The Old World monkey DAZ (Deleted in AZoospermia) gene yields insights into the evolution of the DAZ gene cluster on the human Y chromosome

Human Molecular Genetics

Volumn 8, Issue 11, 1999, Pages 2017-2024

  Gromoll, Jörg ^a   Weinbauer, Gerhard F ^a   Skaletsky, Helen ^b,c   Schlatt, Stefan ^a   Rocchietti March, Massimilano ^a   Page, David C ^b,c   Nieschlag, Eberhard ^a  

^a INST OF REPRO MED OF THE UNIV   (Germany)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ARTICLE; AZOOSPERMIA; DNA LIBRARY; EVOLUTION; EXON; GENE CLUSTER; GENE DELETION; GENE STRUCTURE; HUMAN; MALE; MONKEY; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SPERMATID; SPERMATOCYTE; SPERMATOGONIUM; TESTIS; Y CHROMOSOME;

ANIMALS; BASE SEQUENCE; CALLITHRIX; CERCOPITHECIDAE; CHROMOSOMES, HUMAN, PAIR 3; DNA, COMPLEMENTARY; EVOLUTION, MOLECULAR; EXONS; GENE DUPLICATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES; HUMANS; MACACA FASCICULARIS; MALE; MOLECULAR SEQUENCE DATA; MONKEY DISEASES; OLIGOSPERMIA; PSEUDOGENES; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; SPERMATIDS; SPERMATOCYTES; SPERMATOGENESIS; TESTIS; Y CHROMOSOME;

EID: 0032862180     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/8.11.2017     Document Type: Article

References (31)

