Maternal viral load and vertical transmission of HIV-1 an important factor but not the only one

AIDS

Volumn 13, Issue 11, 1999, Pages 1377-1385

  Bailey, Andrea ^a   Newell, Marie Louise ^a,f   Peckham, Catherine ^a   De Rossi, Anita ^b   Ehrnst, Anneka ^c   Grosch Wörner, Ilse ^d   Coll, Oriol ^e   De Wolf, Frank ^g  

^a ECS Coordinating Centre   (United Kingdom)

^b UNIVERSITY OF PADOVA   (Italy)

^c KAROLINSKA INSTITUTE   (Sweden)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e HOSPITAL CLÍNIC   (Spain)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g NONE

Author keywords

HIV 1; Mode of delivery; Prematurity; RNA load; Vertical transmission

Indexed keywords

VIRUS RNA;

ADULT; ARTICLE; BLOOD LEVEL; CESAREAN SECTION; CHILD; CONTROLLED STUDY; DELIVERY; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK FACTOR; VAGINAL DELIVERY; VERTICAL TRANSMISSION; VIRUS LOAD;

ADULT; COHORT STUDIES; DELIVERY, OBSTETRIC; DISEASE TRANSMISSION, VERTICAL; EUROPE; FEMALE; GESTATIONAL AGE; HIV INFECTIONS; HIV-1; HUMANS; INFANT; INFANT, NEWBORN; LOGISTIC MODELS; MULTIVARIATE ANALYSIS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PROSPECTIVE STUDIES; RISK FACTORS; RNA, VIRAL; VIRAL LOAD;

EID: 0032867780     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199907300-00016     Document Type: Article

References (33)

