.1    Jones, H.E.2    Artis, W.M.3
  • 37
    • 0026489839 scopus 로고
    • Skin kinetics of azole antifungal drugs
    • Borgers M, Hay R, eds. Rinaldi MG.Publications by Springer-Verlag, New York
    • Cauwenbergh G. Skin kinetics of azole antifungal drugs. In: Borgers M, Hay R, eds. Current Topics in Medical Mycology (Vol 4). Rinaldi MG.Publications by Springer-Verlag, New York, 1992; 88-136.
    • (1992) Current Topics in Medical Mycology , vol.4 , pp. 88-136
    • Cauwenbergh, G.1
  • 38
    • 0027397290 scopus 로고
    • Once-weekly treatment with oral ketoconazole for superficial fungal infections
    • Segal R, Trattner A, Alteras I, et al. Once-weekly treatment with oral ketoconazole for superficial fungal infections. J Am Acad Dermatol 1993; 28: 126-127.
    • (1993) J Am Acad Dermatol , vol.28 , pp. 126-127
    • Segal, R.1    Trattner, A.2    Alteras, I.3
  • 39
    • 0025131405 scopus 로고
    • Nail matrix kinetics of oral terbinafine in onychomysosis and normal nails
    • Finlay AY, Lever LR, Thomas R, Dykes PJ. Nail matrix kinetics of oral terbinafine in onychomysosis and normal nails. J Dermatol Treat 1990; 1 (Suppl. 2): 51-54.
    • (1990) J Dermatol Treat , vol.1 , Issue.2 SUPPL. , pp. 51-54
    • Finlay, A.Y.1    Lever, L.R.2    Thomas, R.3    Dykes, P.J.4
  • 40
    • 0025076882 scopus 로고
    • Determination of terbinafine in nail samples during systemic treatment for onychomycoses
    • Dykes PJ, Thomas R, Finlay AY. Determination of terbinafine in nail samples during systemic treatment for onychomycoses. Br J Dermatol 1990; 123: 481-486.
    • (1990) Br J Dermatol , vol.123 , pp. 481-486
    • Dykes, P.J.1    Thomas, R.2    Finlay, A.Y.3
  • 41
    • 0028283024 scopus 로고
    • Levels of terbinafine in plasma, stratum corneum, dermis-epidermis (without stratum corneum), hair and nails during and after 250 mg terbinafine orally once per day for 7 and 14 days
    • Faergemann J, Zehender H, Millerioux L. Levels of terbinafine in plasma, stratum corneum, dermis-epidermis (without stratum corneum), hair and nails during and after 250 mg terbinafine orally once per day for 7 and 14 days. Clin Exp Dermatol 1994; 19: 121-126.
    • (1994) Clin Exp Dermatol , vol.19 , pp. 121-126
    • Faergemann, J.1    Zehender, H.2    Millerioux, L.3
  • 42
    • 0026528993 scopus 로고
    • Pharmacokinetics of terbinafine in the nail
    • Finlay AY. Pharmacokinetics of terbinafine in the nail. Br J Dermatol 1992; 126 (Suppl. 39): 28-32.
    • (1992) Br J Dermatol , vol.126 , Issue.39 SUPPL. , pp. 28-32
    • Finlay, A.Y.1
  • 43
    • 0344957009 scopus 로고
    • Does the oral dosage of terbinafine influence its concentration in nail?
    • Vienna, 18-21 May Department of Dermatology, University of Vienna, Austria
    • Finlay AY, Thomas R, Chawla M. Does the oral dosage of terbinafine influence its concentration in nail? Dermatology 2000, Vienna, 18-21 May 1993, Department of Dermatology, University of Vienna, Austria, p. 40.
    • (1993) Dermatology 2000 , pp. 40
    • Finlay, A.Y.1    Thomas, R.2    Chawla, M.3
  • 45
    • 0026469938 scopus 로고
    • Pharmacodynamic and pharmacokinetic evaluation of fluconazole in skin and nails
    • Hay RJ. Pharmacodynamic and pharmacokinetic evaluation of fluconazole in skin and nails. Int J Dermatol 1992; 31 (Suppl. 2): 6-7.
    • (1992) Int J Dermatol , vol.31 , Issue.2 SUPPL. , pp. 6-7
    • Hay, R.J.1
  • 46
    • 0028171976 scopus 로고
    • Bioavailability of fluconazole in the skin after oral medication
    • Wildfeuer A, Faergemann J, Laufen H et al. Bioavailability of fluconazole in the skin after oral medication. Mycoses I994; 37: 127-130.
