Heparin-binding EGF-like growth factor is expressed by mesangial cells and is involved in mesangial proliferation in glomerulonephritis

Journal of Pathology

Volumn 189, Issue 3, 1999, Pages 431-438

  Takemura, Tsukasa ^a   Murata, Yuka ^a   Hino, Satoshi ^a   Okada, Mitsuru ^a   Yanagida, Hidehiko ^a   Ikeda, Masaru ^a   Yoshioka, Kazuo ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Glomerulonephritis; Heparin binding EGF like growth factor; Human; Kidney; Mesangial cell; Rat

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; GLOMERULONEPHRITIS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MESANGIUM CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT;

ANIMALS; CELL CULTURE TECHNIQUES; COLLAGEN; DNA; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS; HUMANS; ISOANTIBODIES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0032860137     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199911)189:3<431::AID-PATH460>3.0.CO;2-I     Document Type: Article

References (38)

1. Floege J, Eng Y, Young B, Johnson R. Factors involved in the regulation of mesangial cell proliferation in vitro and in vivo. Kidney Int 1993; 39: S47-S54.
2. Yoshioka K, Maki S. Human IgA nephritis: immunocytochemical evidence of a chronic inflammatory proliferative disorder. Histol Histopathol 1995; 10: 203-212.
3. Johnson R, Floege J, Couser W, Alpers C. Role of platelet-derived growth factor in glomerular disease. J Am Soc Nephrol 1993; 4: 119-128.
4. Isaka Y, Fujiwara Y, Ueda N, Kaneda Y, Kamada T, Imai E. Glomerulo-sclerosis induced by in vivo transfection of transforming growth factor β or platelet derived growth factor in the rat kidney. J Clin Invest 1993; 92: 2597-2601.
5. Okuda S, Languino LR, Ruoslahti E, Border WA. Elevated expression of transforming growth factor-β and proteoglycan production in experimental glomerulonephritis; possible role in expansion of the mesangial extracellular matrix. J Clin Invest 1990; 86: 453-462.
6. Yoshioka K, Takemura T, Murakami K, et al. Transforming growth factor-β protein and mRNA in glomeruli in normal and diseased human kidneys. Lab Invest 1993; 68: 154-163.
7. Floege J, Eng E, Lindner V, et al. Rat glomerular mesangial cells synthesize basic fibroblast growth factor: release, up-regulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis. J Clin Invest 1992; 90: 2362-2369.
8. Ooi B, Cohen D, Veis J. Biology of the mesangial cell in glomerulonephritis - role of cytokines. Proc Soc Exp Biol Med 1996; 213: 230-237.
9. Yoshioka K, Takemura T, Murakami K, et al. In situ expression of cytokines in IgA nephritis. Kidney Int 1993; 44: 825-833.
10. Eitner F, Burg M, Weinhold B, et al. Role of interleukin-6 in mediating mesangial cell proliferation and matrix production in vivo. Kidney Int 1997; 51: 69-78.
11. Tesch G, Lan H, Atkins R, Nikolic-Paterson D. Role of interleukin-1 in mesangial cell proliferation and matrix deposition in experimental mesangioproliferative nephritis. Am J Pathol 1997; 151: 141-150.
12. Higashiyama S, Abraham J, Miller J, Fiddes J, Klagsbrun M. Heparin binding growth factor secreted by macrophage-like cell line that is related to EGF. Science 1991; 251: 936-939.
13. Blotnick S, Peoples G, Freeman M, Eberlein T, Klagsbrun M. T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts. Differential production and release by CD4+ and CD8+ T cells. Proc Natl Acad Sci USA 1994; 91: 2890-2894.
14. Higashiyama S, Abraham J, Klagsbrun M. Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate. J Cell Biol 1993; 122: 933-940.
15. Dluz S, Higashiyama S, Damm D, Abraham J, Klagsbrun M. Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells. Induction of mRNA levels and secretion of active mitogen. J Biol Chem 1993; 268: 18330-18334.
