Molecular cloning, tissue-specific expression, and chromosomal localization of a novel nerve growth factor-regulated G-protein-coupled receptor, nrg-1

Molecular and Cellular Neurosciences

Volumn 14, Issue 2, 1999, Pages 141-152

  Glickman, Michelle ^a   Malek, Renae L ^a   Kwitek Black, Anne E ^b   Jacob, Howard J ^b   Lee, Norman H ^a  

^a J CRAIG VENTER INSTITUTE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; NERVE GROWTH FACTOR RECEPTOR;

ANIMAL TISSUE; ARTICLE; CHROMOSOME MAP; DNA LIBRARY; GENE EXPRESSION REGULATION; GENE LOCATION; MOLECULAR CLONING; MULTIGENE FAMILY; NERVE CELL DIFFERENTIATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RECEPTOR GENE; SEQUENCE ANALYSIS; UNINDEXED SEQUENCE;

EID: 0032877398     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1999.0776     Document Type: Article

References (34)

1. Adams M. D., Kerlavage A. R., Fleischmann R. D., Fuldner R. A., Bult C. J., Lee N. H., Kirkness E. F., Weinstock K. G., Gocayne J. D., White O., Sutton G., Blake J. A., Brandon R. C., Chiu M. W., Clayton R. A., Cline R. T., Cotton M. D., Earle-Hughes J., Fine L. D., FitzGerald L. M., FitzHugh W. M., Fritchman J. L., Geoghagen N. S. M., Glodek A., Gnehm C. L., Hanna M. C., Hedblom E., Hinkle P. S. Jr., Kelley J. M., Klimek K. M., Kelley J. C., Liu L.-I., Marmaros S. M., Merrick J. M., Moreno-Palanques R. F., McDonald L. A., Nguyen D. T., Pellegrino S. M., Phillips C. A., Ryder S. E., Scott J. L., Saudek D. M., Shirley R., Small K. V., Spriggs T. A., Utterback T. R., Weidman J. F., Li Y., Barthlow R., Bednarik D. P., Cao L., Cepeda M. A., Coleman T. A., Collins E.-J., Dimke D., Feng P., Ferrie A., Fischer C., Hastings G. A., He W.-W., Hu J.-S., Huddleston K. A., Greene J. M., Gruber J., Hudson P., Kim A., Kozak D. L., Kunsch C., Ji H., Li H., Meissner P. S., Olsen H., Raymond L., Wei Y.-F., Wing J., Xu C., Yu G.-L., Ruben S. M., Dillon P. J., Fannon M. R., Rosen C. A., Haseltine W. A., Fields C., Fraser C. M., Venter J. C. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Nature. 377:1995;3-174.
2. An S., Bleu T., Hallmark O. G., Goetzl E. J. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid. J. Biol. Chem. 273:1998;7906-7910.
3. An S., Bleu T., Huang W., Hallmark O. G., Coughlin S. R., Goetzl E. J. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids. FEBS Lett. 417:1997a;279-282.
4. An S., Dickens M. A., Bleu T., Hallmark O. G., Goetzl E. J. Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid. Biochem. Biophys. Res. Commun. 231:1997b;619-622.
5. Atwater J. A., Wisdom R., Verma I. M. Regulated mRNA stability. Annu. Rev. Genet. 24:1994;519-541.
6. Audic S., Claverie J.-M. The significance of digital gene expression profiles. Genome Res. 7:1997;986-995.
7. Cavallaro S., D'Agata V., Guardabasso V., Travali S., Stivala F., Canonico P. L. Differentiation induces pituitary adenylate cyclase-activating polypeptide receptor expression in PC-12 cells. Mol. Pharmacol. 48:1995;56-62.
8. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;152-159.
9. Fraser C. M., Lee N. H., Pellegrino S. M., Kerlavage A. R. Molecular properties and regulation of G-protein-coupled receptors. Prog. Nucleic Acids Res. Mol. Biol. 49:1994;113-156.
10. Frodin M., Peraldi P., van Obberghen E. Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells. J. Biol. Chem. 269:1994;6207-6214.
11. Ginty D. D., Glowacka D., DeFranco C., Wagner J. A. Nerve growth factor-induced neuronal differentiation after dominant repression of both type I and type II cAMP-dependent protein kinase activities. J. Biol. Chem. 266:1991;15325-15333.
12. Goetzl E. J., An S. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J. 12:1998;1589-1598.
13. Guroff G., Dickens G., End D., Londos C. The action of adenosine analogs on PC12 cells. J. Neurochem. 37:1981;1431-1439.
