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Volumn 265, Issue 2, 1997, Pages 87-94

Electron microscopy of assembly intermediates of the snRNP core: Morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core

Author keywords

Electron microscopy; Pre mRNA splicing; Protein protein interaction; Sm core proteins; snRNP

Indexed keywords

SMALL NUCLEAR RIBONUCLEOPROTEIN;

EID: 0031575412     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0713     Document Type: Article
Times cited : (26)

References (32)
  • 2
    • 0026022420 scopus 로고
    • The small nuclear ribonucleoproteins, SmB and B′, are products of a single gene
    • Chu J.-L, Elkon K. B. The small nuclear ribonucleoproteins, SmB and B′, are products of a single gene. Gene. 97:1991;311-312.
    • (1991) Gene , vol.97 , pp. 311-312
    • Chu, J.-L.1    Elkon, K.B.2
  • 3
    • 0029054375 scopus 로고
    • Identification and characterization of Uss1p(Sdb23p): A novel U6 snRNA-associated protein with significant similarity to core proteins of small ribonucleo proteins
    • Cooper et al. Identification and characterization of Uss1p(Sdb23p): A novel U6 snRNA-associated protein with significant similarity to core proteins of small ribonucleo proteins. EMBO J. 14:1995;2066-2075.
    • (1995) EMBO J. , vol.14 , pp. 2066-2075
    • Cooper1
  • 4
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam J. D., Lebovitz R. M., Roeder R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucl. Acids Res. 11:1983;1475-1489.
    • (1983) Nucl. Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 6
    • 0026744453 scopus 로고
    • Direct binding of small nuclear ribonucleoprotein G to the Sm site of small nuclear RNA. Ultraviolet light cross-linking of protein G to the AAU stretch within the Sm site (AAUUUGUGG) of U1 small nuclear ribonucleoprotein reconstituted in vitro
    • Heinrichs V., Hackl W., Lührmann R. Direct binding of small nuclear ribonucleoprotein G to the Sm site of small nuclear RNA. Ultraviolet light cross-linking of protein G to the AAU stretch within the Sm site (AAUUUGUGG) of U1 small nuclear ribonucleoprotein reconstituted in vitro. J. Mol. Biol. 227:1992;15-28.
    • (1992) J. Mol. Biol. , vol.227 , pp. 15-28
    • Heinrichs, V.1    Hackl, W.2    Lührmann, R.3
  • 7
    • 0029054377 scopus 로고
    • SnRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions
    • Hermann H., Fabrizio P., Raker V. A., Foulaki K., Hornig H., Brahms H., Lührmann R. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions. EMBO J. 14:1995;2076-2088.
    • (1995) EMBO J. , vol.14 , pp. 2076-2088
    • Hermann, H.1    Fabrizio, P.2    Raker, V.A.3    Foulaki, K.4    Hornig, H.5    Brahms, H.6    Lührmann, R.7
  • 8
    • 0027442904 scopus 로고
    • Purification and characterization of human autoantibodies directed to specific regions on U1RNA; Recognition of native U1RNP complexes
    • Hoet R. M., Kastner B., Lührmann R., van Venrooij W. J. Purification and characterization of human autoantibodies directed to specific regions on U1RNA; recognition of native U1RNP complexes. Nucl. Acids Res. 21:1993;5130-5136.
    • (1993) Nucl. Acids Res. , vol.21 , pp. 5130-5136
    • Hoet, R.M.1    Kastner, B.2    Lührmann, R.3    Van Venrooij, W.J.4
  • 9
    • 0027393013 scopus 로고
    • The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical
    • Jarmolowski A., Mattaj I. W. The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical. EMBO J. 12:1993;223-232.
    • (1993) EMBO J. , vol.12 , pp. 223-232
    • Jarmolowski, A.1    Mattaj, I.W.2
  • 10
    • 0024433788 scopus 로고
    • Electron microscopy of U1 small nuclear ribonucleoprotein particles: Shape of the particle and position of the 5′ RNA terminus