1. Tiepolo, L. and Zuffardi, O. (1976) Localization of factors controlling spermatogenesis in the non-fluorescent portion of the human Y chromosome long arm. Hum. Genet., 34, 119-124.
2. Reijo, R., Lee, T.Y., Salo, P., Alagappan, R., Brown, L.G., Rosenberg, M., Rozen, S., Jaffe, T., Straus, D., Hovatta, O., de la Chapelle, A., Silber, S. and Page, D.C. (1995) Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nature Genet., 10, 383-393.
3. Vogt, P., Edelmann, A., Kirch, S., Henegariu, O., Hirschmann, P., Kiesewetter, F., Köhn, F.M., Schill, W.B., Farah, S., Ramos, C., Hartmann, M., Hartschuh, W., Meschede, D., Behre, H.M., Castel, A., Nieschlag, E., Weidner, W., Gröne, H.J., Engel, W. and Haidl, G. (1996) Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11. Hum. Mol. Genet., 5, 933-943.
4. Simoni, M., Gromoll, J., Dworniczak, B., Rolf, C., Abshagen, K., Kamischke, A., Carani, C., Meschede, D., Behre, H.M., Horst, J. and Nieschlag, E. (1997) Screening for deletion of Y chromosome involving the DAZ (Deleted in Azoospermia) gene in azoospermia and severe oligozoospermia. Fertil. Steril., 67, 542-547.
5. Vogt, P. (1998) Human chromosome deletions in Yq11, AZF candidates and male infertility: history and update. Mol. Hum. Reprod., 4, 739-744.
6. Saxena, R., Brown, L.G., Hawkins, T., Alagappan, R.K., Skaletsky, H., Reeve, M.P., Reijo, R., Rozen, S., Dinulos, M.B., Disteche, C.M. and Page, D.C. (1996) The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. Nature Genet., 14, 292-299.
7. Shan, Z., Hirschmann, P., Seebacher, T., Edelmann, A., Jauch, A., Morell, J., Urbitsch, P. and Vogt, H.P. (1996) A SPGY copy homologous to the mouse gene DAZL1a and the Drosophila gene boule is autosomal and expressed only in human male gonad. Hum. Mol. Genet., 5, 2005-2011.
8. Yen, P.H., Chai, N.N. and Salido, E.C. (1996) The human autosomal gene DAZL1A: testis specificity and a candidate for male infertility. Hum. Mol. Genet. 5, 2013-2017.
9. Seboun, E., Barbaux, S., Bourgeron, T., Nishi, S., Agulnik, A., Egashira, M., Nikkawa, N., Bishop, C., Fellous, M., McElreavy, K. and Kasahara, M. (1997) Gene sequence, localization, and evolutionary conservation of DAZL1A, a candidate male sterility gene. Genomics, 41, 227-235.
10. Yen, P.H., Chai, N.N. and Salido, E.C. (1997) The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions. Mamm. Genome, 8, 756-759.
11. Carani, C., Gromoll, J., Brinkworth, M.H., Simoni, M., Weinbauer, G.F. and Nieschlag, E. (1997) cynDAZL1A: a cynomolgus homologue of the human autosomal DAZ gene. Mol. Hum. Reprod., 3, 479-483.
12. Gromoll, J., Simoni, M., Weinbauer, G.F. and Nieschlag, E (1998) Spermatogenesis-specific genes deleted in infertile men: DAZ/DAZH clinical aspects and animal models. In Stefanini, M., Boitani, C. and Galdieri, M. (eds), Testicular Function: From Gene Expression to Genetic Manipulation. Springer Verlag, Heidelberg, pp. 273-294.
13. Kumar, S. and Hedges, B. (1998) A molecular timescale for vertebrate evolution. Nature, 392, 917-920.
14. Cooke, H.J., Lee, M., Kerr, S. and Ruggiu, M. (1996) A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads. Hum. Mol. Genet., 5, 513-516.
15. Reijo, R., Seligman, J., Dinulos, M.B., Jaffe, T., Brown, L.G., Disteche, C.M. and Page, D.C. (1996) Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty. Genomics, 35, 346-352.
16. Houston, D.W., Zhang, J., Maines, J.Z., Wasserman, S.A. and King, M.L. (1998) A Xenopus DAZ-like gene encodes an RNA component of germ plasm and is a functional homologue of Drosophila boule. Development, 125, 171-180.
17. Menke, D.B., Mutter, G.L. and Page, D.C. (1997) Expression of DAZ, an Azoospermia Factor candidate, in human spermatogonia. Am. J. Hum. Genet., 60, 237-241.
18. Ruggiu, M., Speed, R., Taggart, M., McKay, S.J., Kilanowski, F., Saunders, P., Dorin, J. and Cooke, H.J. (1997) The mouse DAZL1a gene encodes a cytoplasmic protein essential for gametogenesis. Nature, 389, 73-77.
19. Eberhart, C.G., Maines, J.Z. and Wasserman, S.A. (1996) Meiotic cell cycle requirement for a fly homologue of human Deleted in Azoospermia. Nature, 381, 783-785.
20. Weinbauer, G.F. and Nieschlag, E. (1999) Testicular physiology of primates. In Weinbauer, G.F. and Korte, R. (eds), Reproduction in Nonhuman Primates: A Model System for Human Reproductive Physiology and Toxicology. Waxmann Verlag, Münster/New York, pp. 13-26.
21. Weinbauer, G.F. and Nieschlag, E. (1998) The role of testosterone in spermatogenesis. In Nieschlag, E. and Behre, H.M. (eds), Testosterone: Action, Deficiency, Substitution. 2nd edn. Springer Verlag, Heidelberg, pp. 143-168.
22. Zhengwei, Y., McLachlan, R.I., Bremner, W.J. and Wreford, N.G. (1997) Quantitative (stereological) study of the normal spermatogenesis in the adult monkey (Macaca fascicularis). J. Androl., 8, 681-687.
23. Gläser, B., Grützner, F., Willmann, U., Stanyon, R., Arnold, N., Taylor, K., Rietschel, W., Zeitler, S., Toder, R. and Schempp, W. (1998) Simian Y chromosomes: species-specific rearrangements of DAZ, RBM, and TSPY versus contiguity of PAR and SRY. Mamm. Genome, 9, 226-231.
24. Gläser, B., Yen, P.H. and Schempp, W. (1998) Fibre-FISH unravels apparently seven DAZ genes or pseudogenes clustered within a Y-chromosome region frequently deleted in azoospermic males. Chromosome Res., 6, 481-486.
25. Agulnik, A.I., Zharkikh, A., Boettger-Tong, H., Bourgon, T., Mc Elreavy, K. and Bishop, C.E. (1998) Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations. Hum. Mol. Genet., 9, 1371-1377.
26. Slee, R., Grimes, B., Speed, R.M., Taggart, M., Maguire, S.M., Ross, A., McGill, N.I., Saunders, P.T.K. and Cooke, H.J. (1999) A human DAZ transgene confers partial rescue of the mouse DAZ1 null phenotype. Proc. Natl. Acad. Sci. USA, 14, 8040-8045.
27. Maines, J.Z. and Wasserman, S.A. (1999) Post-transcriptional regulation of the meiotic Cdc25 protein Twine by the DAZ1 orthologue Boule. Nature Cell Biol., 1, 171-174.
28. Watanabe, Y., Shinozaki-Yabana, S., Chikashige, Y., Hiraoka, Y. and Yamamoto, M. (1997) Phosphorylation of RNA-binding protein controls cell cycle switch from mitotic to meiotic in fission yeast. Nature, 386, 187-190.
29. Niederberger, C., Agulnik, A.I., Cho, Y., Lamb, D. and Bishop, C.E. (1997) In situ hybridization shows that DAZL1a expression in mouse testis is restricted to premeiotic stages IV-VI of spermatogenesis. Mamm. Genome, 7, 277-278.
30. Seligmann, J. and Page, D.C. (1998) The DAZh gene is expressed in male and female embryonic gonads before germ cell sex differentiation. Biochem. Biophys. Res. Commun., 245, 878-882.
31. Venables, J.P. and Eperon, I.C. (1999) The roles of RNA-binding proteins in spermatogenesis and male infertility. Curr. Opin. Genet. Dev., 9, 346-354.