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Volumn 88, Issue 2, 1999, Pages 160-167

Optimization of the host/vector system and culture conditions for production of penicillin acylase in Escherichia coli

Author keywords

Catabolite repression; Escherichia coli; Inclusion body; Penicillin acylase (PAC); Post translational processing

Indexed keywords

AMIDASE; CARBON; GLUCOSE; ISOPROPYL THIOGALACTOSIDE; PENICILLIN DERIVATIVE; PHENYLACETIC ACID DERIVATIVE;

EID: 0032865262     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(99)80195-9     Document Type: Article
Times cited : (7)

References (22)
  • 2
    • 0000903228 scopus 로고
    • Penicillin acylase: Enzyme production and its application in the manufacture of 6-APA
    • 2. Shewale, J. G., and Sivaraman, H.: Penicillin acylase: enzyme production and its application in the manufacture of 6-APA. Process Biochem., 24, 146-154 (1989).
    • (1989) Process Biochem. , vol.24 , pp. 146-154
    • Shewale, J.G.1    Sivaraman, H.2
  • 3
    • 0025100583 scopus 로고
    • Primary structure requirements for the maturation in vivo of penicillin acylase from Escherichia coli ATCC 11105
    • 3. Sizmann, D., Keilmann, C., and Bock, A.: Primary structure requirements for the maturation in vivo of penicillin acylase from Escherichia coli ATCC 11105. Eur. J. Biochem., 192, 143-151 (1990).
    • (1990) Eur. J. Biochem. , vol.192 , pp. 143-151
    • Sizmann, D.1    Keilmann, C.2    Bock, A.3
  • 4
    • 0027672619 scopus 로고
    • Molecular basis of the exclusive low-temperature synthesis of an enzyme in E. coli: Penicillin acylase
    • 4. Keilmann, C., Wanner, G., and Bock, A.: Molecular basis of the exclusive low-temperature synthesis of an enzyme in E. coli: penicillin acylase. Biol. Chem. Hoppe-Seyler, 374, 983-992 (1993).
    • (1993) Biol. Chem. Hoppe-Seyler , vol.374 , pp. 983-992
    • Keilmann, C.1    Wanner, G.2    Bock, A.3
  • 5
    • 0026705620 scopus 로고
    • Carbon regulation and the role in nature of the Escherichia coli penicillin acylase (pac) gene
    • 5. Merino, E., Balbas, P., Recillas, F., Becerril, B., Valle, F., and Bolivar, F.: Carbon regulation and the role in nature of the Escherichia coli penicillin acylase (pac) gene. Mol. Microbiol., 6, 2175-2182 (1992).
    • (1992) Mol. Microbiol. , vol.6 , pp. 2175-2182
    • Merino, E.1    Balbas, P.2    Recillas, F.3    Becerril, B.4    Valle, F.5    Bolivar, F.6
  • 6
    • 0027897709 scopus 로고
    • Studies of operational variables in batch mode for genetically engineered Escherichia coli cells containing penicillin acylase
    • 6. Bhattacharya, S., Gupta, V. S., Prabhune, A. A., SivaRaman, H., Debnath, M., and Ranjekar, P. K.: Studies of operational variables in batch mode for genetically engineered Escherichia coli cells containing penicillin acylase. Enzyme Microb. Technol., 15, 1070-1073 (1993).
    • (1993) Enzyme Microb. Technol. , vol.15 , pp. 1070-1073
    • Bhattacharya, S.1    Gupta, V.S.2    Prabhune, A.A.3    SivaRaman, H.4    Debnath, M.5    Ranjekar, P.K.6
  • 7
    • 0025700884 scopus 로고
    • High cell density culture of a recombinant Escherichia coli producing penicillin acylase in a membrane cell recycle fermentor
    • 7. Lee, Y. L. and Chang, H. N.: High cell density culture of a recombinant Escherichia coli producing penicillin acylase in a membrane cell recycle fermentor. Biotechnol. Bioeng., 36, 330-337 (1990).
    • (1990) Biotechnol. Bioeng. , vol.36 , pp. 330-337
    • Lee, Y.L.1    Chang, H.N.2
  • 8
    • 0027951891 scopus 로고
    • Kinetic study of penicillin acylase production by recombinant E. coli in batch cultures
    • 8. Ramirez, O. T., Zamora, R., Espinosa, G., Merino, E., Bolivar, F., and Quintero, R.: Kinetic study of penicillin acylase production by recombinant E. coli in batch cultures. Process Biochem., 29, 197-206 (1994).
    • (1994) Process Biochem. , vol.29 , pp. 197-206
    • Ramirez, O.T.1    Zamora, R.2    Espinosa, G.3    Merino, E.4    Bolivar, F.5    Quintero, R.6
  • 9
    • 0027908935 scopus 로고
    • Improved penicillin amidase production using a genetically engineered mutant of Escherichia coli ATCC 11105
    • 9. Robas, N., Zouheiry, H., Branlant, G., and Branlant, C.: Improved penicillin amidase production using a genetically engineered mutant of Escherichia coli ATCC 11105. Biotechnol. Bioeng., 41, 14-24 (1993).
    • (1993) Biotechnol. Bioeng. , vol.41 , pp. 14-24
    • Robas, N.1    Zouheiry, H.2    Branlant, G.3    Branlant, C.4
  • 10
    • 0028036517 scopus 로고
    • Periplasmic aggregation limits the proteolytic maturation of the Escherichia coli Penicillin G amidase Precursor polypeptide