16. Temizer D, Yoshizumi M, Perrella M, Susanni E, Quertermous T, Lee M. Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells. J Biol Chem 1992; 267: 24892-24896.
17. Homma T, Sakai M, Yasuda T, Chen H-F, Coffey R Jr, Harris R. Heparin-binding epidermal growth factor-like growth factor mRNA increases in response to acute renal injury. J Clin Invest 1995; 96: 1018-1025.
18. Sakai M, Zhang M-Z, Homma T, et al. Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute injury. J Clin Invest 1997; 99: 2128-2138.
19. Takemura T, Kondo S, Homma T, Sakai M, Harris R. The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells. J Biol Chem 1997; 272: 31036-31042.
20. Takemura T, Hino S, Okada M, et al. Membrane bound HB-EGF (proHB-EGF) promotes renal tubular epithelial cell branching and motility. J Am Soc Nephrol 1997; 8: S1102 (Abstract).
21. Harris R, Hoover R, Jacobson H, Badr K. Evidence for glomerular actions of epidermal growth factor in the rat. J Clin Invest 1988; 82: 1028-1039.
22. Yoshida F, Isobe K, Matsuo S. In vivo effects of hyperglycemia on the outcome of acute mesangial injury in rats. J Lab Clin Med 1995; 125: 46-55.
23. Harper P, Robinson J, Hoover R, Wright T, Karnovsky M. Improved methods for culturing rat glomerular cells. Kidney Int 1984; 26: 875-880.
24. Miyazato H, Takemura T, Hino S, et al. Glucocorticoid-induced apoptosis of rat mesangial cells in culture. Clin Exp Nephrol 1998; 2: 12-17.
25. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
26. Abraham J, Damm D, Bajardi A, Miller J, Klagsbrun M, Ezekowitz R. Heparin-binding EGF-like growth factor: characterization of rat and mouse cDNA clones, protein domain conservation across species, and transcript expression in tissues. Biochem Biophys Res Commun 1993; 190: 125-133.
27. Sato M, Narita T, Kimura N, et al. Increased expression of integrins by heparin-binding EGF like growth factor in human esophageal cancer cells. Cancer Lett 1996; 102: 183-191.
28. Ito N, Kawata S, Tamura S, et al. Heparin-binding EGF-like growth factor is the potent mitogen for rat hepatocytes. Biochem Biophys Res Commun 1994; 198: 25-31.
29. Yoshizumi M, Kourembanas S, Temizer D, Cambria R, Quertermous T, Lee M. Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like growth factor gene in vascular endothelial cells. J Biol Chem 1992; 267: 9467-9469.
30. Hashimoto K, Higashiyama S, Asada H, et al. Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes. J Biol Chem 1994; 269: 20060-20066.
31. Miyazaki Y, Shinomura Y, Tsutsui S, et al. Oxidative stress increases gene expression of heparin-binding EGF-like growth factor and amphiregulin in cultured rat gastric epithelial cells. Biochem Biophys Res Commun 1996; 226: 542-546.
32. Polihronis M, Murphy B, Pease M, Power D. Heparin-binding epidermal growth factor-like growth factor, an immediate early gene for mesangial cells, is up-regulated in the Thyl.1 model. Exp Nephrol 1996; 4: 271-278.
33. Tan M, Lee Y, Shin S, Tsai J-H. Regulation of heparin binding epidermal growth factor like growth factor gene expression by LDL and oxidized LDL in rat mesangial cells. Biochem Biophys Res Commun 1994; 202: 1001-1008.
34. Tan M, Tsai J, Lee Y, Chen H, Shin S, Lai Y. Induction of heparin-binding epidermal growth factor-like growth factor mRNA by protein kinase C activators. Kidney Int 1994; 46: 690-695.
35. Aviezer D, Yayon A. Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF. Proc Natl Acad Sci U S A 1994; 91: 12173-12177.
36. Wilson C. Renal response to immunologic glomerular injury. In: Brenner B, ed. The Kidney. Philadelphia: W. B. Saunders, 1996; 1253-1391.
37. Border W, Noble N, Yamamoto T, et al. Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease. Nature 1992; 360: 361-364.
38. Johnson R, Raines E, Floege J, Yoshimura A, Prizl P, Alpers C. Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp Med 1992; 175: 1413-1416.