Intranasal IFN-γ gene transfer protects BALB/c mice against respiratory syncytial virus infection

Vaccine

Volumn 18, Issue 5-6, 1999, Pages 558-567

  Kumar, Mukesh ^a   Behera, Aruna K ^a   Matsuse, Hiroto ^a   Lockey, Richard F ^a   Mohapatra, Shyam S ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cytokine; Gene transfer; RSV

Indexed keywords

GAMMA INTERFERON; PLASMID DNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; INTRANASAL DRUG ADMINISTRATION; LUNG; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; TECHNIQUE; VIRUS INFECTION; VIRUS REPLICATION;

ADMINISTRATION, INTRANASAL; ANIMALS; FEMALE; GENE TRANSFER TECHNIQUES; INTERFERON TYPE II; INTERLEUKIN-5; LUNG; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RNA, MESSENGER; VIRUS REPLICATION;

EID: 0032874043     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(99)00185-1     Document Type: Article

References (39)

1. Chanock R.M., Parott R.H. Acute respiratory disease in infancy and childhood: present understanding and prospects for prevention. Pediatrics. 36:1981;21-39.
2. Brandt C.D., Kim H.W., Arrobio J.O., et al. Epidemiology of respiratory syncytial virus infection in Washington, DC. III. Composite analysis of eleven consecutive yearly epidemics. Am. J. Epidemiol. 98:1990;355-364.
3. Kim H.W., Arrobio J.O., Brandt C.D., et al. Epidemiology of respiratory syncytial virus infection in Washington, DC. I. Importance of the virus in different respiratory tract disease syndromes and temporal distribution of infection. Am. J. Epidemiol. 98:1973;216-225.
4. McIntosh K., Chanock R.M. Respiratory Syncytia Virus. Fields B.N., Knipe D.M. Virology. 2 :1990;1045.
5. Murray A.R., Dowell S.F. Respiratory syncytial virus: not just for kids. Hospital Practice. 15:1997;87-104.
6. Respiratory syncytial virus activity 1996-1997 season. MMWR. 45:1996;1053.
7. Hall C.B., McBride J.T. Respiratory syncytial virus-from chimps with colds to conundrums and cures. New. Engl. J. Med. 325:1991;57-58.
8. Warren K.S. New scientific opportunities and old obstacles in vaccine development. Proc. Natl. Acad. Sci. USA. 83:1986;9275-9277.
9. Walsh J. Establishing health priorities in the developing world. 1988;United Nations Development Programme, New York.
10. Hall C.B., Walsh E.E., Long C.E., Schnabel K.C. Immunity to and frequency of reinfection with respiratory syncytial virus. J. Infect. Dis. 163:1991;693-698.
11. Chanock R.M., Parrott R.H., Connors M., Collins P.L., Murphy B.R. Serious respiratory tract disease caused by respiratory syncytial virus: prospects for improved therapy and immunization. Pediatrics. 90:1992;137-143.
12. Hall C.B. Prospects for a respiratory syncytial virus vaccine. Science. 265:1994;1393-1394.
13. Mok J.Y.K., Simpson H. Symptoms, atopy and bronchial reactivity after lower respiratory infection in children. Arch. Dis. Child. 59:1984;299-305.
14. Weiss S.T., Tager I.B., Munoz A., Speizer F.E. The relationship of respiratory infection in early childhood to the occurrence of increased levels of bronchial responsiveness and atopy. Am. Rev. Res. Dis. 131:1985;573-578.
15. Sly P.D., Hibbert M.E. Childhood asthma following hospitalization with acute viral bronchiolitis in infancy. Pediatr. Pulmonol. 7:1989;153-158.
16. Schwarze J., Hamelmann E., Bradley K.L., Takeda K., Gelfand E.W. Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen. J. Clin. Invest. 100:1997;226-233.
17. Mosmann T.R., Coffman R.I. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:1989;145-173.
18. Roman M., Calhoun W.J., Hinton K.L., Avendano L.F., Simon V., Escobar A.M., Gaggero A., Diaz P.V. Respiratory syncytial virus infection in infants is associated with predominant Th-2-like response. Am. J. Resp. Crit. Care Med. 156:1997;190-195.
19. Connors M., Kulkarni A.B., Firestone C.Y., Holmes K.L., Morse H.C., Sotnikov A.V., Murphy B.R. Pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of CD4+ T cells. J. Virol. 66:1992;7444-7451.
