Investigation of the alveolar macrophages and T lymphocytes in 15 patients with systemic sclerosis

Clinical Rheumatology

Volumn 18, Issue 5, 1999, Pages 357-363

  Czirják, László ^a   Koncz, A ^b   Varga, I ^c   Devenyi K ^d   Kumanovics G ^a   Szucs G ^d  

^a UNIVERSITY OF PÉCS   (Hungary)

^b Kenezy Korhaz Rendelointezet   (Hungary)

^c Dept of Lung and Heart Diseases ^*  (Hungary)

^d UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Alveolar macrophages; Interleukin 6; Scleroderma; Systemic sclerosis; Tumour necrosis factor

Indexed keywords

INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HELPER CELL; HUMAN; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; SYSTEMIC SCLEROSIS; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ADULT; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CHEMOTAXIS; CULTURE MEDIA, CONDITIONED; FEMALE; HUMANS; INTERLEUKIN-6; LUNG DISEASES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MACROPHAGES, ALVEOLAR; MIDDLE AGED; PHAGOCYTOSIS; SCLERODERMA, SYSTEMIC; T-LYMPHOCYTES; TOMOGRAPHY, X-RAY COMPUTED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032869964     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100670050119     Document Type: Article

References (38)

1. Nagy Z, Czirják L. Predictors of survival in 171 patients with systemic sclerosis (scleroderma). Clin Rheumatol 1997;16:454-60.
2. Czirják L, Szolnoki E, Nagy Z, Szegedi G. Changes in pulmonary function in systemic sclerosis [letter]. Postgrad Med J 1992;68:388.
3. Wells AU, Hansell DM, Rubens MB, King AD, Cramer D, Black CM, du Bois RM. Fibrosing alveolitis in systemic sclerosis: indices of lung function in relation to extent of disease on computed tomography. Arthritis Rheum 1997;40:1229-36.
4. Remy Jardin M, Remy J, Wallaert B, Bataille D, Hatron PY. Pulmonary involvement in progressive systemic sclerosis: sequential evaluation with CT, pulmonary function tests, and bronchoalveolar lavage. Radiology 1993;188:499-506.
5. Dévényi K, Czirják L. High resolution computed tomography for the evaluation of lung involvement in 101 patients with scleroderma. Clin Rheumatol 1995;14:633-40.
6. Harrison NK, Glanville AR, Strickland B, Haslam PL, Corrin B, Addis BJ, et al. Pulmonary involvement in systemic sclerosis: the detection of early changes by thin section CT scan, bronchoalveolar lavage and 99mTc-DTPA clearance. Respir Med 1989;83:403-14.
7. Wells AU, Hansell DM, Rubens MB, Cullinan P, Haslam PL, Black CM, du Bois RM. Fibrosing alveolitis in systemic sclerosis. Bronchoalveolar lavage findings in relation to computed tomographic appearance. Am J Respir Crit Care Med 1994;150:462-8.
8. Wells AU, Hansell DM, Corrin B, Harrison NK, Goldstraw P, Black CM, du Bois RM. High resolution computed tomography as a predictor of lung histology in systemic sclerosis. Thorax 1992;47:738-42.
9. Frigieri L, Mormile F, Grilli N, Mancini D, Ciappi G, Pagliari G, et al. Bilateral bronchoalveolar lavage in progressive systemic sclerosis, interlobar variability, lymphocyte subpopulations, and functional correlations. Respiration 1991;58:132-40.
10. Wallaert B, Dugas M, Dansin E, Perez T, Marquette CH, Ramon P, et al. Subclinical alveolitis in immunological systemic disorders. Transition between health and disease? Eur Respir J 1990;3:1206-16.
11. Crestani B, Seta N, De Bandt M, Soler P, Rolland C, Dehoux M, et al. Interleukin 6 secretion by monocytes and alveolar macrophages in systemic sclerosis with lung involvement. Am J Respir Crit Care Med 1994;149:1260-65.
12. Silver RM, Miller KS, Kinsella MB, Smith EA, Schabel SI. Evaluation and management of scleroderma lung disease using bronchoalveolar lavage. Am J Med 1990;88:470-6.
13. Warrick JH, Bhalla M, Schabel SI, Silver RM. High resolution computed tomography in early scleroderma lung disease. J Rheumatol 1991;18:1520-8.
14. Csipõ I, Czirják L, Szántó S, Szerafin L, Sipka S, Szegedi G. Decreased serum tryptophan and elevated neopterin levels in systemic sclerosis [letter]. Clin Exp Rheumatol 1995;13:269-70.
15. Szegedi A, Czirják L, Unkeless JC, Boros P. Serum cytokine and anti-Fc gamma R autoantibody measurements in patients with systemic sclerosis. Acta Derm Venereol 1996;76:21-3.
