Passive sensitization of human airways increases responsiveness to leukotriene C4

European Respiratory Journal

Volumn 14, Issue 2, 1999, Pages 315-319

  Schmidt, D ^a   Ruehlmann, E ^a   Branscheid, D ^b   Magnussen, H ^b   Rabe, K F ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KRANKENHAUS GROSSHANSDORF   (Germany)

Author keywords

Allergen bronchial; Leukotrienes passive sensitization; Responsiveness histamine human airways

Indexed keywords

CARBACHOL; HISTAMINE; IMMUNOGLOBULIN E; ISOPRENALINE; LEUKOTRIENE C4;

ADULT; AGED; AIRWAY; ALLERGIC ASTHMA; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; BRONCHUS MUSCLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATORY CELL; MALE; PRIORITY JOURNAL; SENSITIZATION;

EID: 0032861368     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3003.1999.14b13.x     Document Type: Article

References (23)

1. Roquet A, Dahlen B, Kumlin M, et al. Combined antagonism of leukotrienes and histamine produces pre-dominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics. Am J Respir Crit Care Med 1997; 155: 1856-1863.
2. Björck T, Dahlén S-E. Leukotrienes and histamine mediate IgE-dependent contractions of human bronchi: pharmacological evidence obtained with tissues from asthmatic and nonasthmatic subjects. Pulm Pharmacol 1993; 6: 87-96.
3. Dunlop LS, Smith AP. Reduction of antigen-induced contraction of sensitized human bronchus in vitro by indomethacin. Br J Pharmacol 1975; 54: 495-497.
4. Watson N, Bodtke K, Coleman RA, et al. Role of IgE in hyperresponsiveness induced by passive sensitization of human airways. Am J Respir Crit Care Med 1997; 155: 839-844.
5. Black JL, Marthan R, Armour CL, Johnson PRA. Sensitization alters contractile responses and calcium influx in human airway smooth muscle. J Allergy Clin Immunol 1989; 84: 440-447.
6. Marthan R, Crevel H, Guenard H, Savineau JP. Responsiveness to histamine in human sensitized airway smooth muscle. Respir Physiol 1992; 90: 239-250.
7. Ben-Jebria A, Marthan R, Rossetti M, Savineau J-P. Effect of passive sensitization on the mechanical activity of human isolated bronchial smooth muscle induced by substance P, neurokinin A and VIP. Br J Pharmacol 1993; 109: 131-136.
8. Mitchell RW, Rühlmann E, Magnussen H, Leff AR, Rabe KF. Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity. Am J Physiol 1994; 267: 218-222.
9. Mitchell RW, Rabe KF, Magnussen H, Leff AR. Passive sensitization of human airways induces myogenic contractile responses in vitro. J Appl Physiol 1997; 83: 1276-1281.
10. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report: working party standardization of lung function/tests, European Community for Steel and Coal. Official statement of the European Respiratory Society. Eur Respir J 1993; 6: Suppl. 16, 5-40.
11. Rabe KF, Watson N, Dent G, et al. Inhibition of human airway sensitization by a novel monoclonal anti-IgE antibody, 17-9. Am J Respir Crit Care Med 1998; 157: 1429-1435.
12. Roberts JA, Thomson NC. The effect of passive sensitisation of human bronchial smooth muscle on in vitro sensitivity to histamine. Pulm Pharmacol 1989; 2: 103-105.
13. Dahlén S-E, Hedqvist P, Hammarström S, Samuelsson B. Leukotrienes are potent constrictors of human bronchi. Nature 1980; 288: 484-486.
14. 4. Eur J Pharmacol 1986; 125: 29-35.
15. 4, methacholine and histamine in normal and asthmatic subjects. Eur Respir J 1988; 1: 913-917.
16. Watson N, Rühlmann E, Magnussen H, Rabe KF. Histamine hypersensitivity induced by passive sensitization of human bronchus: effect of serum IgE depletion. Clin Exp Allergy 1998; 28: 679-685.
17. Solway J, Fredberg JJ. Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all. Am J Respir Cell Mol Biol 1997; 17: 144-146.
18. Jiang H, Halayko AJ, Liu X, Stephens NL. Ragweed sensitization-induced increase of myosin light chain kinase content in canine airway smooth muscle. Am J Respir Cell Mol Biol 1992; 7: 567-573.
19. Ammit AJ, Armour CL, Black JL. Myosin light chain kinase content is increased in human sensitized airway smooth muscle. Am J Respir Crit Care Med 1997; 155: A370.
20. Mitchell RW, Halayko AJ, Rabe KF, Leff AR. Relative content of smooth muscle α-actin, myosin heavy chain, and light chain kinase (MLCK) of human airways is unaffected by passive sensitization. Am J Respir Crit Care Med 1998; 157: A746.
21. Souhrada M, Souhrada JF. Immunologically induced alterations of airway smooth muscle cell membrane. Science 1984; 225: 723-725.
22. Ammit AJ, Bekir SS, Johnson PR, Hughes JM, Armour CL, Black JL. Mast cell numbers are increased in the smooth muscle of human sensitized isolated bronchi. Am J Respir Crit Care Med 1997; 155: 1123-1129.
23. Berger P, Walls AF, Marthan R, Tunon de Lara JM. Immunoglobulin E-induced passive sensitization of human airways: an immunohistochemical study. Am J Respir Crit Care Med 1998; 157: 610-616.