20. Connors M., Geise N.A., Kulkarni A.B., Firestone C.Y., Morse H.C., Sotnikov A.V., Murphy B.R. Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10. J. Virol. 68:1994;5321-5325.
21. Graham B.S., Henderson G.S., Tang Y.W., Lu X., Neuzil K.M., Colley D.G. Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus. J. Immunol. 151:1993;2032-2040.
22. Pene J., Rousset F., Briere F., Chretien I., Bonnefoy J.Y., Spits H., Yokota T., Arai N., Arai K.I., Banchereay J., de Vries J. IgE production by human lymphocytes is induced by interleukin-4 and suppressed by interferons gamma, alpha and prostaglandin E2. Proc. Natl. Acad. Sci. USA. 85:1988;6880-6884.
23. Li X.M., Chopra R.K., Chou T.Y., Schofield B.H., Wills-Karp M., Huang S.K. Mucosal IFN-γ gene transfer inhibits pulmonary allergic responses in mice. J. Immunol. 157:1996;3216-3219.
24. Sethi S.K., Bianco A., Allen J.T., Knight R.A., Spiteri M.A. Interferon-gamma down-regulates the rhinovirus-induced expression of intercellular adhesion molecule-1 (ICAM-1) on human airway epithelial cells. Clin. Exp. Immunol. 110:1997;362-369.
25. Ledley F.D. Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum. Gene Ther. 6:1995;1129-1144.
26. Graham B.S., Perkins M.D., Wright P.F., Karzon D.T. Primary respiratory syncytial virus infection in mice. J. Med. Virol. 26:1988;153-162.
27. Taylor G., Stott E.J., Hughes M., Collins A.P. Respiratory syncytial virus infection in mice. Infect. Immun. 43:1984;649-655.
28. Tautz D., Renz M. An optimized freeze-squeeze method for the recovery of DNA fragments from agarose gels. Anal. Biochem. 132:1983;14-19.
29. Muller U., Steinhoff U., Reis L.F.L., Hemmi S., Pavlovic J., Zinkernagel R.M., Aguet M. Functional role of type I and type II interferons in antiviral defense. Science. 264:1994;1918-1921.
30. Will A., Hemmann U., Horn F., Rollinghoff M., Gessner A. Intracellular murine IFN-γ mediates virus resistance, expression of oligoadenylate synthetase and activation of STAT transcription factors. J. Immunol. 157:1996;4576-4583.
31. Taylor G., Stott E.J., Hayle A.J. Cytotoxic lymphocytes from the lung of mice infected with respiratory syncytial virus. J. Gen. Virol. 66:1985;2533-2538.
32. Openshaw P.J.M. Flow cytometric analysis of pulmonary lymphocytes from mice infected with respiratory syncytial virus. Clin. Exp. Immunol. 75:1989;324-328.
33. Arnold R., Werchau H., Konig W. Expression of adhesion molecules (ICAM-1 LFA-3) on human epithelial cells (A549) after respiratory syncytial virus infection. Int. Arch. Allergy Immunol. 107:1995;392-393.
34. Matsuzaki Z., Okamoto Y., Sarashina N., Ito E., Togawa K., Saito I. Induction of intercellular adhesion molecule-1 in human nasal epithelial cells during respiratory syncytial virus infection. Immunology. 88:1996;565-568.
35. Arnold R., Konig W. ICAM-1 expression and low-molecular-weight G-protein activation of human bronchial epithelial cells (A549) infected with RSV. J. Leuk. Biol. 60:1996;766-771.
36. Stark J.M., Godding V., Sedgwick J.B., Busse W.W. Respiratory syncytial virus infection enhances neutrophil and eosinophil adhesion to cultured respiratory epithelial cells. Roles of CD18 and intercellular adhesion molecule-1. J. Immunol. 156:1996;4774-4782.
37. Chonomaitre T., Roberts N.J., Douglas R.G., Hall C.B., Simons R.L. Interferon production by human mononuclear leukocytes: differences between respiratory syncytial virus and influenza virus. Infect. Immun. 32:1981;300-303.
38. Woolums A.R., Singer R.S., Boyle G.A., Gershwin L.J. Interferon gamma production during bovine respiratory syncytial virus (BRSV) infection is diminished in calves vaccinated with formalin-inactivated BRSV. Vaccine. 17:1999;1293-1297.
39. Bukreyev A., Whitehead S.S., Bukreyeva N., Murphy B.R., Collins P.L. Interferon γ expressed by a recombinant respiratory syncytial virus attenuates virus replication in mice without compromising immunogenicity. Proc. Natl. Acad. Sci. USA. 96:1999;2367-2372.