Detection of frame-shifts within homopolymeric DNA tracts using the amplification refractory mutation system (ARMS)

BioTechniques

Volumn 27, Issue 4, 1999, Pages 662-666

  Graack, Hanns Rüdiger ^a   Kress, Horst ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TAQ POLYMERASE;

ARTICLE; CONCENTRATION RESPONSE; DNA FLANKING REGION; DNA REPLICATION; FRAMESHIFT MUTATION; GENE AMPLIFICATION; MELTING POINT; MUTATION RATE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS;

EID: 0032883287     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/99274bm06     Document Type: Article

References (6)

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3. Helland, A., F. Karlsen, E.U. Due, R. Holm, G. Kristensen and A.I. Borresen-Dale. 1998. Mutations in the TP53 gene and protein expression of p53, MDM 2 and p21/WAF-1 in primary cervical carcinomas with no or low human papillomavirus load. Br. J. Cancer 78:69-72.
4. Pogue, R., S. West and K. Bushby. 1998. Multiplex SSCP and heteroduplex analysis with Southern hybridization for large-scale mutation detection. Genomics 15:1-4.
5. Sarker, G., J. Cassady, C.D.K. Bottema and S.S. Sommer. 1990. Characterization of polymerase chain reaction amplification of specific alleles. Anal. Biochem. 186:64-68.
6. van Orsouw, N.J., R.K. Dhanda, R.D. Rines, W.M. Smith, I. Sigalas, C. Eng and J. Vijg. 1998. Rapid design of denaturing gradient-based two-dimensional electrophoretic gene mutational scanning tests. Nucleic Acids Res. 26:2398-2406.