Transcriptional induction of p69 2'-5'-oligoadenylate synthetase by interferon-α is stimulated by 12-O-tetradecanoyl phorbol-13-acetate through IRF/ISRE binding motifs

Gene

Volumn 237, Issue 1, 1999, Pages 177-184

  Yu, Fang ^a   Wang, Qing ^a   Floyd Smith, Georgia ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Antiviral; Interferon; ISGF3; ISRE; Protein kinase C; TPA

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ALPHA INTERFERON; INTERFERON REGULATORY FACTOR 1; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DAUDI CELL; DELETION MUTANT; ENZYME ACTIVITY; GENE CONSTRUCT; GENE INDUCTION; IN VITRO STUDY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION;

2',5'-OLIGOADENYLATE SYNTHETASE; AMINO ACID MOTIFS; BINDING SITES; CELL EXTRACTS; DNA-BINDING PROTEINS; HUMANS; INTERFERON REGULATORY FACTORS; INTERFERON-ALPHA; INTERFERON-STIMULATED GENE FACTOR 3; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; POINT MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; RECOMBINANT PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; RESPONSE ELEMENTS; STAT1 TRANSCRIPTION FACTOR; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0032865438     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00284-X     Document Type: Article

References (25)

1. Cao X., Tay A., Guy G.R., Tan Y.H. Activation and association of Stat3 with Src in v-Src-transformed cell lines. Mol. Cell. Biol. 16:1996;1595-1603.
2. Chang C.C., Borelli T.J., Williams B.R., Wu J.M. Transcriptional activation of human (2′-5′)oligoadenylate synthetase gene expression by the phorbol ester 12-O-tetradecanoyl-phorbol 13-acetate in type-I-interferon-treated HL-60 and HeLa cells. Eur. J. Biochem. 207:1992;297-304.
3. Chebath J., Benech P., Hovanessian A.G., Galabru J., Revel M. Four different forms of interferon-induced 2′-5′-oligo(A) synthetase identified by immunoblotting in human cells. J. Biol. Chem. 262:1987;3852-3857.
4. Darnell J.E., Kerr I.M., Stark G.R. Jak-STAT Pathways to IFNs and other signaling proteins. Science. 264:1994;1415-1421.
5. Eilers A., Georgellis D., Klose B., Schindler C., Ziemiecki A., Harpur A.G., Wilks A.F., Decker T. Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages. Mol. Cell. Biol. 15:1995;3579-3586.
6. Floyd-Smith G., Wang Q., Sen G.C. Transcriptional induction of the p69 isoform of 2′-5′-oligoadenylate synthetase by interferon-β and interferon-γ involves three regulatory elements and interferon-stimulated gene factor 3. Exp. Cell Res. 246:1999;138-147.
7. Garcia-Blanco M.A., Lengyel P., Morrison E., Brownlee C., Stiles C.D., Rutherford M., Hannigan G., Williams B.R. Regulation of 2′,5′-oligoadenylate synthetase gene expression by interferons and platelet-derived growth factor. Mol. Cell. Biol. 9:1989;1060-1068.
8. Hovanessian A.G., Svab J., Marié I., Robert W., Chamaret S., Laurent A.G. Characterization of 69- and 100 kDa forms of 2-5A-synthetase from interferon treated human cells. J. Biol. Chem. 263:1988;4945-4949.
9. Improta T., Schindler C., Horvath C.M., Kerr I.M., Stark G.R., Darnell J.E. Jr. ISGF-3 formation requires phosphoylated Stat91 but Stat 113 is phosphorylated independently of Stat 91. Proc. Natl. Acad. Sci. USA. 91:1994;4776-4780.
10. Kerr I.M., Brown R.E. pppA2′p5′A2′p5′A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells. Proc. Natl. Acad. Sci. USA. 75:1978;256-260.
11. Kessler D.S., Levy D.E. Protein kinase activity required for an early step in interferon-alpha signaling. J. Biol. Chem. 266:1991;23471-23476.
12. Kumar R., Korutla L., Zhang K. Cell cycle-dependent modulation of α-interferon-inducible gene expression and activation of signaling components in Daudi cells. J. Biol. Chem. 269:1994;25437-25441.
13. Marié I., Svab J., Robert N., Galabru J., Hovanessian A.G. Differential expression and distinct structure of 69- and 100-kDa forms of 2-5A synthetase in human cells treated with interferon. J. Biol. Chem. 265:1990;18601-18607.
14. Nguyen H., Hiscott J., Pitha P.M. The growing family of interferon regulatory factors. Cytokine Growth Factor Rev. 8:1997;293-312.
15. Pellegrini S., Dusanter-Fourt I. The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs). Eur. J. Biochem. 248:1997;615-633.
16. Reich N.C., Pfeffer L.M. Evidence for involvement of protein kinase C in the cellular response to interferon alpha. Proc. Natl. Acad. Sci. USA. 87:1990;8761-8765.
17. Schindler C., Darnell J.E. Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 64:1995;621-651.
18. Wang Q., Floyd-Smith G. The p69/71 2-5A synthetase promoter contains multiple regulatory elements required for interferon-α-induced expression. DNA Cell Biol. 16:1997;1385-1394.
19. Wang Q., Floyd-Smith G. Maximal induction of p69 2-5 A synthetase in Daudi cells requires cooperation between an ISRE and two IRF-1-like elements. Gene. 222:1998;83-90.
20. Wartmann M., Cella N., Hofer P., Groner B., Liu X., Hennighausen L., Hynes N.E. Lactogenic hormone activation of Stat5 and transcription of the beta-casein gene in mammary epithelial cells is independent of p42 ERK2 mitogen-activated protein kinase activity. J. Biol. Chem. 271:1996;31863-31868.
21. Wells V., Mallucci L. Expression of the 2-5A system during the cell cycle. Exp. Cell Res. 159:1985;27-36.
22. Wen Z., Zhong Z., Darnell J.E. Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell. 82:1995;241-250.
23. Witt P.I., Marié I., Robert N., Irizarry A., Borden E.C., Hovanessian A.G. Isoforms p69 and p100 of 2′,5′-oligoadenylate synthetase induced differentially by interferons in vivo and in vitro. J. Interferon Res. 13:1993;17-23.
24. Yu F., Floyd-Smith G. Protein kinase C is required for induction of 2′,5′-oligoadenylate synthetases. Exp. Cell Res. 234:1997;240-248.
25. Yu F., Floyd-Smith G. Protein synthesis dependent and independent induction of p69 2′-5′-oligoadenylate synthetase by interferon-α Cytokine. 1999;. in press.