-
1
-
-
0030932849
-
Tumor-associated angiogenesis: Mechanisms, clinical implications, and therapeutic strategies
-
J. PLUDA, Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies, Seminars in Oncology 24, 203-218 (1997).
-
(1997)
Seminars in Oncology
, vol.24
, pp. 203-218
-
-
Pluda, J.1
-
2
-
-
0030806436
-
Angiogenesis: New aspects relating to its initiation and control
-
K. NORRBY, Angiogenesis: new aspects relating to its initiation and control, Apmis 105, 417-437 (1997).
-
(1997)
Apmis
, vol.105
, pp. 417-437
-
-
Norrby, K.1
-
3
-
-
0030920373
-
Markers of tumor angiogenesis: Clinical applications in prognosis and anti-angiogenic therapy
-
S. B. FOX and A. L. HARRIS, Markers of tumor angiogenesis: clinical applications in prognosis and anti-angiogenic therapy, Investigational New Drugs 15, 15-28 (1997).
-
(1997)
Investigational New Drugs
, vol.15
, pp. 15-28
-
-
Fox, S.B.1
Harris, A.L.2
-
4
-
-
0030059451
-
What, if anything, is an angiogenic factor?
-
W. RISAU, What, if anything, is an angiogenic factor?, Cancer and Metastasis Reviews 15, 149-151 (1996).
-
(1996)
Cancer and Metastasis Reviews
, vol.15
, pp. 149-151
-
-
Risau, W.1
-
6
-
-
0030758704
-
Angiogenesis: A dynamic balance of stimulators and inhibitors
-
M. L. IRUELA-ARISPE and H. F. DVORAK, Angiogenesis: a dynamic balance of stimulators and inhibitors, Thrombosis and Haemostasis 78, 672-677 (1997).
-
(1997)
Thrombosis and Haemostasis
, vol.78
, pp. 672-677
-
-
Iruela-Arispe, M.L.1
Dvorak, H.F.2
-
7
-
-
0031011882
-
Angiogenic factors as tumor markers
-
M. NGUYEN, Angiogenic factors as tumor markers, Investigational New Drugs 15, 29-37 (1997).
-
(1997)
Investigational New Drugs
, vol.15
, pp. 29-37
-
-
Nguyen, M.1
-
8
-
-
0030498430
-
Clinical significance of the determination of angiogenic factors
-
M. TOI, T. TANIGUCHI, Y. YAMAMOTO, T. KURISAKI, H. SUZUKI and T. TOMINAGA, Clinical significance of the determination of angiogenic factors, European Journal of Cancer 32A, 2513-2519 (1996).
-
(1996)
European Journal of Cancer
, vol.32 A
, pp. 2513-2519
-
-
Toi, M.1
Taniguchi, T.2
Yamamoto, Y.3
Kurisaki, T.4
Suzuki, H.5
Tominaga, T.6
-
9
-
-
0029790295
-
Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma
-
Y. TAKEBAYASHI, S. AKIYAMA, S. AKIBA, K. YAMADA, K. MIYADERA, T. SUMIZAWA, Y. YAMADA, F. MURATA and T. AIKOU, Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma, J. Natl. Cancer Inst. 88, 1110-1117 (1996).
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 1110-1117
-
-
Takebayashi, Y.1
Akiyama, S.2
Akiba, S.3
Yamada, K.4
Miyadera, K.5
Sumizawa, T.6
Yamada, Y.7
Murata, F.8
Aikou, T.9
-
10
-
-
0001340091
-
The activity and expression of thymidine phosphorylase in human solid tumours
-
Y. TAKEBAYASHI, K. YAMADA, K. MIYADERA, T. SUMIZAWA, T. FURUKAWA, F. KINOSHITA, D. AOKI, H. OKUMURA, Y. YAMADA, S. AKIYAMA and T. AIKOU, The activity and expression of thymidine phosphorylase in human solid tumours, European J. Cancer 32A, 1227-1232 (1996).
