Carbocyclic substrates and inhibitors for the bifunctional lyase of purine nucleotide biosynthesis

Nucleosides and Nucleotides

Volumn 15, Issue 11-12, 1996, Pages 1905-1926

  Schmitt, Laurent ^a   Caperelli, Carol A ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUMARIC ACID; GLUTAMIC ACID DERIVATIVE; LYASE; NUCLEOTIDE DERIVATIVE; RIBONUCLEOTIDE;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; PURINE SYNTHESIS;

EID: 0029906826     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319608002741     Document Type: Article

References (30)

1. 3-HOBT, 6-trifluoromethyl-1-hydroxybenzotriazole; mCPBA, meta-chloroperbenzoic acid; DEAD, diethyl azodicarboxylate; DCC, dicyclohexylcarbodiimide; ddATP, 2′,3′-dideoxyadenosine triphosphate; ddl, 2′,3′-dideoxyinosine; DMA, dimethylacetamide; GAICAR, glutaroaminoimidazole carboxamide ribonucleotide; C-GAICAR, carbocyclic glutaroaminoimidazole carboxamide ribonucleotide; SAICAR, succinoaminoimidazole carboxamide ribonucleotide; C-SAICAR, carbocyclic succinoamino imidazole carboxamide ribonucleotide; TBAF, tetrabutylammonium fluoride; TFA, trifluoroacetic acid; THF, tetrahydrofuran; TLC, thin layer chromatography; TMS, tetramethylsilane.
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