14. Halegoua S., Armstrong R. C., Kremer N. E. Dissecting the mode of action of a neuronal growth factor. Curr. Top. Microbiol. Immunol. 165:1991;119-170.
15. Heasley L. E., Johnson G. L. The β-PDGF receptor induces neuronal differentiation of PC12 cells. Mol. Biol. Cell. 3:1992;545-553.
16. Kozak M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell. 44:1986;283-292.
17. Kyte J., Doolittle R. F. A simple method for displaying the hydrophobic character of a protein. J. Mol. Biol. 157:1982;105-132.
18. Lado D. C., Browe C. S., Gaskin A. A., Borden J. M., MacLennan A. J. Cloning of the rat edg-1 immediate-early gene: Expression pattern suggests diverse functions. Gene. 149:1994;331-336.
19. Lee M.-J., Van Brocklyn J. R., Thangada S., Lui C. H., Hand A. R., Menzeleev R., Spiegel S., Hla T. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science. 279:1998;1552-1555.
20. Lee N. H. Regulation of PLC coupled receptor mRNA stability. Tobin A. The Phosphoinositidase C Pathway: Its Regulation and Desensitization. 1996;133-158 R. G. Landes, Austin.
21. Lee N. H., Fraser C. M. Cross-talk between m1 muscarinic acetylcholine and β2-adrenergic receptors. cAMP and the third intracellular loop of m1 muscarinic receptors confer heterologous regulation. J. Biol. Chem. 268:1993;7949-7957.
22. Lee N. H., Geoghagen N. S. M., Cheng E., Cline R. T., Fraser, C. M. Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors. Mol. Pharmacol. 50:1996;140-148.
23. Lee N. H., Malek R. L. Nerve growth factor regulation of m4 muscarinic receptor mNRA stability but not gene transcription requires mitogen-activated protein kinase activity. J. Biol. Chem. 273:1998;22317-22325.
24. Lee N. H., Weinstock K. G., Kirkness E. F., Earle-Hughes J. A., Fuldner R. A., Marmaras S., Glodek A., Gocayne J. D., Fraser C. M., Venter J. C. Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC12 cells before and after nerve growth factor treatment. Proc. Natl. Acad. Sci. USA. 92:1995;8303-8307.
25. MacLennan A. J., Browe C. S., Gaskin A. A., Lado D. C., Shaw G. Cloning and characterization of a putative G-protein coupled receptor potentially involved in development. Mol. Cell. Neurosci. 5:1994;201-209.
26. Moolenaar W. H., Kranenburg O., Postma F. R., Zondag G. C. M. Curr. Opin. Cell Biol. 9:1997;168-173.
27. Nishizawa K. NGF-induced stabilization of GAP-43 mRNA is mediated by both 3′ untranslated region and a segment encoding the carboxy-terminus peptide. Biochem. Biophys. Res. Commun. 200:1994;789-795.
28. Perrone-Bizzozero N. I., Cansino V. V., Kohn D. T. Posttranscriptional regulation of GAP-43 gene expression in PC12 cells through protein kinase C-dependent stabilization of the mRNA. J. Cell Biol. 120:1993;1263-1270.
29. Rands E., Candelore M. R., Cheung A. H., Hill W. S., Strader C. D., Dixon R. A. F. Mutational analysis of beta-adrenergic receptor glycosylation. J. Biol. Chem. 265:1990;10759-10764.
30. Slonim D., Kruglyak L., Stein L., Lander E. Building human genome maps with radiation hybrids. J. Comput. Biol. 4:1997;487-504.
31. Traverse S., Seedorf K., Paterson H., Marshall C. J., Cohen P., Ullrich A. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr. Biol. 4:1994;694-701.
32. Weinstock K. G., Kirkness E. F., Lee N. H., Earle-Hughes J. A., Venter J. C. cDNA sequencing: A means of understanding cellular physiology. Curr. Opin. Biotech. 5:1994;599-603.
33. Yamaguchi F., Tokuda M., Hatase O., Brenner S. Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9. Biochem. Biophys. Res. Commun. 227:1996;608-614.
34. Yao H., York R. D., Misra-Press A., Carr D. W., Stork P. J. S. The cyclic adenosine monophosphate-dependent protein kinase A (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor. J. Biol. Chem. 273:1998;8240-8247.