-
(1996)
European J. Cancer
, vol.32 A
, pp. 1227-1232
-
-
Takebayashi, Y.1
Yamada, K.2
Miyadera, K.3
Sumizawa, T.4
Furukawa, T.5
Kinoshita, F.6
Aoki, D.7
Okumura, H.8
Yamada, Y.9
Akiyama, S.10
Aikou, T.11
-
11
-
-
0029821907
-
Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers
-
T. S. O'BRIEN, S. B. FOX, A. J. DICKINSON, H. TURLEY, M. WESTWOOD, A. MOGHADDAM, K. C. GATTER, R. BICKNELL and A. L. HARRIS, Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers, Cancer Research 56, 4799-4804 (1996).
-
(1996)
Cancer Research
, vol.56
, pp. 4799-4804
-
-
O'Brien, T.S.1
Fox, S.B.2
Dickinson, A.J.3
Turley, H.4
Westwood, M.5
Moghaddam, A.6
Gatter, K.C.7
Bicknell, R.8
Harris, A.L.9
-
12
-
-
0030027519
-
The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium
-
S. B. FOX, M. WESTWOOD, A. MOGHADDAM, M. COMLEY, H. TURLEY, R. M. WHITEHOUSE, R. BICKNELL, K. C. GATTER and A. L. HARRIS, The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium, British J. Cancer 73, 275-280 (1996).
-
(1996)
British J. Cancer
, vol.73
, pp. 275-280
-
-
Fox, S.B.1
Westwood, M.2
Moghaddam, A.3
Comley, M.4
Turley, H.5
Whitehouse, R.M.6
Bicknell, R.7
Gatter, K.C.8
Harris, A.L.9
-
13
-
-
0031058350
-
The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo
-
L. GRIFFITHS, G. U. DACHS, R. BICKNELL, A. L. HARRIS and I. J. STRATFORD, The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo, Cancer Res. 57, 570-572 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 570-572
-
-
Griffiths, L.1
Dachs, G.U.2
Bicknell, R.3
Harris, A.L.4
Stratford, I.J.5
-
14
-
-
0030823968
-
Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells
-
H. YOSHIJI, S. R. HARRIS and U. P. THORGEIRSSON, Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells, Cancer Res. 57, 3924-3928 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 3924-3928
-
-
Yoshiji, H.1
Harris, S.R.2
Thorgeirsson, U.P.3
-
15
-
-
0030908042
-
Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells
-
H. ABEDI and I. ZACHARY, Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells, J. Biol. Chem. 272, 15442-15451 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15442-15451
-
-
Abedi, H.1
Zachary, I.2
-
16
-
-
0030323007
-
A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth
-
B. ANAND-APTE, L. BAO, R. SMITH, K. IWATA, B. R. OLSEN, B. ZETTER and S. S. APTE, A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth, Biochemistry and Cell Biology 74, 853-862 (1996).
-
(1996)
Biochemistry and Cell Biology
, vol.74
, pp. 853-862
-
-
Anand-Apte, B.1
Bao, L.2
Smith, R.3
Iwata, K.4
Olsen, B.R.5
Zetter, B.6
Apte, S.S.7
-
17
-
-
0030884164
-
Effect of host microenvironment on the microcirculation of human colon adenocarcinoma
-
D. FUKUMURA, F. YUAN, W. L. MONSKY, Y. CHEN and R. K. JAIN, Effect of host microenvironment on the microcirculation of human colon adenocarcinoma, Am. J. Pathology 151, 679-688 (1997).
-
(1997)
Am. J. Pathology
, vol.151
, pp. 679-688
-
-
Fukumura, D.1
Yuan, F.2
Monsky, W.L.3
Chen, Y.4
Jain, R.K.5
-
18
-
-
0031090132
-
Geometric resistance and microvascular network architecture of human colorectal carcinoma
-
J. R. LESS, M. C. POSNER, T. C. SKALAK, N. WOLMARK and R. K. JAIN, Geometric resistance and microvascular network architecture of human colorectal carcinoma, Microcirculation 4, 25-33 (1997).
-
(1997)
Microcirculation
, vol.4
, pp. 25-33
-
-
Less, J.R.1
Posner, M.C.2
Skalak, T.C.3
Wolmark, N.4
Jain, R.K.5
-
19
-
-
0031089415
-
Landis Award Lecture 1996. Delivery of molecular and cellular medicine to solid tumors
-
R. K. JAIN and M. THE EUGENE, Landis Award Lecture 1996. Delivery of molecular and cellular medicine to solid tumors, Microcirculation 4, 1-23 (1997).
