Localization of mariner DNA transposons in the human genome by PRINS

Genome Research

Volumn 9, Issue 9, 1999, Pages 839-843

  Reiter, Lawrence T ^a   Liehr, Thomas ^b   Rautenstrauss, Bernd ^c   Robertson, Hugh M ^d   Lupski, James R ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Inst Humangenetik und Anthropologie   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; PRIMER DNA;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; DNA DETERMINATION; DNA STRAND BREAKAGE; FEMALE; GENE LOCATION; GENE LOCUS; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC DISORDER; GENETIC RECOMBINATION; GENOME; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN CELL; MALE; NUCLEOTIDE SEQUENCE; PRIMED IN SITU LABELING; PRIORITY JOURNAL; TECHNIQUE; TRANSPOSON;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 17; DATABASES, FACTUAL; DNA TRANSPOSABLE ELEMENTS; DNA-BINDING PROTEINS; FEMALE; GENOME, HUMAN; HUMANS; LYMPHOCYTES; PRIMED IN SITU LABELING; TRANSPOSASES; X CHROMOSOME;

EID: 0032879002     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.9.9.839     Document Type: Article

References (18)

1. Chance, P.F., N. Abbas, M.W. Lensch, L. Pentao, B.B. Roa, P.I. Patel, and J.R. Lupski. 1994. Two autosomal dominant neuropathies result from reciprocal DNA duplication/deletion of a region on chromosome 17. Hum. Mot. Genet. 3: 223-228.
2. Chen, K.-S., P. Manian, T. Koeuth, L. Potocki, Q. Zhao, A.C. Chinault, C.C. Lee, and J.R. Lupski. 1997. Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome. Nut. Genet. 17: 154-163.
3. Christian, S.L., W.P. Robinson, B. Huang, A. Mutirangura, M.R. Line, M. Nakao, U. Surti, A. Chakravarti, and D.H. Ledbetter. 1995. Molecular characterization of two proximal deletion breakpoint regions in both Prader-Willi and Angelman syndrome patients. Am. J. Hum. Genet. 57: 40-48.
4. Eichler, E.E., M.L. Budarf, M. Rocchi, L.L. Deaven, N.A. Doggett, A. Baldini, D.L. Nelson, and H.W. Mohrenweiser. 1997. Interchromosomal duplications of the adrenolcukodystrophy locus: A phenomenon of pericentromeric plasticity. Hum. Mol. Genet. 6: 991-1002.
5. Heng, H.H.Q. and L.-C. Tsui. 1993. Modes of DAPI handing and simultaneous in situ hybridization. Chromosoma 102: 325-332.
6. Kazazian, H.H., Jr. and J.V. Moran. 1998. The impact of L1 retrotransposons on the human genome. Nat. Genet. 19: 19-24.
7. Kiyosawa, H. and P.F. Chance. 1996. Primate origin of the CMT1A-REP repeat and analysis of a putative transposon-associated recombinational hotspot. Hum. Mol. Genet. 5: 745-753.
8. Luke, S. and M. Shepelsky. 1998. FISH: Recent advances and diagnostic aspects. Cell Vision 5: 49-53.
9. Lupski, J.R. 1998. Genomic disorders: Structural features of the genome can lead to DNA rearrangements and human disease traits. Trends Genet. 14: 417-422.
10. Oosumi, T., W.R. Belknap, and B. Garlick. 1995. Mariner transposons in humans. Nature 378: 672.
11. Pentao, L., C.A. Wise, A.C. Chinault, P.I. Patel, and J.R. Lupski. 1992. Charcot-Marie-Tooth type 1A duplication appears to arise from recombination at repeat sequences flanking the 1.5 Mb monomer unit. Nat. Genet. 2: 292-300.
12. Pérez Jurado, L.A., Y.K. Wang, R. Peoples, A. Coloma, J. Cruces, and U. Francke. 1998. A duplicated gene in the breakpoint regions of the 7q11.23 Williams-Beuren syndrome deletion encodes the initiator binding protein TFII-I and BAP-135, a phosphorylation target of BTK. Hum. Mol. Genet. 7: 325-334.
13. Reiter, L.T., T. Murakami, T. Koeuth, L. Pentao, D.M. Muzny, R.A. Gibbs, and J.R. Lupski. 1996. A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element. Nat. Genet. 12: 288-297.
14. Reiter, L.T., T. Murakami, T. Koeuth, R.A. Gibbs, and J.R. Lupski. 1997. The human COX10 gene is disrupted during homologous recombination between the 24 Kb proximal and distal CMT1A-REPs. Hum. Mol. Genet. 6: 1595-1603.
15. Reiter, L., P.J. Hastings, E. Nelis, P. De Jonhge, C. Van Broekhoven, and J.R. Lupski. 1998. Human meiotic recombination products revealed by sequencing a hotspot for homologous strand exchange in multiple HNPP deletion patients. Am. J. Hum. Genet. 62: 1023-1033.
16. Robertson, H.M. and R. Martos. 1997. Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage. Gene 205: 219-228.
17. Robinson, W.P., F. Dutly, R.D. Nicholls, F. Bernasconi, M. Penaherrera, R.C. Michaelis, D. Abeliovich, and A.A. Schinzel. 1998. The mechanisms involved in formation of deletions and duplications of 15q11-q13. J. Med. Genet. 35: 130-136.
18. Urban, Z., C. Helms, G. Fekete, K. Csiszsár, D. Bonnet, A. Munnich, H. Donis-Keller, and C.D. Boyd. 1996. 7q11.23 deletions in Williams syndrome arise as a consequence of unequal meiotic crossover. Am. J. Hum. Genet. 59: 958-962.