Peripheral steroid sulfatase inhibition potentiates improvement of memory retention for hippocampally administered dehydroepiandrosterone sulfate but not pregnenolone sulfate

Psychoneuroendocrinology

Volumn 24, Issue 8, 1999, Pages 799-811

  Flood, James F ^a,b   Farr, Susan A ^a,b   Johnson, David A ^c   Li, Pui Kai ^c   Morley, John E ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Grad Sch Pharmaceutical Sci   (United States)

Author keywords

Dehydroepiandrosterone sulfate; Memory retention; Peripheral steroid sulfatase; Pregnenolone sulfate

Indexed keywords

ENZYME INHIBITOR; PRASTERONE SULFATE; PREGNENOLONE SULFATE; STERYL SULFATASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; HIPPOCAMPUS; HORMONE BLOOD LEVEL; HORMONE DEPENDENCE; MALE; MAZE TEST; MEMORY CONSOLIDATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARYLSULFATASES; AVOIDANCE LEARNING; BRAIN MAPPING; DEHYDROEPIANDROSTERONE SULFATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; ESTRONE; HIPPOCAMPUS; INJECTIONS; MALE; MAZE LEARNING; MICE; PREGNENOLONE; RETENTION (PSYCHOLOGY); STERYL-SULFATASE;

EID: 0032870870     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4530(99)00030-X     Document Type: Article

References (39)