-
(1997)
Microcirculation
, vol.4
, pp. 1-23
-
-
Jain, R.K.1
The Eugene, M.2
-
20
-
-
0030018743
-
A systems approach to cancer therapy. (Antioncogenics + standard cytotoxics → mechanism(s) of interaction)
-
B. A. TEICHER, A systems approach to cancer therapy. (Antioncogenics + standard cytotoxics → mechanism(s) of interaction), Cancer and Metastasis Reviews 15, 247-272 (1996).
-
(1996)
Cancer and Metastasis Reviews
, vol.15
, pp. 247-272
-
-
Teicher, B.A.1
-
21
-
-
0030806273
-
Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
-
L. E. BENJAMIN and E. KESHET, Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal, Proc. Natl. Acad. Sciences, U.S.A. 94, 8761-8766 (1997).
-
(1997)
Proc. Natl. Acad. Sciences, U.S.A.
, vol.94
, pp. 8761-8766
-
-
Benjamin, L.E.1
Keshet, E.2
-
22
-
-
0030641090
-
Vascular permeability factor/vascular endothelial growth factor: A multifunctional angiogenic cytokine
-
L. F. BROWN, M. DETMAR, K. CLAFFEY, J. A. NAGY, D. FENG, A. M. DVORAK and H. F. DVORAK, Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine, Exs 79, 233-269 (1997).
-
(1997)
Exs
, vol.79
, pp. 233-269
-
-
Brown, L.F.1
Detmar, M.2
Claffey, K.3
Nagy, J.A.4
Feng, D.5
Dvorak, A.M.6
Dvorak, H.F.7
-
23
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
R. J. D'AMATO, M. S. LOUGHNAN, E. FLYNN and J. FOLKMAN, Thalidomide is an inhibitor of angiogenesis, Proc. Natl. Acad. Sciences, U.S.A. 91, 4082-4085 (1994).
-
(1994)
Proc. Natl. Acad. Sciences, U.S.A.
, vol.91
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
24
-
-
0029143990
-
Tumor angiogenesis in breast cancer: Its importance as a prognostic indicator and the association with vascular endothelial growth factor expression
-
M. TOI, K. INADA, H. SUZUKI and T. TOMINAGA, Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression, Breast Cancer Research and Treatment 36, 193-204 (1995).
-
(1995)
Breast Cancer Research and Treatment
, vol.36
, pp. 193-204
-
-
Toi, M.1
Inada, K.2
Suzuki, H.3
Tominaga, T.4
-
25
-
-
0028085449
-
Molecular mechanisms of developmental and tumor angiogenesis
-
K. H. PLATE, G. BREIER and W. RISAU, Molecular mechanisms of developmental and tumor angiogenesis, Brain Pathology 4, 207-218 (1994).
-
(1994)
Brain Pathology
, vol.4
, pp. 207-218
-
-
Plate, K.H.1
Breier, G.2
Risau, W.3
-
26
-
-
0029128360
-
Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer
-
M. TOI, K. INADA, S. HOSHINA, H. SUZUKI, S. KONDO and T. TOMINAGA, Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer, Clinical Cancer Res. 1, 961-964 (1995).
-
(1995)
Clinical Cancer Res.
, vol.1
, pp. 961-964
-
-
Toi, M.1
Inada, K.2
Hoshina, S.3
Suzuki, H.4
Kondo, S.5
Tominaga, T.6
-
27
-
-
0029155712
-
Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia
-
A. J. GUIDI, G. ABU-JAWDEH, B. BERSE, R. W. JACKMAN, K. TOGNAZZI, H. F. DVORAK and L. F. BROWN, Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia, J. Natl. Cancer Inst. 87, 1237-1245 (1995).
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 1237-1245
-
-
Guidi, A.J.1
Abu-Jawdeh, G.2
Berse, B.3
Jackman, R.W.4
Tognazzi, K.5
Dvorak, H.F.6
Brown, L.F.7
-
28
-
-
0028906219
-
Vascular endothelial growth factor expression and angiogenesis in non-small cell lung carcinomas
-
J. MATTERN, R. KOOMAGI and M. VOLM, Vascular endothelial growth factor expression and angiogenesis in non-small cell lung carcinomas, Intl. Oncology 6, 1059-1062 (1995).
