Activation of infiltrating cytotoxic T lymphocytes and lymphoma cell apoptotic rates in gastric malt lymphomas: Differences between high-grade and low-grade cases

American Journal of Pathology

Volumn 155, Issue 3, 1999, Pages 823-829

  Guidoboni, Massimo ^a   Doglioni, Claudio ^b   Laurino, Licia ^b   Boiocchi, Mauro ^a   Dolcetti, Riccardo ^a  

^a CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^b Belluno City Hospital   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GRANZYME B; PERFORIN;

APOPTOSIS; ARTICLE; CANCER GRADING; CYTOTOXIC T LYMPHOCYTE; DIAGNOSTIC VALUE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTIC INFILTRATION; LYMPHOMA CELL; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PRIORITY JOURNAL; STOMACH LYMPHOMA; T LYMPHOCYTE ACTIVATION;

EID: 0032886882     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65181-4     Document Type: Article

References (34)

1. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG: Helicobacter pylori-associated gastritis, and primary B-cell lymphoma. Lancet 1991, 338:1175-1176
2. Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, Orentreich N, Vogelman JH, Friedman GD: Helicobacter pylori infection and gastric lymphoma. N Engl J Med 1994, 330:1267-1271
3. Nakamura S, Aoyagi K, Furuse M, Suekane H, Matsumoto T, Yao T, Sakai Y, Fuchigami T, Yamamoto Y, Tsuneyoshi M, Fujishima M: B-cell monoclonality precedes the development of gastric MALT lymphoma in Helicobacter pylori-associated chronic gastritis. Am J Pathol 1998, 152:1271-1279
4. Hussell T, Isaacson PG, Crabtree JE, Spencer J: The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet 1993, 342:571-574
5. Hussel T, lsaacson PG, Crabtree JE, Spencer J: Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of the mucosa-associated lymphoid tissue. J Pathol 1996, 178:122-127
6. Greiner A, Knorr C, Qin Y, Sebald W, Schimpl A, Banchereau J, Muller-Hermelink HK: Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT-type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation. Am J Pathol 1997, 150:1583-1593
7. Koulis A, Diss T, Isaacson PG, Dogan A: Characterization of tumor-infiltrating T lymphocytes in B-cell lymphomas of mucosa-associated lymphoid tissue. Am J Pathol 1997, 151:1353-1360
8. Graubert TA, Ley TJ: How do lymphocytes kill tumor cells? Clin Cancer Res 1996, 2:785-789
9. Clark WR, Walsh CM, Glass AA, Hayashi F, Matloubian M. Ahmed R: Molecular pathways of CTL-mediated cytotoxicity. Immunol Rev 1995, 146:33-44
10. Kagi D, Ledermann B, Burki K, Zinkernagel RM, Hengartner H: Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu Rev Immunol 1996, 14:207-232
11. Liu CC, Walsh CM, Young JD: Perforin: structure and function, Immunol Today 1995, 16:194-201
12. Smyth MJ, Trapani JA: Granzyes: exogenous proteinases that induce target cell apoptosis. Immunol Today 1995, 16:202-206
13. + T lymphocytes. J Immunol 1990, 144:574-582
14. Tian Q, Streuli M, Saito H, Schlossman SF, Anderson P: A polyadenilate binding protein localized to the granules of cytolytic lymphocytes induce DNA fragmentation in target cells. Cell 1991, 67:629-639
15. Isaacson PG, Norton AJ: Malignant lymphoma of the gastrointestinal tract. Extranodal Lymphomas. Edited by lsaacson PG, Norton AJ Edinburgh, Churchill Livingstone, 1994, pp 15-65
16. de Jong D, Boot H, van Heerde P, Hart GAM, Taal BG: Histological grading in gastric lymphoma: pretreatment criteria and clinical relevance. Gastroenterology 1997, 112:1466-1474
17. Gavrieli Y, Sherman Y, Ben Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J Cell Biol 1992, 119:493-501
18. Migheli A, Cavalla P, Marino S, Schiffer D: A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks. J Neuropathol Exp Neurol 1994, 53:606-616
19. Du M, Singh N, Husseuin A, Isaacson PG, Pan L: Positive correlation between apoptotic and proliferative indices in gastrointestinal lymphomas of mucosa-associated lymphoid tissue (MALT). J Pathol 1996, 178:379-384
20. Gisbertz IAM, Scheuten HC, Bot FJ, Arends JW: Proliferation and apoptosis in primary B-cell non-Hodgkin's lymphoma. Histopathology 1997, 30:152-159
21. Du M, Peng H, Singh N, Isaacson PG, Pan L: The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma. Blood 1995, 86:4587-4593
22. Yasumi K, Quo RJ, Hanai H, Arai H, Kaneko E, Konno H, Takenoshita S.Hagiwara K, Sugimura H: Transforming growth factor β type II receptor (TGF β RII) mutation in gastric lymphoma without mutator phenotype. Pathol Int 1998, 48:134-137
23. Van Krieken JH, Medeiros LJ, Pals ST, Raffeld M, Kluin PM: Diffuse aggressive B-cell lymphomas of the gastrointestinal tract: an immunophenotypic and gene rearrangement analysis of 22 cases. Am J Clin Pathol 1992, 97:170-178
24. Peng H, Diss T, Isaacson PG, Pan L: c-myc gene abnormalities in mucosa-associated lymphoid tissue (MALT) lymphomas. J Pathol 1997, 181:381-386
25. Diaz JI, Edinger MG, Stoler M, Tubbs RR: Host tumor infiltrating lymphocytes in B cell non-Hodgkin's lymphomas, Leuk Lymphoma 1993, 9:85-90
26. Diaz J, Tubbs R, Stoler M, Grogan T: Cytolytic (TIA-1+) tumor infiltrating lymphocytes in B cell non-Hodgkin's lymphomas. Leuk Lymphoma 1993, 9:91-94
27. Leger-Ravet MB, Devergne O, Peuchmaur M, Solal-Celigny P, Brousse N, Gaulard P, Galanaud P, Emilie D: In situ detection of activated cytotoxic cells in follicular lymphomas. Am J Pathol 1994, 144:492-499
28. Blaser MJ, Parsonnet J: Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J Clin Invest 1994, 94:4-8
29. Bodger K, Wyatt JI, Heatley RV: Gastric mucosal secretion of interleukin-10: relations to histopathology, Helicobacter pylori status, and tumor necrosis factor-α secretion. Gut 1997, 40:739-744
30. Vyth-Dreese, Boot H, Dellemijn TAM, Majoor DM, Oomen LCJM, Laman JD, Van Meurs M, De Weger RA, De Jong D: Localization in situ of costimulatory molecules and cytokines in B-cell non-Hodgkin's lymphoma. Immunology 1998, 94: 580-586
31. Cohen MC, Cohen S: Cytokine function: a study in biologic diversity. Am J Clin Pathol 1996, 105:589-598
32. Shirai M, Arichi T, Nakazawa T, Berzofsky JA: Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection. J Infect Dis 1998, 177: 72-80
33. Kos FJ, Engleman EG: Immune regulation: a critical link between NK cells and CTLs. Immunol Today 1996, 17:174-176
34. Horwitz DA, Gray JD, Ohtsuka K, Hirokawa M, Takahashi T: The immunoregulatory effects of NK cells: the role of TGF-β and implications for autoimmunity. Immunol Today 1997, 18:538-542