Synthesis of chiral carbocyclic ribonucleotides

Nucleosides and Nucleotides

Volumn 18, Issue 9, 1999, Pages 1911-1928

  Antle, Vincent D ^a,b   Caperelli, Carol A ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b MDS Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PURINE NUCLEOSIDE; PYRIMIDINE NUCLEOSIDE; RIBONUCLEOSIDE DERIVATIVE; RIBONUCLEOTIDE;

ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; NUCLEOTIDE METABOLISM; SYNTHESIS;

EID: 0032858061     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319908044853     Document Type: Article

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10. Abbreviations used: C-CMP, β-D-carbocyclic-1′-(1H-cytosin-1-yl)-ribonucleoside 5′-monophosphate; C-UMP, β-D-carbocyclic-1′-(1H-uracil-1-yl)-ribonucleoside 5′-monophosphate; C-GMP, β-D-carbocyclic-1′-(9H-guanin-9-yl) ribonucleoside 5′-monophosphate; C-IMP, β-D-carbocyclic-1′-(9H-hypoxanthin-9-yl) ribonucleoside 5′-monophosphate; C-rTMP, β-D-carbocyclic-1′-(1H-thymin-1-yl) ribonucleoside 5′-monophosphate; BOM, benzyloxymethyl; DEAD, diethyl azodicarboxylate; DMF, N, N-dimethylformamide; DMSO, dimethylsulfoxide; mCPBA, meto-chloro perbenzoic acid; TBAF, tetrabutylammonium fluoride; THF, tetrahydrofuran; TLC, thin layer chromatography; TMS, tetramethylsilane
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