-
(1995)
Intl. Oncology
, vol.6
, pp. 1059-1062
-
-
Mattern, J.1
Koomagi, R.2
Volm, M.3
-
29
-
-
0030066037
-
Prognostic value of vascular endothelial growth factor expression in gastric carcinoma
-
K. MAEDA, Y. S. CHUNG, Y. OGAWA, S. TAKATSUKA, S. M. KANG, M. OGAWA, T. SAWADA and M. SOWA, Prognostic value of vascular endothelial growth factor expression in gastric carcinoma, Cancer 77, 858-863 (1996).
-
(1996)
Cancer
, vol.77
, pp. 858-863
-
-
Maeda, K.1
Chung, Y.S.2
Ogawa, Y.3
Takatsuka, S.4
Kang, S.M.5
Ogawa, M.6
Sawada, T.7
Sowa, M.8
-
30
-
-
84970070220
-
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis and proliferation of human colon cancer
-
Y. TAKAHASHI, Y. KITADAI, C. D. BUCANA, K. R. CLEARY and L. M. ELLIS, Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis and proliferation of human colon cancer, Cancer Res. 55, 3964-3968 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 3964-3968
-
-
Takahashi, Y.1
Kitadai, Y.2
Bucana, C.D.3
Cleary, K.R.4
Ellis, L.M.5
-
31
-
-
0030821453
-
Vascular endothelial growth factor (VEGF) in human breast cancer: Correlation with disease-free survival
-
A. OBERMAIR, E. KUCERA, K. MAYERHOFER, P. SPEISER, M. SEIFERT, K. CZERWENKA, A. KAIDER, S. LEODOLTER, C. KAINZ and R. ZEILLINGER, Vascular endothelial growth factor (VEGF) in human breast cancer: correlation with disease-free survival, Intl. J. Cancer 74, 455-458 (1997).
-
(1997)
Intl. J. Cancer
, vol.74
, pp. 455-458
-
-
Obermair, A.1
Kucera, E.2
Mayerhofer, K.3
Speiser, P.4
Seifert, M.5
Czerwenka, K.6
Kaider, A.7
Leodolter, S.8
Kainz, C.9
Zeillinger, R.10
-
32
-
-
0028861231
-
Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer
-
L. F. BROWN, B. BERSE, R. W. JACKMAN, K. TOGNAZZI, A. J. GUIDI, H. F. DVORAK, D. R. SENGER, J. L. CONNOLLY and S. J. SCHNITT, Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer, Human Pathology 26, 86-91 (1995).
-
(1995)
Human Pathology
, vol.26
, pp. 86-91
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
Tognazzi, K.4
Guidi, A.J.5
Dvorak, H.F.6
Senger, D.R.7
Connolly, J.L.8
Schnitt, S.J.9
-
33
-
-
0028904030
-
Expression of vascular endothelial growth factor and its receptors fit and KDR in ovarian carcinoma
-
C. A. BOOCOCK, D. S. CHARNOCK-JONES, A. M. SHARKEY, J. MCLAREN, P. J. BARKER, K. A. WRIGHT, P. R. TWENTYMAN and S. K. SMITH, Expression of vascular endothelial growth factor and its receptors fit and KDR in ovarian carcinoma, J. Natl. Cancer Inst. 87, 506-516 (1995).
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 506-516
-
-
Boocock, C.A.1
Charnock-Jones, D.S.2
Sharkey, A.M.3
Mclaren, J.4
Barker, P.J.5
Wright, K.A.6
Twentyman, P.R.7
Smith, S.K.8
-
34
-
-
0027432324
-
Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
-
K. H. PLATE, G. BREIER, B. MILLAUER, A. ULLRICH and W. RISAU, Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis, Cancer Res. 53, 5822-5827 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 5822-5827
-
-
Plate, K.H.1
Breier, G.2
Millauer, B.3
Ullrich, A.4
Risau, W.5
-
35
-
-
0027768808
-
Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas
-
L. F. BROWN, B. BERSE, R. W. JACKMAN, K. TOGNAZZI, E. J. MANSEAU, H. F. DVORAK and D. R. SENGER, Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas, Am. J. Pathology 143, 1255-1262 (1993).