1. Baulieu E.-E., Robel P. Neurosteroids: a new brain function? J. Steroid Biochem. Mol. Biol. 37:1990;395-403.
2. Bowlby M.R., Kravitz E.A. Pregnenolone sulfate allosterically potentiates the NMDA current in hippocampal neurons. Soc. Neurosci. Abstr. 18:1992;257.
3. Brioni J.D., Nagahara A., McGaugh J.L. Involvement of the amygdala GABAergic system in the modulation of memory storage. Brain Res. 47:1989;105-112.
4. A receptor. Neuroscience. 45:1991;127-135.
5. Flood J.F., Morley J.E. Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM). Neurobiol. Aging. 14:1993;153-157.
6. Flood J.F., Roberts E. Dehydroepiandrosterone sulfate improves memory in aging mice. Brain Res. 448:1988;178-181.
7. Flood J.F., Smith G.E., Roberts E. Dehydroepiandrosterone and its sulfate enhance retention in mice. Brain Res. 447:1988;269-278.
8. Flood J.F., Baker M.L., Davis J.L. Modulation of memory processing by glutamic acid receptor agonists and antagonists. Brain Res. 521:1990;197-202.
9. Flood J.F., Morley J.E., Roberts E. Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it. Proc. Natl. Acad. Sci. USA. 89:1992;1567-1571.
10. Flood J.F., Morley J.E., Roberts E. Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: the amygdala is by far the most sensitive. Proc. Natl. Acad. Sci. USA. 92:1995;10806-10810.
11. Flood J.F., Scherrer J.F., Morley J.E. Localized injections in the mammillary complex enhance retention. Eur. J Pharmacol. 275:1995;223-228.
12. Flood J.F., Harris F.J., Morley J.E. Age-Related changes in hippocampal drug facilitation of memory processing in SAMP8 mice. Neurobiol. Aging. 17:1996;15-24.
13. Howarth N.M., Purobit A., Reed M.J., Potter B.V.L. Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential. J. Med. Chem. 37:1994;219-221.
14. Isaacson R.L., Yoder P.E., Varner J. The effects of pregnenolone on acquisition and retention of a food search task. Behav. Neural Biol. 61:1994;170-176.
15. Isaacson R.L., Varner J., Baars J.M., De Wied D. The effects of pregnenolone sulfate and ethylestrenol on retention of a passive avoidance task. Brain Res. 689:1995;79-84.
16. Iwamori M., Moser H.W., Kishimoto Y. Steroid sulfatase in brain: comparison of sulfohydrolase activities for various steroid sulfates in normal and pathological brains, including the various forms of metachromatic leukodystrophy. J. Neurochem. 27:1976;1389-1395.
17. Izquierdo I., Da Cunha C., Rosat R., Jerusalinsky D., Ferreira M.B.C., Medina J.H. Neurotransmitter receptors involved in post-training memory processing by the amygdala, medial septum, and hippocampus of the rat. Behav. Neural Biol. 58:1992;16-26.
18. Izquierdo I., Bianchin M., Silva M.B.E. et al. CNQX infused into rat hippocampus or amygdala disrupts the expression of two different tasks. Behav. Neural Biol. 59:1993;1-4.
19. Keppel G., Zedeck S. Data Analysis for Research Designs: Analysis of Variance and Multiple Regression/Correlation Approaches. 1989;W.H. Freeman and Company, New York.
20. Lee E.H.Y., Lee C.P., Wang H.I., Lin W.R. Hippocampal CRF, NE, and NMDA system interactions in memory processing in the rat. Synapse. 14:1993;144-153.
21. Li P.-K., Rhodes M.E., Jagannathan S., Johnson D.A. Reversal of scopolamine induced amnesia in rats by the steroid sulfatase inhibitor estrone-3-O-sulfamate. Cogn. Brain Res. 2:1995;251-254.
22. A receptor. Brain Res. 526:1990;143-146.
23. A receptor. Eur. J. Pharmacol. 189:1990;307-315.
24. Mathis C., Vogel E., Cagniard B., Criscuolo F., Ungerer A. The neurosteroid pregnenolone sulfate blocks deficits induced by competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice. Neuropharmacology. 35:1996;1057-1064.
25. Maurice T., Junien J.L., Privat A. Dehyroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors. Behav. Brain Res. 83:1997;159-164.
26. Maurice T., Lockhart B.P. Neuroprotective and anti-amnesic potentials of sigma (s) receptor ligands. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 21:1997;69-102.
27. Mayo W., Dellu F., Robel P. et al. Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat. Brain Res. 607:1993;324-328.
28. McGaugh J.L. Drug facilitation of learning and memory. Annu. Rev. Pharmacol. 13:1973;229-241.
29. Meziane H., Mathis C., Paul S.M., Ungerer A. The neurosteroid pregnenolone sulfate reduces learning deficits induced by scopolamine and has promnestic effects in mice performing an appetitive learning task. Psychopharmacology. 126:1996;323-330.
30. Monnet F.P., Mahé V., Robel P., Baulieu E.-E. Neurosteroids, via s receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus. Proc. Natl. Acad. Sci. USA. 92:1995;3774-3778.
31. Ohno M., Yamamoto T., Watanabe S. Effects of intrahippocampal injections of N-methyl-D-asparate receptor antagonists and scopolamine on working and reference memory assessed in rats by a three-panel runway task. J. Pharmacol. Exp. Ther. 263:1992;943-950.
32. Purohit A., Williams G.J., Roberts C.J., Potter B.V.L., Reed M.J. In vivo inhibition of oestrone sulphatase and dehydroepiandrosterone sulphatase by oestrone-3-O-sulphamate. Int. J. Cancer. 63:1995;106-111.
33. Rédini-Del Negro C., Laroche S. Learning-induced increase in glutamate release in the dentate gyrus is blocked by NMDA receptor antagonist AP5. Neurosci. Res. Commun. 13:1993;157-165.
34. Rhodes M.E., Li P.-K., Flood J.F., Johnson D.A. Enhancement of hippocampal acetylcholine release by the neurosteroid dehydroepiandrosterone sulfate: an in vivo microdialysis study. Brain Res. 733:1996;284-286.
35. Rhodes M.E., Li P.-K., Burke A.M., Johnson D.A. Enhanced plasma DHEAS, brain acetylcholine and memory mediated by steroid sulfatase inhibition. Brain Res. 773:1997;28-32.
36. Slotnick B.M., Leonard C.M. A Stereotaxic Atlas of the Albino Mouse Forebrain. 1975;U.S. Government Printing Office, Washington, DC.
37. Sousa A., Ticku M.K. Interactions of the neurosteroid dehydroepiandrosterone sulfate with the GABA(A) receptor complex reveals that it may act via the picrotoxin site. J. Pharmacol. Exp. Ther. 282:1997;827-833.
38. Steffensen S.C. Dehydroepiandrosterone sulfate suppresses hippocampal recurrent inhibition and synchronizes neuronal activity to theta rhythm. Hippocampus. 5:1995;320-328.
39. Swanson L.W. Brain Maps Computer Graphics Files. 1992;Elsevier Science, Amsterdam.