    • Kastner B., Lührmann R. Electron microscopy of U1 small nuclear ribonucleoprotein particles: shape of the particle and position of the 5′ RNA terminus. EMBO J. 8:1989;277-286.
    • (1989) EMBO J. , vol.8 , pp. 277-286
    • Kastner, B.1    Lührmann, R.2
  • 11
    • 0025254471 scopus 로고
    • Electron microscopy of small nuclear ribonucleoprotein (snRNP) particles U2 and U5: Evidence for a common structure-determining principle in the major U snRNP family
    • Kastner B., Bach M., Lührmann R. Electron microscopy of small nuclear ribonucleoprotein (snRNP) particles U2 and U5: evidence for a common structure-determining principle in the major U snRNP family. Proc. Natl Acad. Sci. USA. 87:1990;1710-1714.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 1710-1714
    • Kastner, B.1    Bach, M.2    Lührmann, R.3
  • 12
    • 0026596044 scopus 로고
    • Structure of the small nuclear RNP particle U1: Identification of the two structural protuberances with RNP-antigens A and 70 K
    • Kastner B., Kornstädt U., Bach M., Lührmann R. Structure of the small nuclear RNP particle U1: identification of the two structural protuberances with RNP-antigens A and 70 K. J. Cell Biol. 116:1992;839-849.
    • (1992) J. Cell Biol. , vol.116 , pp. 839-849
    • Kastner, B.1    Kornstädt, U.2    Bach, M.3    Lührmann, R.4
  • 14
    • 0025027317 scopus 로고
    • Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5
    • Lehmeier T., Foulaki K., Lührmann R. Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5. Nucl. Acids Res. 18:1990;6475-6484.
    • (1990) Nucl. Acids Res. , vol.18 , pp. 6475-6484
    • Lehmeier, T.1    Foulaki, K.2    Lührmann, R.3
  • 15
    • 0027988478 scopus 로고
    • CDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: Evidence for a direct D1-D2 interaction
    • Lehmeier T., Raker V., Hermann H., Lührmann R. cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: Evidence for a direct D1-D2 interaction. Proc. Natl Acad. Sci. USA. 91:1994;12317-12321.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 12317-12321
    • Lehmeier, T.1    Raker, V.2    Hermann, H.3    Lührmann, R.4
  • 16
    • 0000341684 scopus 로고
    • Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus
    • Lerner M. R., Steitz J. A. Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc. Natl Acad. Sci. USA. 76:1979;5495-5499.
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , pp. 5495-5499
    • Lerner, M.R.1    Steitz, J.A.2
  • 17
    • 0025173604 scopus 로고
    • Structure of spliceosomal snRNPs and their role in pre-mRNA splicing
    • Lührmann R., Kastner B., Bach M. Structure of spliceosomal snRNPs and their role in pre-mRNA splicing. Biochim. Biophys. Acta. 1087:1990;265-292.
    • (1990) Biochim. Biophys. Acta , vol.1087 , pp. 265-292
    • Lührmann, R.1    Kastner, B.2    Bach, M.3
  • 19
    • 78651189765 scopus 로고
    • On the nature of allosteric transitions: A plausible model
    • Monod J., Wyman J., Changeux J.-P. On the nature of allosteric transitions: a plausible model. J. Mol. Biol. 12:1965;88-118.
    • (1965) J. Mol. Biol. , vol.12 , pp. 88-118
    • Monod, J.1    Wyman, J.2    Changeux, J.-P.3
  • 20
    • 3142614471 scopus 로고
    • Molecular cloning of cDNA encoding Sm autoantigen: Derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles
    • Ohosone Y., Mimori T., Griffith A., Akizuki M., Homma M., Craft J., Hardin J. A. Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles. Proc. Natl Acad. Sci. USA. 86:1989;4249-4254.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 4249-4254
    • Ohosone, Y.1    Mimori, T.2    Griffith, A.3    Akizuki, M.4    Homma, M.5    Craft, J.6    Hardin, J.A.7
  • 21
    • 0030007060 scopus 로고    scopus 로고
