Principal component analysis of tissue scores from substances used in the COLIPA Eye Irritation Validation Study

Toxicology in Vitro

Volumn 13, Issue 3, 1999, Pages 491-503

  Lovell, D P ^a  

^a BIBRA INTERNATIONAL   (United Kingdom)

Author keywords

Cosmetic formulations; Draize eye scores; Multivariate analysis; Principal component analysis

Indexed keywords

ACETIC ACID ETHYL ESTER; BENZALKONIUM CHLORIDE; CETYLPYRIDINIUM SALT; COSMETIC; DODECYL SULFATE SODIUM; FLUORESCEIN; GLYCEROL; HAIR DYE; IMIDAZOLE; POLYSORBATE 20; PROPYLENE GLYCOL; SHAMPOO; SOAP; SODIUM HYDROXIDE; SUNSCREEN; TRICHLOROACETIC ACID; TRITON X 100;

ARTICLE; BIOLOGICAL MODEL; CORNEA OPACITY; DATA BASE; EYE INJURY; EYE IRRITATION; MULTIVARIATE ANALYSIS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; TISSUE; TISSUE INJURY;

EID: 0032875977     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(99)00010-7     Document Type: Article

References (9)

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7. Lovell D.P. Principal component analysis of Draize eye irritation tissue scores from 72 samples of 55 chemicals in the ECETOC data bank. Toxicology in Vitro. 10:1996;609-618.
8. Lovell D. P. (1997) Use of Principal Component Analysis for Draize Eye Irritation Tissue Scores. 2nd World Congress on Alternatives and Animal Use in the Life Sciences. ed. B. Van Zutphen. Elsevier, Amsterdam.
9. OECD (1987) OECD Guidelines for Testing of Chemicals: Test Guideline 405, Acute Eye Irritation/Corrosion, Organisation for Economic Cooperation and Development, adopted 24 February 1987.