Microsatellite instability in childhood T cell acute lymphoblastic leukemia

Leukemia

Volumn 11, Issue 6, 1997, Pages 797-802

  Baccichet, A ^a,b   Benachenhou, N ^a,b   Couture, F ^a   Leclerc, J M ^a,c   Sinnett, D ^a,b,c  

^a Ctr de Cancerol Charles Bruneau   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Childhood T cell leukemia; Microsatellite instability; Mismatch repair loci; Mutator phenotype; Relapse

Indexed keywords

MICROSATELLITE DNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER SUSCEPTIBILITY; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME 12P; CHROMOSOME 6P; CHROMOSOME 9P; CLINICAL ARTICLE; DNA REPAIR; DNA REPLICATION; FEMALE; HETEROZYGOSITY LOSS; HUMAN; INFANT; LEUKEMOGENESIS; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTO ONCOGENE; SCHOOL CHILD; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE;

EID: 0030977282     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400650     Document Type: Article

References (14)

1. Champlin R, Gale P. Acute lymphoblastic leukemia: recent advances in biology and therapy. Blood 1989; 73: 2051-2066.
2. Vogelstein B, Kinzler KW. The multistep nature of cancer. Trends Genet 1993; 9: 138-141.
3. Bronner CE, Baker SM, Morisson PT, Warren G, Smith LG, Lescoe MK, Kane M, Earabino C, Lipford J, Lindblom A. Tannergard P, Bollag RJ, Godwin AR, Ward DC, Nordenskjold M, Fishel R, Kolodner R, Liskay M. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994; 368: 258-261.
4. Fishel R, Lescoe MK, Rao MRS, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993; 75: 1027-1038.
5. Leach F, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Peltomäki P, Sistonen P, Aaltonen LA, Nyström-Lahti M, Guan XY, Zhang J, Meltzer PS, Yu JW, Kao FT, Chen DJ, Cerosaletti KM, Fournier REK, Todd S, Lewis T, Leach RJ, Naylor SL, Weissenbach J, Mecklin JP, Järvinen H, Petersen GM, Hamilton SR, Green J, Jass J, Watson P, Lynch HT, Trent JM, de la Chapelle A, Kinzler KW, Vogelstein B. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993; 75: 1215-1225.
6. Nicolaides NC, Papadopoulos N, Liu B, Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Dunlop MG, Hamilton SR, Petersen CM, de la Chapelle A, Vogelstein B, Kinzler KW. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994; 371: 75-80.
7. Papadopoulos N, Nicolaides NC, Wei YF, Ruben SM, Carter KC, Rosen CA, Haseltin WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Hamilton SR, Petersen CM, Watson P, Lynch HT, Peltomäki P, Mecklin JP, de la Chapelle A, Kinzler KW, Vogelstein B. Mutation of a mutL homolog in hereditary colon cancer. Science 1994; 268: 1625-1629.
8. Aaltonen LA, Peltomaki P, Leach FS, Sistonen P, Pylkkanen L, Mecklin JP, Järvinen H, Powell SM, Jen J, Hamilton SR, Petersen GM, Kinzler KW, Vogelstein B, de la Chapelle A. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260: 812-816.
9. lonov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363: 558-561.
10. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260: 816-819.
11. Loeb LA. Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res 1994; 54: 5059-5063.
12. Mao L, Lee DJ, Tockman MS, Erozan YS, Askin F, Sidransky D. Microsatellite alterations as clonal markers for the detection of human cancer. Proc Natl Acad Sci USA 1994; 91: 9871-9875.
13. Krajinovic M, Richer C, Labuda D, Sinnett D. Detection of a mutator phenotype in cancer cells by inter-Alu polymerase chain reaction. Cancer Res 1996; 56: 2733-2737.
14. Cayuela JM, Madani A, Sanhes L, Stern MH, Sigaux F. Multiple tumor-suppressor gene 1 inactivation is the most frequent genetic alteration in T cell acute lymphoblastic leukemia. Blood 1996; 87: 2180-2186.