    • The snRNP core assembly pathway: Identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro
    • Raker V. A., Plessel G., Lührmann R. The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro. EMBO J. 15:1996;2256-2269.
    • (1996) EMBO J. , vol.15 , pp. 2256-2269
    • Raker, V.A.1    Plessel, G.2    Lührmann, R.3
  • 22
    • 0023790339 scopus 로고
    • Molecular cloning of a cDNA encoding the human Sm-D antoantigen
    • Rokeach L. A., Haselby J. A., Hoch S. O. Molecular cloning of a cDNA encoding the human Sm-D antoantigen. Proc. Natl Acad. Sci. USA. 85:1988;4832-4836.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 4832-4836
    • Rokeach, L.A.1    Haselby, J.A.2    Hoch, S.O.3
  • 23
    • 0025375223 scopus 로고
    • Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B′ and their cognate RNAs
    • Scherly D., Boelens W., Dathan N. A., van Venrooij W. J., Mattaj I. W. Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B′ and their cognate RNAs. Nature. 345:1990;502-506.
    • (1990) Nature , vol.345 , pp. 502-506
    • Scherly, D.1    Boelens, W.2    Dathan, N.A.3    Van Venrooij, W.J.4    Mattaj, I.W.5
  • 24
    • 0029124901 scopus 로고
    • In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs
    • Ségault V., Will C. L., Sproat B. S., Lührmann R. In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs. EMBO J. 14:1995;4010-4021.
    • (1995) EMBO J. , vol.14 , pp. 4010-4021
    • Ségault, V.1    Will, C.L.2    Sproat, B.S.3    Lührmann, R.4
  • 25
    • 0028997105 scopus 로고
    • Sm and Sm-like proteins belong to a large family: Identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs
    • Séraphin B. Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs. EMBO J. 14:1995;2089-2098.
    • (1995) EMBO J. , vol.14 , pp. 2089-2098
    • Séraphin, B.1
  • 26
    • 0024386425 scopus 로고
    • Isolation of cDNA clones encoding the human SmB′/B autoimmune antigen and specifically reacting with human anti-Sm autoimmune sera
    • Sharpe N. G., Williams D. G., Howarth D. N., Coles B., Latchman D. S. Isolation of cDNA clones encoding the human SmB′/B autoimmune antigen and specifically reacting with human anti-Sm autoimmune sera. FEBS Letters. 250:1989;585-590.
    • (1989) FEBS Letters , vol.250 , pp. 585-590
    • Sharpe, N.G.1    Williams, D.G.2    Howarth, D.N.3    Coles, B.4    Latchman, D.S.5
  • 27
    • 0023478466 scopus 로고
    • CDNA cloning of the human U1 snRNA-associated A protein: Extensive homology between U1 and U2 snRNP-specific proteins
    • Sillekens P. T. G., Habets W. J., Beijer R. P., van Venrooij W. J. cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins. EMBO J. 6:1987;3841-3848.
    • (1987) EMBO J. , vol.6 , pp. 3841-3848
    • Sillekens, P.T.G.1    Habets, W.J.2    Beijer, R.P.3    Van Venrooij, W.J.4
  • 28
  • 30
    • 0026919628 scopus 로고
    • In vitro reconstitution of U1 and U2 snRNPs from isolated proteins and snRNA
    • Sumpter V., Kahrs A., Fischer U., Kornstädt U., Lührmann R. In vitro reconstitution of U1 and U2 snRNPs from isolated proteins and snRNA. Mol. Biol. Rep. 16:1992;229-240.
    • (1992) Mol. Biol. Rep. , vol.16 , pp. 229-240
    • Sumpter, V.1    Kahrs, A.2    Fischer, U.3    Kornstädt, U.4    Lührmann, R.5
  • 31
    • 0024827307 scopus 로고
    • Cloned human snRNP proteins B and B′ differ only in their carboxy-terminal part
    • van Dam A., Winkel I., Zijlstra-Baalbergen J., Smeenk R., Cuypers H. T. Cloned human snRNP proteins B and B′ differ only in their carboxy-terminal part. EMBO J. 8:1989;3853-3860.
    • (1989) EMBO J. , vol.8 , pp. 3853-3860
    • Van Dam, A.1    Winkel, I.2    Zijlstra-Baalbergen, J.3    Smeenk, R.4    Cuypers, H.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.