    • 10. Scherrer, S., Robas, N., Zouheiry, H., Branlant, G., and Branlant, C.: Periplasmic aggregation limits the proteolytic maturation of the Escherichia coli Penicillin G amidase Precursor polypeptide. Appl. Microbiol. Biotechnol., 42, 85-91 (1994).
    • (1994) Appl. Microbiol. Biotechnol. , vol.42 , pp. 85-91
    • Scherrer, S.1    Robas, N.2    Zouheiry, H.3    Branlant, G.4    Branlant, C.5
  • 11
    • 0030916974 scopus 로고    scopus 로고
    • Localization and characterization of inclusion bodies in recombinant Escherichia coli cells overproducing penicillin G acylase
    • 11. Sriubolmas, N., Panbangred, W., Sriurairatana, S., and Meevootisom, V.: Localization and characterization of inclusion bodies in recombinant Escherichia coli cells overproducing penicillin G acylase. Appl. Microbiol. Biotechnol., 47, 373-378 (1997).
    • (1997) Appl. Microbiol. Biotechnol. , vol.47 , pp. 373-378
    • Sriubolmas, N.1    Panbangred, W.2    Sriurairatana, S.3    Meevootisom, V.4
  • 12
    • 0033526409 scopus 로고    scopus 로고
    • Genetic manipulation to identify limiting steps and develop strategies for high-level expression of penicillin acylase in Escherichia coli
    • 12. Chou, C. P., Vu, C.-C., Tseng, J.-H., Lin, M.-I, and Lin, H.-K.: Genetic manipulation to identify limiting steps and develop strategies for high-level expression of penicillin acylase in Escherichia coli. Biotechnol. Bioeng., 63, 263-272 (1999).
    • (1999) Biotechnol. Bioeng. , vol.63 , pp. 263-272
    • Chou, C.P.1    Yu, C.-C.2    Tseng, J.-H.3    Lin, M.-I.4    Lin, H.-K.5
  • 13
    • 0033037584 scopus 로고    scopus 로고
    • Manipulation of carbon assimilation with respect to expression of the pac gene for improving production of penicillin acylase in Escherichia coli
    • 13. Chou, C.P., Tseng, J.-H., Lin, M.-I, Lin, H.-K., and Yu, C.-C.: Manipulation of carbon assimilation with respect to expression of the pac gene for improving production of penicillin acylase in Escherichia coli. J. Biotechnol., 69, 27-38 (1999).
    • (1999) J. Biotechnol. , vol.69 , pp. 27-38
    • Chou, C.P.1    Tseng, J.-H.2    Lin, M.-I.3    Lin, H.-K.4    Yu, C.-C.5
  • 14
    • 0014674485 scopus 로고
    • A complementation analysis of the restriction and modification of DNA in Escherichia coli
    • 14. Boyer, H.W. and Roulland-Dussoix, D.: A complementation analysis of the restriction and modification of DNA in Escherichia coli. J. Mol. Biol., 41, 459-472 (1969).
    • (1969) J. Mol. Biol. , vol.41 , pp. 459-472
    • Boyer, H.W.1    Roulland-Dussoix, D.2
  • 15
    • 0017259809 scopus 로고
    • Regulation of penicillin acylase in Escherichia coli by cyclic AMP
    • 15. Gang, D.M. and Shaikh, K.: Regulation of penicillin acylase in Escherichia coli by cyclic AMP. Biochim. Biophys. Acta, 425, 110-114 (1976).
    • (1976) Biochim. Biophys. Acta , vol.425 , pp. 110-114
    • Gang, D.M.1    Shaikh, K.2
  • 16
    • 0015504855 scopus 로고
    • The isolation and kinetics of penicillin amidase from Escherichia coli
    • 16. Balasingham, K., Warburton, D., Dunnill, P., and Lilly, M. D.: The isolation and kinetics of penicillin amidase from Escherichia coli. Biochim. Biophys. Acta, 276, 250-256 (1972).
    • (1972) Biochim. Biophys. Acta , vol.276 , pp. 250-256
    • Balasingham, K.1    Warburton, D.2    Dunnill, P.3    Lilly, M.D.4
  • 17
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • 17. Towbin, H., Staehelin, T., and Gordon, J.: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76, 4350-4354 (1979).
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 21
    • 0025700668 scopus 로고
    • Production of recombinant human growth hormone in Escherichia coli: Expression of different precursors and physiological effects of glucose, acetate, and salts
    • 20. Bech-Jensen, E. and Carlsen, S.: Production of recombinant human growth hormone in Escherichia coli: expression of different precursors and physiological effects of glucose, acetate, and salts. Biotechnol. Bioeng., 36, 1-11 (1990).
    • (1990) Biotechnol. Bioeng. , vol.36 , pp. 1-11
    • Bech-Jensen, E.1    Carlsen, S.2
  • 22
    • 0028483693 scopus 로고
    • Effect of modified glucose uptake using genetic engineering techniques on high-level recombinant protein production in dense Escherichia coli cultures
    • 21. Chou, C.-H., Bennett, G. N., and San, K.-Y.: Effect of modified glucose uptake using genetic engineering techniques on high-level recombinant protein production in dense Escherichia coli cultures. Biotechnol. Bioeng., 44, 952-960 (1994).
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 952-960
    • Chou, C.-H.1    Bennett, G.N.2    San, K.-Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.