Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat

Research Communications in Molecular Pathology and Pharmacology

Volumn 103, Issue 3, 1999, Pages 275-294

  Kamata, Katsuo ^a   Hayashi, Tsuyoshi ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 ETHYL 2 HYDROXYIMINO 5 NITRO 3 HEXENAMIDE; ACETYLCHOLINE; ENDOTHELIUM DERIVED RELAXING FACTOR; NITRIC OXIDE DONOR; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; KIDNEY PERFUSION; MALE; MESENTERIC ARTERY; MUSCLE RELAXATION; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; VASODILATATION;

ACETYLCHOLINE; ANIMALS; AORTA; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; MALE; MESENTERIC ARTERIES; METHOXAMINE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NITRATES; NITRIC OXIDE DONORS; NITRITES; NITRO COMPOUNDS; NITROPRUSSIDE; RATS; RATS, WISTAR;

EID: 0032878464     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Abe, H., Yamada, N., Kamata, K., Kuwaki, T., Shimada, M., Osuga, J., Shionoiri, F., Yahagi, N., Kadowaki, T., Tametomo, H., Ishibashi, S., Yazaki, Y. and Makuuchi, M. (1998). Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. J. Clin. Invest. 101: 1784-1788.
2. Abiru, T., Watanabe, Y., Kamata, K. and Kasuya, Y. (1993). Changes in endothelium-dependent relaxation and levels of cyclic nucleotides in the perfused mesenteric arterial bed from streptozotocin-induced diabetic rats. Life Sci. 53: PL7-12.
3. Beckman, J.S., Beckman, T.W., Chen, J., Marshall, P.A. and Freeman, B.A. (1990). Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87: 1620-1624.
4. Berliner, J.A., Territo, M.C., Sevanian A., Ramin, S., Kim, J.Ai., Bamshad, B., Esterson, M. and Fogelman, A.M. (1990). Minimally modified low density lipoprotein stimulates monocyte endothelial interaction. J. Clin. Invest. 85: 1260-1267.
5. Blough, N.V. and Zafiriou, O.C. (1985). Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution. Inorg. Chem. 24: 3502-3504.
6. Bolton, T.B., Lang, R.J. and Takewaki, T. (1984). Mechanisms of actions of noradrenaline and carbachol on smooth muscle of guinea-pig anterior mesenteric artery. J. Physiol. 351: 549-572.
7. Chin, J.H., Azhar, S. and Hoffmann, B.B. (1992). Inactivation of endothelial derived relaxing factor by oxidized lipoproteins. J. Clin. Invest., 89: 10-18.
8. Cohen, R.A. (1993). Dysfunction of vascular endothelium in diabetes mellitus. Circulation 87 (sppl. V): V67-76.
9. Cohen, R.A., Zitnay, K.M., Haudenschild, C.C. and Cunningham, L.D. (1988). Loss of selective endothelial cell vasoactive functions caused by hypercholesterolemia in pig coronary arteries. Circ. Res. 63: 903-910.
10. Darley-Usmar, V.M., Hogg, N., O'leary, V.J., Wilson, M.T. and Moncada, S. (1992). The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein. Free Radical Res. Commun. 17: 9-20.
11. Dubowski, K.M. (1962). An o-toluidine method for body-fluid glucose determination. Clin. Chem., 8: 214-235.
12. Edwards, G., Dora, K.A., Gardener, M.J., Garland, C.J. and Weston, A.H. (1998). K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396: 269-272.
13. Egashira, K., Hirooka, Y., Kuga, T., Mohri, M. and Takeshita, A. (1996). Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary arteriograms. Circulation 94: 130-134.
14. Feletou, M. and Vanhoutte, P.M. (1988). Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Brit. J. Pharmacol. 93: 515-524.
15. Flavahan, N.A. (1992). Atherosclerosis or lipoprotein-induced endothelial dysfunction: potential mechanisms underlying reduction in EDRF/nitric oxide activity. Circulation 85: 1927-1937.