1. European Collaborative Study. Vertical transmission of HIV-1: maternal immune status and obstetric factors. AIDS 1996, 10:1675-1681.
2. Gabiano C, Tovo P-A, de Martino M, et al. Mother-to-child transmission of human immunodeficiency virus type 1: risk of infection and correlates of transmission. Pediatr 1992, 90:369-374.
3. Mandelbrot L, Mayaux MJ, Bongain A, et al. Obstetric factors and mother-to-child transmission of human immunodeficiency virus type 1: the French perinatal cohorts. Am J Obstet Gynecol 1996, 175:661-667.
4. De Rossi A, Ometto L, Mammano F, Zanotto C, Giaquinto C, Chieco-Blanchi L. Vertical transmission of HIV-1: lack of detectable virus in peripheral blood cells of infected children at birth. AIDS 1992, 6:1117-1120.
5. Lindgren S, Martin C, Anzen B, Strand H, Bredberg-Raden U, Ehrnst A. Pattern of HIV viraemia and CD4 levels in relation to pregnancy in HIV-1 infected women. Scand J Infect Dis 1996, 28:425-433.
6. Shaffer N, Roongpisuthipong A, Siriwasin W, et al. Maternal viral load and perinatal HIV-1 subtype E transmission, Thailand. J Infect Dis 1998, 179:590-599.
7. Thea DM, Steketee RW, Pliner V, et al. The effect of maternal viral load on the risk of perinatal transmission of HIV-1. AIDS 1997, 11:437-444.
8. Mayaux MJ, Dussaix E, Isopet J, et al. Maternal virus load during pregnancy and mother-to-child transmission of human immunodeficiency virus type 1: the French perinatal cohort studies. J Infect Dis 1997, 175:172-175.
9. Fang G, Burger H, Grimson R, et al. Maternal plasma human immunodefiency virus type 1 RNA level: a determinant and projected threshold for mother-to-child transmission. Proc Natl Acad Sci USA 1995, 92:12100-12104.
10. Dickover RE, Garratty EM, Herman SA, et al. Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission. JAMA 1996, 275:599-605.
11. Sperling RS, Shapiro DE, Coombs RW, et al. Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. N Eng J Med 1996, 335:1621-1629.
12. Cao Y, Krogstad P, Korber BT, et al. Maternal HIV-1 viral load and vertical transmission of infection: the Ariel Project for the prevention of HIV tranmission from mother to infant. Nat Med 1997, 3:549-553.
13. European Collaborative Study. Is zidovudine therapy in pregnant HIV-infected women associated with gestational age and birthweight? AIDS 1999, 13:119-124.
14. The European Mode of Delivery Collaboration. Elective caesarean section versus vaginal delivery in preventing vertical HIV-1 transmission: a randomised clinical trial. Lancet 1999, 353:1035-1039.
15. The International Perinatal HIV group. Mode of delivery and vertical transmission of HIV-1: a meta-analysis from fifteen prospective cohort studies. N Eng J Med 1999, 340:977-987.
16. Revets H, Marissens D, De Wit S, et al. Comparative evaluation of NASBA HIV-1 RNA QT, AMPLICOR-HIV monitor, and QUANTIPLEX HIV RNA assay, three methods for quantification of human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 1996, 34:1058-1064.
17. Schuurman R, Descaps D, Weverling GJ, et al. Multicentre comparison of three commercial methods for quantification of human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 1996, 34:3016-3022.
18. Burns DN, Landesman S, Minkoff H, et al. The influence of pregnancy on human immunodeficiency virus type 1 infection: antepartum and postpartum changes in human immunodeficiency virus type 1 viral load. Am J Obstet Gynecol 1998, 178:355-359.
19. O'Shea S, Newell ML, Dunn D, et al. Maternal viral load, CD4 cell count and vertical transmission of HIV-1. J Med Virol 1998, 54:113-117.
20. Matthews JNS, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. BMJ 1990, 300:230-235.
21. Centers For Disease Control. 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR Morb Mortal Wkly Rep 1994, 43(RR12):1-10.
22. European Collaborative Study. Caesarean section and risk of vertical transmission of HIV-1 infection. Lancet 1994, 343:1464-1467.
23. Connor FM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Eng J Med 1994, 331:1173-1180.
24. European Collaborative Study. Therapeutic and other interventions to reduce the risk of mother-to-child transmission of HIV-1 in Europe. Br J Obstet Gynaecol 1998, 105:704-709.
25. Alaeus A, Leitner I, Lidman K, Albert J. Subtype-specific problems with quantification of plasma HIV-1 RNA. AIDS 1997, 11:859-866.
26. Burns D, Landesman S, Wright DJ, et al. Influence of other maternal variables on the relationship between maternal virus load and mother-to-infant transmission of human immunodeficiency virus type 1. J Infect Dis 1997, 175:1206-1210.
27. Holodniy M, Mole L, Yen-Lieberman B, et al. Comparative stabilities of quantitative human immunodeficiency virus RNA in plasma from samples collected in VACUTAINER CPT, VACUTAINER PPT, and standard VACUTAINER tubes. J Clin Microbiol 1995, 33:1562-1566.
28. Todd J, Pachl C, White RM, et al. Performance characteristics for the quantification of plasma HIV-1 RNA using branched DNA signal amplification technology. J Acquir Immune Defic Syndr Hum Retrovirol 1945, 10(suppl 2):S35-S44.
29. Goudsmit J. Prevention and Clinical Management of AIDS. Amsterdam: Amsterdam University Press; 1996.
30. Ginocchio CC, Wang XP, Kaplan MH, et al. Effects of specimen collection, processing and storage conditions on stability of human immunodeficiency type 1 RNA levels in plasma. J Clin Microbiol 1997, 35:2886-2893.
31. Kuhn L, Steketee RW, Weedon J, et al. Distinct risk factors for intrauterine and intrapartum human immunodeficiency virus transmission and consequences for disease progression in infected children. J Infect Dis 1999, 179:52-58.
32. Iovo P-A, Newell MI, Mandelbrot L, Semprini A, Giaquinto C. Recommendations for the management of HIV infected women and their infants - a European Consensus. European Commission Community Research, Brussels, Belgium. 1999, 1-37.
33. Biggar RJ, Miotti PG, Taha TE, et al. Perinatal intervention trial in Africa: effect of a birth canal cleansing intervention to prevent HIV transmission. Lancet 1996, 347:1647-1650.