In vivo methotrexate selection of murine hemopoietic cells transduced with a retroviral vector for Gaucher disease

Gene Therapy

Volumn 6, Issue 10, 1999, Pages 1661-1669

  Havenga, M J E ^a   Valerio, D ^a,b   Hoogerbrugge, P ^c   Van Es, H H G ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CRUCELL HOLLAND BV   (Netherlands)

^c NONE

Author keywords

DHFR; Gaucher disease; Gene therapy; In vivo selection; Retrovirus; Stem cells

Indexed keywords

COMPLEMENTARY DNA; DIHYDROFOLATE REDUCTASE; GLUCOSYLCERAMIDASE; LYSOSOME ENZYME; METHOTREXATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL SELECTION; CONTROLLED STUDY; FEMALE; GAUCHER DISEASE; GENETIC TRANSDUCTION; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS;

ANIMALS; DRUG RESISTANCE; FEMALE; FLOW CYTOMETRY; GAUCHER DISEASE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLUCOSYLCERAMIDASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MALE; METHOTREXATE; MICE; MICE, INBRED CBA; RETROVIRIDAE; TRANSDUCTION, GENETIC; TRANSPLANTATION CONDITIONING;

EID: 0032873191     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301037     Document Type: Article

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