Current definitions of acute lung injury and the acute respiratory distress syndrome do not reflect their true severity and outcome

Intensive Care Medicine

Volumn 25, Issue 9, 1999, Pages 930-935

  Villar, Jesus ^a,b,c   Perez Mendez L ^a   Kacmarek, R M ^d,e  

^a HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA   (Spain)

^b MOUNT SINAI HOSPITAL   (Canada)

^c MERCER UNIVERSITY   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

Acute lung injury; ARDS; Definition; Outcome; Oxygenation index; Positive end expiratory pressure; Risk factor; Sepsis

Indexed keywords

ADOLESCENT; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; AIRWAY PRESSURE; ARTERIAL OXYGEN TENSION; ARTICLE; ARTIFICIAL VENTILATION; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; LUNG ALVEOLUS OXYGEN TENSION; LUNG INFILTRATE; LUNG INJURY; MAJOR CLINICAL STUDY; MALE; MORTALITY; POSITIVE END EXPIRATORY PRESSURE; PREVALENCE; PROGNOSIS; PROSPECTIVE STUDY; SPAIN; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY FUNCTION TESTS; SEVERITY OF ILLNESS INDEX; SPAIN; TERMINOLOGY; TREATMENT OUTCOME;

EID: 0032865241     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050984     Document Type: Article

References (26)

1. 1. Ashbaugh DG, Bigelow DB, Petty TL, Levine BE (1967) Acute respiratory distress in adults. Lancet 11:319-323
2. 2. Villar J, Slutsky AS (1989) The incidence of the adult respiratory distress syndrome. Am Rev Respir Dis 140: 814-816
3. 3. Murray JE, Matthay MA, Luce JM, Flick MR (1988) An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 138: 720-723
4. 4. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, LeGall JR, Morris A, Spragg R, the Consensus Committee (1994) The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149: 818-824
5. 5. Artigas A, Le Gall JR, Chastang CL, Carlet J, Blanch L, Fernandez R (1991) Clinical presentation, prognostic factors, and outcome of ARDS in the European Collaborative Study. A preliminary report. In: Zapol WM, Lemaire F (eds) Adult respiratory distress syndrome, Marcel Dekker, New York pp 37-63
6. 6. LeGall JR, Loirat P, Alperovitch A (1983) Simplified acute physiological score for intensive care patients. Lancet II:741
7. 7. Jardin F, Prost JF, Bazin M, Dessfond P, Ozier Y, Margairez A (1982) Modalités évolutives du syndrome de détresse respiratoire aigüe de l'adulte: valeur pronostique d'un indice de gravité tiré de l'oxygenation artériele. Nouv Press Med 11: 29-33
8. 8. Fry DE, Pearlstein L, Fulton RL, Polk HC (1980) Multiple system organ failure. The role of uncontrolled infection. Arch Surg 15: 136-140
9. 9. Bell RC, Coalson JJ, Smith JD, Johanson WG (1983) Multiple organ system failure and infection in adult respiratory distress syndrome. Ann Intern Med 99: 293-298
10. 10. Villar J, Manzano JJ, Blazquez MA, Quintana J, Lubillo S (1991) Multiple system organ failure in acute respiratory failure. J Crit Care 6: 75-80
11. 11.Heuser MD, Case LD, Ettinger WH (1992) Mortality in intensive care patients with respiratory disease: is age important? Arch Intern Med 152: 1683-1688
12. 12. Smith PEM, Gordon IJ (1986) An index to predict outcome in adult respiratory distresss syndrome. Intensive Care Med 12: 86-89
13. 13. Fowler AA, Hamman RF, Zerbe GO, Benson KM, HyersTM (1985) Adult respiratory distress syndrome: prognosis alter onset. Am Rev Respir Dis 132: 472-478
14. 14. Villar J, Slutsky A (1996) Is the outcome from acute respiratory distress syndrome improving? Curr Opinion Crit Care Med 2: 79-87
15. 15. Hudson LD, Milberg JA, Anardi D, Maunder RJ (1995) Clinical risks for development of the acute respiratory distress syndrome. Am J Respir Crit Care Med 151: 293-301
16. 16. Doyle RL, Szaflarski N, Modin GW, Wiener-Kronish JP, Matthay MA (1995) Identification of patients with acute lung injury. Predictors of mortality. Am J Respir Crit Care Med 152: 1818-1824
17. 17. Ferring M, Vincent JL (1997) Is outcome from ARDS related to the severity of respiratory failure? Eur Respir J 10: 1297-1300
18. 18. Amalo MBP, Barbas CSV, Medeiros DM, Magaldi RB, Schettino GPP, Lorenzi-Filho G et al (1998) Effect of a protective ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338: 347-354
19. 19. Stewart TE, Meade MO, Cook DJ, Granton JT, Hodder RV, Lapinsky SE et al (1998) Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome. N Engl J Med 338: 355-361
20. 20. Brochard L, Roudot-Thoraval F, Roupie E, Delclaux C, Chastre J, Fernandez-Mondejar E et al (1998) Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome. The Multicenter Trial Group on Tidal Reduction in ARDS. Am J Respir Crit Care Med 158: 1831-1838
21. 21. Brower R, Shanholtz C, Shade D, Fessler H, White P, Wiener C, et al (1997) Randomized controlled trial of small tidal volume ventilation in ARDS. Am J Respir Crit Care Med 155:A93
22. 22. Krafft P, Fridrich P, Pernerstorfer T, Fitzgerald RD, Koc D, Schneider B et al (1996) The acute respiratory distress syndrome: definitions, severity and clinical outcome. An analysis of 101 clinical investigations. Intens Care Med 22: 519-529
23. 23. Montgomery AB, Stager MA, Carrico CJ, Hudson LD (1985) Causes of mortality in patients with adult respiratory distress syndrome. Am Rev Respir Dis 132: 485-489
24. 24. Suchyta MR, Clemmer TP, Elliot CG, Orme JF, Weaver LK (1992) The adult respiratory distress syndrome: a report of survival and modifying factors. Chest 101: 1074-1079
25. 25. Hyers TM (1993) Prediction of survival and mortality in patients with adult respiratory distress. New Horizons 1: 466-470
26. 2 ratio and its differential response to conventional therapy. Chest 96: 849-851