16. Mavalia C, Scaletti C, Romagnani P, Carossino AM, Pignone A, Emmi L, et al. Type 2 helper T-cell predominance and high CD30 expression in systemic sclerosis. Am J Pathol 1997;151:1751-8.
17. Yurovsky VV, Wigley FM, Wise RA, White B. Skewing of the CD8+ T-cell repertoire in the lungs of patients with systemic sclerosis. Hum Immunol 1996;48:84-97.
18. Gudbjornsson B, Hallgren R, Nettelbladt O, Gustafsson R, Mattsson A, Geijerstam E, Totterman TH. Phenotypic and functional activation of alveolar macrophages, T lymphocytes and NK cells in patients with systemic sclerosis and primary Sjogren's syndrome. Ann Rheum Dis 1994;53:574-9.
19. Southcott AM, Jones KP, Li D, Majumdar S, Cambrey AD, Pantelidis P, et al. Interleukin-8. Differential expression in lone fibrosing alveolitis and systemic sclerosis. Am J Respir Crit Care Med 1995;151:1604-12.
20. Deguchi Y. Spontaneous increase of transforming growth factor beta production by bronchoalveolar mononuclear cells of patients with systemic autoimmune diseases affecting the lung. Ann Rheum Dis 1992;51:362-5.
21. Ludwicka A, Ohba T, Trojanowska M, Yamakage A, Strange C, Smith EA, et al. Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma. J Rheumatol 1995;22:1876-83.
22. Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581-90.
23. LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA, et al. Scleroderma (systemic sclerosis), classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5.
24. Czirják L, Nagy Z, Szegedi G. Systemic sclerosis in the elderly. Clin Rheumatol 1992;11:483-5.
25. Czirják L, Dankó K, Zeher M, Lukács K, Szegedi G. Function of monocytes in patients with systemic sclerosis. Acta Med Hung 1988;45:53-61.
26. Czirják L, Dankó K, Sipka S, Zeher M, Szegedi G. Polymorphonuclear neutrophil function in systemic sclerosis. Ann Rheum Dis 1987;46:302-6.
27. Carroll M, Lukács K, Hodson M, Kay AB. Defective chemotactic factor-induced monocyte complement receptor enhancement in lung cancer. Clin Exp Immunol 1983;54:785-92.
28. Czirják L, Surányi P, Dankó K, Szegedi G. T lymphocyte subpopulations in progressive systemic sclerosis defined by monoclonal antibodies. Acta Med Hung 1985;42:129-32.
29. Czirják L, Dankó K, Zeher M, Szegedi G. Lymphocyte response to mitogens and monocyte-mediated suppression of lymphocyte activation in patients with progressive systemic sclerosis. Ann Immunol Hung 1985;25:167-75.
30. Bolster MB, Ludwicka A, Sutherland SE, Strange C, Silver RM. Cytokine concentrations in bronchoalveolar lavage fluid of patients with systemic sclerosis. Arthritis Rheum 1997;40:743-51.
31. Umehara H, Kumagai S, Murakami M, Suginoshita T, Tanaka K, Hashida S, et al. Enhanced production of interleukin-1 and tumor necrosis factor alpha by cultured peripheral blood monocytes from patients with scleroderma. Arthritis Rheum 1990;33:893-7.
32. Heilig B, Fiehn C, Brockhaus M, Gallati H, Pezzutto A, Hunstein W. Evaluation of soluble tumor necrosis factor (TNF) receptors and TNF receptor antibodies in patients with systemic lupus erythematodes, progressive systemic sclerosis, and mixed connective tissue disease. J Clin Immunol 1993;13:321-8.
33. Hughes P, Holt S, Rowell NR, Allonby ID, Janis K, Dodd JK. The relationship of defective cell-mediated immunity to visceral disease in systemic sclerosis. Clin Exp Immunol 1977;28:233-40.
34. Baron M, Keystone EC, Gladman DD, Lee P, Poplonski L. Lymphocyte subpopulations and reactivity to mitogens in patients with scleroderma. Clin Exp Immunol 1981;46:70-6.
35. Sierakowski S, Bernacka K. Humoral and cellular immunity in progressive systemic sclerosis. Med Interne 1987;25:233-8.
36. Claudy AL, Le Petit JC, Barthelemy H, Garcier F. T-cell imbalance in progressive systemic sclerosis defined by monoclonal antibodies. Arch Dermatol Res 1982;274:189-92.
37. Gustafsson R, Totterman TH, Klareskog L, Hallgren R. Increase in activated T cells and reduction in suppressor inducer T cells in systemic sclerosis. Ann Rheum Dis 1990;49:40-5.
38. Domagala Kulawik J, Hoser G, Kawalec M, Doboszynska A, Kawiak J, Droszcz W. Lymphocyte phenotyping in systemic sclerosis: a flow cytometry analysis of lymphocytes in bronchoalveolar lavage fluid. Anal Quant Cytol Histol 1997;19:264-70.