Determination of a novel calmodulin antagonist, 3-{2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl}-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate, DY-9760e, in human plasma using solid-phase extraction and high-performance liquid chromatography with fluorescence detection

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 734, Issue 1, 1999, Pages 39-45

  Tachibana, Shuko ^a   Fukano, Aiko ^a   Sudo, Ken Ichi ^a   Tanaka, Makoto ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Calmodulin antagonist; DY 9760e; DY 9836

Indexed keywords

3 [2 [4 (3 CHLORO 2 METHYLPHENYL) 1 PIPERAZINYL]ETHYL] 5,6 DIMETHOXY 1 (4 IMIDAZOLYLMETHYL) 1H INDAZOLE; 3 [2 [4 (3 CHLORO 2 METHYLPHENYL) 1 PIPERAZINYL]ETHYL] 5,6 DIMETHOXYINDAZOLE; CALMODULIN INHIBITOR; DY 9695; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STABILITY; FLUORESCENCE; HUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION;

BUFFERS; CALMODULIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; INDAZOLES; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; SOLUTIONS; SPECTROMETRY, FLUORESCENCE;

EID: 0032878027     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00329-1     Document Type: Article

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