Characteristic loss of heterozygosity in chromosome 3P and low frequency of replication errors in sporadic renal cell carcinoma

Journal of Urology

Volumn 162, Issue 2, 1999, Pages 614-618

  Chino, Kenji ^a   Esumi, Mariko ^a   Ishida, Hajime ^a   Okada, Kiyoki ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chromosome 3p; Loss of heterozygosity; Microsatellite; Renal cell carcinoma; Replication error

Indexed keywords

MICROSATELLITE DNA; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; CARCINOGENESIS; CHROMOSOME 3P; DNA REPAIR; DNA REPLICATION; GENE FREQUENCY; GENE LOCUS; GENE LOSS; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; KIDNEY CARCINOMA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0032878968     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)68636-3     Document Type: Article

References (22)

1. Zbar, B., Brauch, H., Talmadge, C. and Linehan, M.: Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma. Nature, 327: 721, 1987.
2. Kovacs, G., Erlandsson, R., Boldog, F., Ingvarsson, S., Muller-Brechlin, R., Klein, G. and Sumegi, J.: Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc. Natl. Acad. Sci. USA, 85: 1571, 1988.
3. Bergerheim, U., Nordenskjold, M. and Collins, V. P.: Deletion mapping in human renal cell carcinoma. Cancer Res., 49: 1390, 1989.
4. Yamaguchi, K., Esumi, M., Endoh, H., Shikata, T. and Okada, K.: Loss of heterozygosity in renal cell carcinoma. J. Nihon Univ. Med. Ass., (in Japanese) 50: 334, 1991.
5. Ogawa, O., Kakehi, Y., Ogawa, K., Koshiba, M., Sugiyama, T. and Yoshida, O.: Allelic loss at chromosome 3p characterizes clear cell phenotype of renal cell carcinoma. Cancer Res., 51: 949, 1991.
6. Yamakawa, K., Morita, R., Takahashi, E., Hori, T., Ishikawa, J. and Nakamura, Y.: A detailed mapping of the short arm of chromosome 3 in sporadic renal cell carcinoma. Cancer Res., 51: 4707, 1991.
7. LaForgia, S., Lasota, J., Latif, F., Boghosian-Sell, L., Kastury, K., Ohta, M., Druck, T., Atchison, L., Cannizzaro, L. A., Barnea, G., Schlessinger, J., Modi, W., Kuzmin, I., Tory, K., Zbar, B., Croce, C. M., Lerman, M. and Huebner, K.: Detailed genetic and physical map of the 3p chromosome region surrounding the familial renal cell carcinoma chromosome translocation, t(3;8)(p14.2;q24.1). Cancer Res., 53: 3118, 1993.
8. Ohta, M., Inoue, H., Cotticelli, M. G., Kastury, K., Baffa, R., Palazzo, J., Siprashvili, Z., Mori, M., McCue, P., Druck, T., Croce, C. M. and Huebner, K.: The human FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated translocation breakpoint, is abnormal in digestive tract cancer. Cell, 84: 587, 1996.
9. Anglard, P., Tory, K., Brauch, H., Weiss, G. H., Latif, F., Merino, M. J., Lerman, M. I., Zbar, B. and Linehan, W. M.: Molecular analysis of genetic changes in the origin and development of renal cell carcinoma. Cancer Res., 51: 1071, 1991.
10. van der Hout, A., van der Vlies, P., Wijmenga, C., Li, F. P., Oosterhuis, J. W. and Buys, C. H.: The region of common allelic losses in sporadic renal cell carcinoma is bordered by the loci D3S2 and THRB. Genomics, 11: 537, 1991.
11. Latif, F., Tory, K., Gnarra, J., Yao, M., Duh, F-M., Orcutt, M. L., Stackhouse, T., Kuzmin, I., Modi, W., Geil, L., Schmidt, L., Zhou, F., Li, H., Wei, M. H., Chen, F., Glenn, G., Choyke, P., Walther, M. M., Weng, Y., Duan, D-S. R., Dean, M., Glavac, D., Richards, F. M., Crossey, P. A., Ferguson-Smith, M. A., Paslier, D. L., Chumakov, I., Cohen, D., Chinault, A. C., Maher, E. R., Linehan, W. M., Zbar, B. and Lerman, M. I.: Identification of the von Hippel-Lindau disease tumor suppressor gene. Science, 260: 1317, 1993.
12. Wilhelm, M., Bugert, P., Kenck, C., Staehler, G. and Kovacs, G.: Terminal deletion of chromosome 3p sequences in nonpapillary renal cell carcinomas: a breakpoint cluster between loci D3S1285 and D3S1603. Cancer Res., 55: 5383, 1995.
13. Thibodeau, S. N., Bren, G. and Schaid, D.: Microsatellite instability in cancer of the proximal colon. Science, 260: 816, 1993.
14. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D. and Perucho, M.: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature, 363: 558, 1993.
15. Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Son, L., Lutterbaugh, J., Fan, R. S., Zborowska, E., Kinzler, K. W., Vogelstein, B., Brattain, M. and Willson, J. K. V.: Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science, 268: 1336, 1995.
16. Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K. V., Markowitz, S. D., Kinzler, K. W. and Vogelstein, B.: Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res., 55: 5548, 1995.
17. Rampino, N., Yamamoto, H., Ionov, Y., Li, Y., Sawai, H., Reed, J. C. and Perucho, M.: Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science, 275: 967, 1997.
18. Uchida, T., Wada, C., Wang, C., Egawa, S., Ohtani, H. and Koshiba, K.: Genemic instability of microsatellite repeats and mutations of H-, K-, and N-ras and p53 gene in renal cell carcinoma. Cancer Res., 54: 3682, 1994.
19. Sambrook, J., Fritsch, E. F. and Maniatis, T.: Molecular Cloning: A Laboratory Manual. 2nd ed. New York: Cold Spring Harbor Laboratory Press, 1.21, 1989.
20. Japanese Urological Association, Japanese Pathological Society, Japan Radiological Society: General Rules for Clinical and Pathological Studies on Renal Cell Carcinoma. 2nd ed. Tokyo: Kanehara, p. 77, 1992.
21. Horii, A., Han, H. J., Shimada, M., Yanagisawa, A., Kato, Y., Ohta, H., Yasui, W., Tahara, E. and Nakamura Y.: Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancer. Cancer Res., 54: 3373, 1994.
22. Payne, S. J., Richards, F. M. and Maher, E. R.: A PCR generated Ace I RFLP in the 3'-untranslated region of the von Hippel-Lindau disease (VHL) tumour suppressor gene. Hum. Mol. Genet., 3: 390, 1994.