    • (1994) Mycoses , vol.37 , pp. 127-130
    • Wildfeuer, A.1    Faergemann, J.2    Laufen, H.3
  • 47
    • 0344526159 scopus 로고    scopus 로고
    • An open-label, non-comparative study of the efficacy and safety of fluconazole in the treatment of onychomycosis
    • Fraki J, Heikkila H, Kero M, et al. An open-label, non-comparative study of the efficacy and safety of fluconazole in the treatment of onychomycosis. Current Therapeutic Res 1997; 58: 481-491.
    • (1997) Current Therapeutic Res , vol.58 , pp. 481-491
    • Fraki, J.1    Heikkila, H.2    Kero, M.3
  • 48
    • 0029890133 scopus 로고    scopus 로고
    • Levels of fluconazole in normal and diseased nails during and after treatment of onychomycoses in toenails with fluconazole 150 mg once weekly
    • Faergemann J, Iaufen H. Levels of fluconazole in normal and diseased nails during and after treatment of onychomycoses in toenails with fluconazole 150 mg once weekly. Acta Dermatol Venereol 1996; 76: 219-221.
    • (1996) Acta Dermatol Venereol , vol.76 , pp. 219-221
    • Faergemann, J.1    Iaufen, H.2
  • 49
    • 0031749860 scopus 로고    scopus 로고
    • Pharmacokinetics of three once weekly doses (150, 300, and 450 mg) in distal subungual onychomycosis of the fingernail
    • Savin RC, Drake L, Bable D, Stewart DM et al. Pharmacokinetics of three once weekly doses (150, 300, and 450 mg) in distal subungual onychomycosis of the fingernail. J Am Acad Dermatol 1998; 38: S110-116.
    • (1998) J Am Acad Dermatol , vol.38
    • Savin, R.C.1    Drake, L.2    Bable, D.3    Stewart, D.M.4
  • 50
    • 0023883954 scopus 로고
    • Pharmacokinetic profile of orally administered itraconazole in human skin
    • Cauwenbergh G, Degreef H, Heykants J, et al. Pharmacokinetic profile of orally administered itraconazole in human skin. J Am Acad Dermatol 1988; 18: 263-268.
    • (1988) J Am Acad Dermatol , vol.18 , pp. 263-268
    • Cauwenbergh, G.1    Degreef, H.2    Heykants, J.3
  • 51
    • 0025896360 scopus 로고
    • Itraconazole penetrates the nail via the nail matrix and the nail bed: An investigation in onychomycosis
    • Matthieu L, De Doncker P, Cauwenbergh G, et al. Itraconazole penetrates the nail via the nail matrix and the nail bed: an investigation in onychomycosis. Clin Exp Dermatol 1992; 16: 374-376.
    • (1992) Clin Exp Dermatol , vol.16 , pp. 374-376
    • Matthieu, L.1    De Doncker, P.2    Cauwenbergh, G.3
  • 53
    • 9044222883 scopus 로고    scopus 로고
    • Antifungal pulse therapy in onychomycosis: A pharmacokinetic/ pharmacodynamic investigation of monthly cycles of 1-week pulse with itraconazole
    • De Doncker P, Decroix J, Piérard GE, et al. Antifungal pulse therapy in onychomycosis: a pharmacokinetic/ pharmacodynamic investigation of monthly cycles of 1-week pulse with itraconazole. Arch Dermatol 1996; 132: 34-41.
    • (1996) Arch Dermatol , vol.132 , pp. 34-41
    • De Doncker, P.1    Decroix, J.2    Piérard, G.E.3
  • 54
    • 0344094864 scopus 로고    scopus 로고
    • Itraconazole and terbinafine in perspective; from petridish to patient. 7th Congress of the European Academy of Dermatology and Venerology, Nice, France, 7-11 October 1998
    • De Doncker P. Itraconazole and terbinafine in perspective; from petridish to patient. 7th Congress of the European Academy of Dermatology and Venerology, Nice, France, 7-11 October 1998. Eur Acad Dermatol Venerol 1998; 11 (Suppl 2): 595-596.
    • Eur Acad Dermatol Venerol 1998 , vol.11 , Issue.2 SUPPL. , pp. 595-596
    • De Doncker, P.1
  • 56
    • 0028233707 scopus 로고
    • Relevance of broad spectrum and fungicidal activity of antifungals in the treatment of dermatomycosis
    • Clayton Y. Relevance of broad spectrum and fungicidal activity of antifungals in the treatment of dermatomycosis. Br J Dermatol 1994; 130 (Suppl. 43): 7-8.
    • (1994) Br J Dermatol , vol.130 , Issue.43 SUPPL. , pp. 7-8
    • Clayton, Y.1


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