-
(1993)
Am. J. Pathology
, vol.143
, pp. 1255-1262
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
Tognazzi, K.4
Manseau, E.J.5
Dvorak, H.F.6
Senger, D.R.7
-
36
-
-
2642709170
-
Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth
-
P. XIA, L. P. AIELLO, H. ISHII, Z. Y. JIANG, D. J. PARK, G. S. ROBINSON, H. TAKAGI, W. P. NEWSOME, M. R. JIROUSEK and G. L. KING, Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth, J. Clinical Investigation 98, 2018-2026 (1996).
-
(1996)
J. Clinical Investigation
, vol.98
, pp. 2018-2026
-
-
Xia, P.1
Aiello, L.P.2
Ishii, H.3
Jiang, Z.Y.4
Park, D.J.5
Robinson, G.S.6
Takagi, H.7
Newsome, W.P.8
Jirousek, M.R.9
King, G.L.10
-
37
-
-
0028899424
-
Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation
-
D. GUO, Q. JIA, H. Y. SONG, R. S. WARREN and D. B. DONNER, Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation, J. Biol. Chem. 270, 6729-6733 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6729-6733
-
-
Guo, D.1
Jia, Q.2
Song, H.Y.3
Warren, R.S.4
Donner, D.B.5
-
38
-
-
0031577563
-
The phosphorylated 1169-tyrosine containing region of fit-1 kinase (VEGFR-1) is a major binding site for PLCgamma
-
A. SAWANO, T. TAKAHASHI, S. YAMAGUCHI and M. SHIBUYA, The phosphorylated 1169-tyrosine containing region of fit-1 kinase (VEGFR-1) is a major binding site for PLCgamma, Biochem. Biophys. Res. Commun. 238, 487-491 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 487-491
-
-
Sawano, A.1
Takahashi, T.2
Yamaguchi, S.3
Shibuya, M.4
-
39
-
-
0030027488
-
Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction
-
M. MOHAMMADI, I. DIKIC, A. SOROKIN, W. H. BURGESS, M. JAYE and J. SCHLESSINGER, Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction, Molecular and Cellular Biology 16, 977-989 (1996).
-
(1996)
Molecular and Cellular Biology
, vol.16
, pp. 977-989
-
-
Mohammadi, M.1
Dikic, I.2
Sorokin, A.3
Burgess, W.H.4
Jaye, M.5
Schlessinger, J.6
-
40
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Y. NISHIZUKA, Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C, Science 258, 607-614 (1992).
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
41
-
-
8944246315
-
(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase C beta
-
M. R. JIROUSEK, J. R. GILLIG, C. M. GONZALEZ, W. F. HEATH, J. H. MCDONALD, D. A. NEEL, C. J. RITO, U. SINGH, L. E. STRAMM, A. MELIKIAN-BADALIAN, M. BAEVSKY, L. M. BALLAS, S. E. HALL, L. L. WINNEROSKI and M. M. FAUL, (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta, J. Medicinal Chem. 39, 2664-2671 (1996).
-
(1996)
J. Medicinal Chem.
, vol.39
, pp. 2664-2671
-
-
Jirousek, M.R.1
Gillig, J.R.2
Gonzalez, C.M.3
Heath, W.F.4
Mcdonald, J.H.5
Neel, D.A.6
Rito, C.J.7
Singh, U.8
Stramm, L.E.9
Melikian-Badalian, A.10
Baevsky, M.11
Ballas, L.M.12
Hall, S.E.13
Winneroski, L.L.14
Faul, M.M.15
-
42
-
-
0031964664
-
Inhibition of intraocular neovascularization caused by retinal ischemia in pigs by PKCbeta inhibition with LY333531
-
R. P. DANIS, D. P. BINGAMAN, M. JIROUSEK and Y. YANG, Inhibition of intraocular neovascularization caused by retinal ischemia in pigs by PKCbeta inhibition with LY333531, Investigative Ophthalmology and Visual Science 39, 171-179 (1998).
-
(1998)
Investigative Ophthalmology and Visual Science
, vol.39
, pp. 171-179
-
-
Danis, R.P.1
Bingaman, D.P.2
Jirousek, M.3
Yang, Y.4
-
43
-
-
15644366961
-
Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor
-
L. P. AIELLO, S. E. BURSELL, A. CLERMONT, E. DUH, H. ISHII, C. TAKAGI, F. MORI, T. A. CIULLA, K. WAYS, M. JIROUSEK, L. E. SMITH and G. L. KING, Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor, Diabetes 46, 1473-1480 (1997).