16. Gryglewski, R.J., Palmer, R.M. and Moncada, S. (1986). Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320: 454-456.
17. Hattori, Y., Kawasaki, H., Abe, K. and Kanno, M. (1991). Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta. Amer. J. Physiol. 261: H1086-H1094.
18. Heygate, K.M., Lawrence, I.G., Bennett, M.A. and Thurston, H. (1995). Impaired endothelium-dependent relaxation in isolated resistance arteries of spontaneously diabetic rats. Brit. J. Pharmacol., 116: 3251-3259.
19. Hogg, N., Darley-Usmar, V.M., Graham, A. and Moncada, S. (1993a). Peroxynitrite and atherosclerosis. Biochem. Soc. Trans. 21: 358-362.
20. Hogg, N., Darley-Usmar, V.M., Wilson, M.T. and Moncada, S. (1993b). The oxidation of alpha-tocopherol in human low-density lipoprotein by the simultaneous generation of superoxide and nitric oxide. FEBS Lett., 326: 199-203.
21. Hogg, N., Kalyanaraman, B., Joseph, J., Struck, A. and Parthasarathy, S. (1993c). Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. FEBS Lett. 334: 170-174.
22. Jacob, M., Plane, F. and Bruckdorfer, K.R. (1990). Native and oxidized low-density lipoproteins have different inhibitory effects on endothelium-derived relaxing factor in the rabbit aorta. Brit. J. Pharmacol. 100: 21-26.
23. Kamata, K., Chikada, S., Umeda, U. and Kasuya, Y. (1995). Effects of phorbol ester on vasodilatation induced by endothelium-dependent or endothelium-independent vasodilators in the mesenteric arterial bed. J.Cardiovasc. Pharmacol. 26: 645-652.
24. Kamata, K. and Hosokawa, M. (1997). Endothelial dysfunction in the perfused kidney from the streptozotocin-induced diabetic rat. Res. Commun. Mol. Pathol. Pharmacol. 96: 57-70.
25. Kamata, K. and Kobayashi, T. (1996). Changes in superoxide dismutase mRNA expression by streptozotocin-induced diabetes. Brit. J. Pharmacol. 119: 583-589.
26. Kamata, K., Miyata, N. and Kasuya, Y. 1989a. Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats. Brit. J. Pharmacol. 97: 614-618.
27. Kamata, K., Miyata, N. and Kasuya, Y. (1989b). Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats. J. Pharmacol. Exp. Ther. 249: 890-894.
28. Kamata, K., Mori, T., Shigenobu, K. and Kasuya, Y. (1989c). Endothelium-dependent vasodilator effects of platelet activating factor on rat resistance vessels. Brit. J. Pharmacol. 98: 1360-1364.
29. Kamata, K. and Nakajima, M. (1998). Ca2+ mobilization in the aortic endothelium in streptozotocin-induced diabetic and cholesterol-fed mice. Brit. J. Pharmacol. 123: 1509-1516.
30. Kamata, K., Numazawa, T. and Kasuya, Y. (1996a). Characteristics of vasodilatation induced by acetylcholine and platelet-activating factor in the rat mesenteric arterial bed. Eur. J. Pharmacol. 298: 129-136.
31. Kamata, K., Umeda, F. and Kasuya, Y. (1996b). Possible existence of novel endothelium-derived relaxing factor in the endothelium of rat mesenteric arterial bed. J. Cardiovasc. Pharmacol. 27: 601-606.
32. Kita, Y., Hirasawa, Y., Maeda, K., Nishio, M. and Yoshida, K. (1994a). Spontaneous nitric oxide release accounts for the potent pharmacological actions of FK409. Eur. J. Pharmacol. 257: 123-130.
33. Kita, Y., Ozaki, R., Sakai, S., Sugimoto, T., Hirasawa, Y., Ohtsuka, M., Senoh, H., Yoshida, K. and Maeda, K. (1994b). Antianginal effects of FK409, a new spontaneous NO releaser. Brit. J. Pharmacol. 113: 1137-1140.
34. Komori, K. and Suzuki, H. (1987). Electrical responses of smooth muscle cells during cholinergic vasodilation in the rabbit saphenous artery. Circ. Res. 61: 586-593.
35. Kugiyama, K., Kerns, S.A., Morrisett, J.D., Robert, R. and Henry, P.D. (1990). Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature 344: 160-162.