-
(1997)
Diabetes
, vol.46
, pp. 1473-1480
-
-
Aiello, L.P.1
Bursell, S.E.2
Clermont, A.3
Duh, E.4
Ishii, H.5
Takagi, C.6
Mori, F.7
Ciulla, T.A.8
Ways, K.9
Jirousek, M.10
Smith, L.E.11
King, G.L.12
-
44
-
-
13344293711
-
Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor
-
H. ISHII, M. R. JIROUSEK, D. KOYA, C. TAKAGI, P. XIA, A. CLERMONT, S. E. BURSELL, T. S. KERN, L. M. BALLAS, W. F. HEATH, L. E. STRAMM, E. P. FEENER and G. L. KING, Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor, Science 272, 728-731 (1996).
-
(1996)
Science
, vol.272
, pp. 728-731
-
-
Ishii, H.1
Jirousek, M.R.2
Koya, D.3
Takagi, C.4
Xia, P.5
Clermont, A.6
Bursell, S.E.7
Kern, T.S.8
Ballas, L.M.9
Heath, W.F.10
Stramm, L.E.11
Feener, E.P.12
King, G.L.13
-
45
-
-
0028305809
-
Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents
-
B. A. TEICHER, S. A. HOLDEN, G. ARA, E. ALVAREZ, Z. D. HUANG, Y. N. CHEN and H. BREM, Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents, Intl. J. Cancer 57, 920-925 (1994).
-
(1994)
Intl. J. Cancer
, vol.57
, pp. 920-925
-
-
Teicher, B.A.1
Holden, S.A.2
Ara, G.3
Alvarez, E.4
Huang, Z.D.5
Chen, Y.N.6
Brem, H.7
-
46
-
-
0030920374
-
Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents
-
Y. KAKEJI and B. A. TEICHER, Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents, Investigational New Drugs 15, 39-48 (1997).
-
(1997)
Investigational New Drugs
, vol.15
, pp. 39-48
-
-
Kakeji, Y.1
Teicher, B.A.2
-
47
-
-
0017412603
-
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice
-
J. FOGH, J. M. FOGH and T. ORFEO, One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice, J. Natl. Cancer Inst. 59, 221-226 (1977).
-
(1977)
J. Natl. Cancer Inst.
, vol.59
, pp. 221-226
-
-
Fogh, J.1
Fogh, J.M.2
Orfeo, T.3
-
48
-
-
0026486664
-
Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease
-
B. TEICHER, A. ES and Z. HUANG, Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease, Cancer Res. 52, 6702-6704 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6702-6704
-
-
Teicher, B.1
Es, A.2
Huang, Z.3
-
49
-
-
0027143743
-
Beta-cyclodextrin tetradecasulfate/tetrahydrocortisol ± minocycline as modulators of cancer therapies in vitro and in vivo against primary and metastatic Lewis lung carcinoma
-
B. TEICHER, S. HOLDEN, G. ARA, E. ALVAREZ, Z. HUANG, Y. CHEN and V. KHANDEKAR, Beta-cyclodextrin tetradecasulfate/tetrahydrocortisol ± minocycline as modulators of cancer therapies in vitro and in vivo against primary and metastatic Lewis lung carcinoma, Cancer Chemotherapy and Pharmacology 33, 229-238 (1993).
-
(1993)
Cancer Chemotherapy and Pharmacology
, vol.33
, pp. 229-238
-
-
Teicher, B.1
Holden, S.2
Ara, G.3
Alvarez, E.4
Huang, Z.5
Chen, Y.6
Khandekar, V.7
-
50
-
-
0029971486
-
Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma
-
B. A. TEICHER, S. A. HOLDEN, G. ARA, T. KORBUT and K. MENON, Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma, Cancer Chemotherapy and Pharmacology 38, 169-177 (1996).
-
(1996)
Cancer Chemotherapy and Pharmacology
, vol.38
, pp. 169-177
-
-
Teicher, B.A.1
Holden, S.A.2
Ara, G.3
Korbut, T.4
Menon, K.5
-
51
-
-
0029069833
-
Influence of an anti-angiogenic treatment on 9L gliosarcoma: Oxygenation and response to cytotoxic therapy
-
B. A. TEICHER, S. A. HOLDEN, G. ARA, N. P. DUPUIS, F. LIU, J. YUAN, M. IKEBE and Y. KAKEJI, Influence of an anti-angiogenic treatment on 9L gliosarcoma: oxygenation and response to cytotoxic therapy, Intl. J. Cancer 61, 732-737 (1995).
-
(1995)
Intl. J. Cancer
, vol.61
, pp. 732-737
-
-
Teicher, B.A.1
Holden, S.A.2
Ara, G.3
Dupuis, N.P.4
Liu, F.5
Yuan, J.6
Ikebe, M.7
Kakeji, Y.8
-
52
-
-
0022964712
-
The characteristic structural features of the blood vessels of the Lewis lung carcinoma (a light microscopic and scanning electron microscopic study)
-
T. W. GRUNT, A. LAMETSCHWANDTNER and K. KARRER, The characteristic structural features of the blood vessels of the Lewis lung carcinoma (a light microscopic and scanning electron microscopic study). Scanning Electron Microscopy 575-589 (1986).
-
(1986)
Scanning Electron Microscopy
, pp. 575-589
-
-
Grunt, T.W.1
Lametschwandtner, A.2
Karrer, K.3
-
53
-
-
0022962804
-
The angioarchitecture of the Lewis lung carcinoma in laboratory mice (a light microscopic and scanning electron microscopic study)
-
T. W. GRUNT, A. LAMETSCHWANDTNER, K. KARRER and O. STAINDL, The angioarchitecture of the Lewis lung carcinoma in laboratory mice (a light microscopic and scanning electron microscopic study). Scanning Electron Microscopy 557-573 (1986).
-
(1986)
Scanning Electron Microscopy
, pp. 557-573
-
-
Grunt, T.W.1
Lametschwandtner, A.2
Karrer, K.3
Staindl, O.4
-
54
-
-
0026605205
-
cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: Potential involvement of a protein kinase C-dependent signaling pathway
-
E. RUBIN, S. KHARBANDA, H. GUNJI, R. WEICHSELBAUM and D. KUFE, cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway, Cancer Res. 52, 878-882 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 878-882
-
-
Rubin, E.1
Kharbanda, S.2
Gunji, H.3
Weichselbaum, R.4
Kufe, D.5
-
55
-
-
0025867205
-
Regulation of c-jun gene expression in HL-60 leukemia cells by 1-beta-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism
-
S. KHARBANDA, R. DATTA and D. KUFE, Regulation of c-jun gene expression in HL-60 leukemia cells by 1-beta-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism, Biochemistry 30, 7947-7952 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 7947-7952
-
-
Kharbanda, S.1
Datta, R.2
Kufe, D.3
-
56
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
A. HAIMOVITZ-FRIEDMAN, C. C. KAN, D. EHLEITER, R. S. PERSAUD, M. MCLOUGHLIN, Z. FUKS and R. N. KOLESNICK, Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis, J. Exptl. Medicine 180, 525-535 (1994).
-
(1994)
J. Exptl. Medicine
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Kan, C.C.2
Ehleiter, D.3
Persaud, R.S.4
Mcloughlin, M.5
Fuks, Z.6
Kolesnick, R.N.7
-
57
-
-
0026005817
-
Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation
-
D. E. HALLAHAN, S. VIRUDACHALAM, M. L. SHERMAN, E. HUBERMAN, D. W. KUFE and R. R. WEICHSELBAUM, Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation, Cancer Res. 51, 4565-4569 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 4565-4569
-
-
Hallahan, D.E.1
Virudachalam, S.2
Sherman, M.L.3
Huberman, E.4
Kufe, D.W.5
Weichselbaum, R.R.6
-
58
-
-
0030064582
-
Induction and phosphorylation of protein kinase C-alpha and mitogen-activated protein kinase by hypoxia and by radiation in Chinese hamster V79 cells
-
N. M. HASAN, P. J. PARKER and G. E. ADAMS, Induction and phosphorylation of protein kinase C-alpha and mitogen-activated protein kinase by hypoxia and by radiation in Chinese hamster V79 cells, Radiation Res. 145, 128-133 (1996).
-
(1996)
Radiation Res.