36. Langenstroer, P. and Pieper, G.M. (1992). Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Amer. J. Physiol. 263: H257-H265.
37. Lopez, J.A., Armstrong, M.L., Harrison, D.G., Piegors, D.J. and Heistad, D.D. (1989). Vascular responses to leukocyte products in atherosclerotic primates. Circ. Res. 65: 1078-1086.
38. Mcgregor, D.D. (1965). The effect of sympathetic nerve stimulation on vasoconstrictor response in perfused mesenteric blood vessels of the rat. J. Physiol. 177: 21-30.
39. Ohara, Y., Peterson, T.E. and Harrison, D.G. (1993). Hypercholesterolemia increases endothelial superoxide anion production. J. Clin. Invest. 91: 2546-2551.
40. Oyama, Y., Kawasaki, H., Hattori, Y. and Kanno, M. (1986). Attenuation of endothelium-dependent relaxation in aorta from diabetic rats. Eur. J. Pharmacol. 132: 75-78.
41. Pieper, G.M. (1998). Review of alterations in endothelial nitric oxide production in diabetes. Protective role of arginine on endothelial dysfunction. Hypertension 31: 1047-1060.
42. Pieper, G.M. and Gross, G.J. (1988). Oxygen free radical abolish endothelium-dependent relaxation in diabetic rat aorta. Amer. J. Physiol. 255: H825-H833.
43. Poston, L. and Taylor, P.D. (1995). Endothelium-mediated vascular function in insulin-dependent diabetes mellitus. Clin. Sci. 88: 245-255.
44. Quin, M.T., Parthasarathy, S., Fong, L.G. and Steinberg, D. (1987). Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc. Natl. Acad. Sci. USA, 84: 2995-2998.
45. Radi, R., Beckman, J.S., Bush, K.M. and Freeman, B.A. (1991). Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288: 481-487.
46. Rajavashisth, T.A., Andalibi, A., Territo, M.C., Berliner, J.A., Navab, M., Fogelman, A. and Lusis, A.J. (1990). Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature 344: 254-257.
47. Rubanyi, G.M. and Vanhoutte, P.M. (1986). Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Amer. J. Physiol. 250: H822-H827.
48. Sibata, S., Satake, N., Sato, N., Matsuo, M., Koibuchi, Y. and Hester, R.K. (1991). Characteristics of vasorelaxing action of (3E)-4-ethyl-2-hydroximino-5-nitro-3 hexamiede FK409, a new vasodilator isolated from microbial sources in isolated rabbit arteries. J. Cardiovasc. Pharmacol. 17: 508-518.
49. Simon, B.C., Cunningham, L.D. and Cohen, R.A. (1990). Oxidized low density lipoprotein inhibit endothelium-dependent relaxations in the pig coronary artery. J. Clin. Invest. 86: 75-79.
50. Steinbrecher, U.P., Parthasarrathy, S., Leake, D.S., Witztum, J.L. and Steinberg, D. (1984). Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc. Natl. Acad. Sci. USA 81: 3883-3887.
51. Witztum, J.L. and Steinber, G. D. (1991). Role of oxidized low density lipoprotein in atherosclerosis. J. Clin. Invest. 88: 1785-1792.
52. Yamada, K. and Nabeshima, T. (1997). Simultaneous measurement of nitrite and nitrate levels as indices of nitric oxide release in the cerebellum of conscious rats. J. Neurochem. 68: 1234-1243.
53. Yamada, H., Yoneyama, F., Satoh, K. and Taira, N. (1991). Cardiohemodynamic effect of FK409, a novel highly potent nitro-vasodilator in anesthetized dogs. Brit. J. Pharmacol. 205, 81-83.
54. Yates, M.T., Lambert, L.E., Whitten, J.P., Mcdonald, I., Mano, M., Ku, G.and Mao, S.J. (1992). A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages. FEBS Lett. 309: 135-138.
55. Yokoyama, M., Hirata, K., Miyake, R., Akita, H., Ishikawa, Y. and Fukuzaki, H. (1990). Lysophosphoatidylcholine: essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low-density lipoprotein. Biochem. Biophys. Res. Commun. 168: 301-308.