, vol.145
, pp. 128-133
-
-
Hasan, N.M.1
Parker, P.J.2
Adams, G.E.3
-
59
-
-
0027322773
-
Inhibition of phorbol ester-induced T cell proliferation by bryostatin is associated with rapid degradation of protein kinase C
-
N. ISAKOV, D. GALRON, T. MUSTELIN, G. R. PETTIT and A. ALTMAN, Inhibition of phorbol ester-induced T cell proliferation by bryostatin is associated with rapid degradation of protein kinase C, J. Immunology 150, 1195-1204 (1993).
-
(1993)
J. Immunology
, vol.150
, pp. 1195-1204
-
-
Isakov, N.1
Galron, D.2
Mustelin, T.3
Pettit, G.R.4
Altman, A.5
-
60
-
-
0028126624
-
Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation
-
Z. SZALLASI, M. F. DENNING, C. B. SMITH, A. A. DLUGOSZ, S. H. YUSPA, G. R. PETTIT and P. M. BLUMBERG, Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation, Molecular Pharmacology 46, 840-850 (1994).
-
(1994)
Molecular Pharmacology
, vol.46
, pp. 840-850
-
-
Szallasi, Z.1
Denning, M.F.2
Smith, C.B.3
Dlugosz, A.A.4
Yuspa, S.H.5
Pettit, G.R.6
Blumberg, P.M.7
-
61
-
-
0028055160
-
Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts
-
Z. SZALLASI, C. B. SMITH, G. R. PETTIT and P. M. BLUMBERG, Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts, J. Biol. Chem. 269, 2118-2124 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2118-2124
-
-
Szallasi, Z.1
Smith, C.B.2
Pettit, G.R.3
Blumberg, P.M.4
-
62
-
-
0026481364
-
Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: Association with enhanced fragmentation of mature DNA
-
S. GRANT, W. D. JARVIS, P. S. SWERDLOW, A. J. TURNER, R. S. TRAYLOR, H. J. WALLACE, P. S. LIN, G. R. PETTIT and D. A. GEWIRTZ, Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA, Cancer Res. 52, 6270-6278 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6270-6278
-
-
Grant, S.1
Jarvis, W.D.2
Swerdlow, P.S.3
Turner, A.J.4
Traylor, R.S.5
Wallace, H.J.6
Lin, P.S.7
Pettit, G.R.8
Gewirtz, D.A.9
-
63
-
-
0028181584
-
Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells
-
W. D. JARVIS, L. F. POVIRK, A. J. TURNER, R. S. TRAYLOR, D. A. GEWIRTZ, G. R. PETTIT and S. GRANT, Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells, Biochem. Pharmacol. 47, 839-852 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 839-852
-
-
Jarvis, W.D.1
Povirk, L.F.2
Turner, A.J.3
Traylor, R.S.4
Gewirtz, D.A.5
Pettit, G.R.6
Grant, S.7
-
64
-
-
0024402595
-
Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C
-
D. J. MCCONKEY, P. HARTZELL, M. JONDAL and S. ORRENIUS, Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C, J. Biol. Chem. 264, 13399-13402 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13399-13402
-
-
Mcconkey, D.J.1
Hartzell, P.2
Jondal, M.3
Orrenius, S.4
-
65
-
-
0023750235
-
Inhibition of radiation-induced apoptosis in vitro by tumor promoters
-
L. D. TOMEI, P. KANTER and C. E. WENNER, Inhibition of radiation-induced apoptosis in vitro by tumor promoters, Biochem. Biophys. Res. Commun. 155, 324-331 (1988).
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.155
, pp. 324-331
-
-
Tomei, L.D.1
Kanter, P.2
Wenner, C.E.3
-
66
-
-
0029610677
-
Definition of two angiogenic pathways by distinct alpha v integrins
-
M. FRIEDLANDER, P. C. BROOKS, R. W. SHAFFER, C. M. KINCAID, J. A. VARNER and D. A. CHERESH, Definition of two angiogenic pathways by distinct alpha v integrins, Science 270, 1500-1502 (1995).
-
(1995)
Science
, vol.270
, pp. 1500-1502
-
-
Friedlander, M.1
Brooks, P.C.2
Shaffer, R.W.3
Kincaid, C.M.4
Varner, J.A.5
Cheresh, D.A.6
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