Selective cytotoxic effects of Doenjang (Korean Soybean Paste) fermented with Bacillus strains on human liver cell lines

Journal of Microbiology and Biotechnology

Volumn 9, Issue 4, 1999, Pages 504-508

  Choi, Myeong Rak ^b   Lim, Hyun Soo ^b   Chung, Yoon Ju ^b   Yoo, Eun Jeong ^b   Kim, Jong Kyu ^a  

^a Yeungnam University   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Cytotoxicity; Doenjang; Selectivity ratio

Indexed keywords

ARTICLE; BACILLUS; CELL STRAIN HEPG2; CYTOTOXICITY; FERMENTATION; HUMAN; LIVER CELL; SOYBEAN;

BACILLUS;

EID: 0032856419     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Chung, K.-S., K.-D. Yoon, D.-J. Kwon, S.-S. Hong, and S.-Y. Choi. 1997. Cytotoxicity testing of fermented soybean products with various tumour cells using MTT. Kor. J. Appl. Microbiol. Biotechnol. 25: 477-482.
2. Coward, L., N. C. Barnes, K. D. R. Stechell, and S. Barnes. 1993. Genistein, daizein, and their β-glycoside conjugates; antitumor isoflavones in soybean foods from American and Asian diets. J. Agric. Food Chem. 41: 1961-1965.
3. Han, E.-S., H.-J. Lee, and D.-H. Shon. 1993. Effects of amino acid composition and average hydrophobicity of soybean peptides on the concentration of serum cholesterol in rats. Kor. J. Food Sci. Technol. 25: 552-557.
4. Han, E.-S., H.-J. Lee, and D.-H. Shon. 1993. Effects of surface hydrophobicity of soybean peptides on the concentration or serum cholesterol and fecal steroid excretion in rats. Kor. J. Food Sci. Technol. 25: 571-575.
5. Hong, S.-S., K.-S. Chung, K.-D. Yoon, and Y.-J. Cho. 1996. Antimutagenic effect of solvent extracts of Korean fermented soybean products. Foods Biotechnol. 5: 263-267.
6. Hwang, J.-H. 1997. Angiotensin I converting enzyme inhibitory effect of Doenjang fermented by B. subtilis SCB-3 isolated from Meju, Korean traditional food. J. Kor. Soc. Food Sci. Nutr. 26: 775-783.
7. Kennedy, A. R. and J. B. Little. 1981. Effects of protease inhibitors on radiation transformation in vitro. Cancer Res. 41: 2103-2109.
8. Kim, J.-Y, Y.-S. Maeng, and K.-Y. Lee. 1995. Antioxidative effects of soybean extracts by using various solvents. Kor. J. Food Sci. Technol. 27: 635-639.
9. Kim, J.-K., O.-S. Shin, and S.-J. Lee. 1995. Optimal condition for pigmentation in Bacillus licheniformis SSA3 and cloning of a DNA fragment involved in pigment production. J. Microbiol. Biotechnol. 5: 22-25.
10. Kim, J.-K., S.-M. Park, and S.-J. Lee. 1995. Novel antimutagenic pigment produced by Bacillus licheniformis SSA3. J. Microbiol. Biotechnol. 5: 48-50.
11. Lee, J.-S. and H.-S. Cheigh. 1997. Antioxidative characteristics of isolated crude phenolics from soybean fermented foods (Doenjang). J. Kor. Soc. Food Sci. Nutr. 26: 376-382.
12. Lim, S.-Y., S.-H. Rhee, S.-Y. Yi, and K.-Y. Park. 1997. Growth inhibitory effect and changes in membrane phospolipid fatty acid composition on MG-63 and AZ-521 Human cancer cells by linoleic acid. J. Kor. Soc. Food Sci. Nutr. 26: 662-668.
13. Park, K.-Y, S.-H. Moon, H.-S. Cheigh, and H.-S. Baik. 1996. Antimutagenic effects of Doenjang (Korean Soy Paste). J. Food Sci. Nutr. 1: 151-158.
14. Peterson, G. and S. Barnes. 1991. Genistein inhibition of the human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene. Biochim. Biophys. Res. Commun. 179: 661-665.
15. Shamsuddin, A. M., A. M. Elsayed, and A. Ullah. 1988. Supression of large intestinal cancer in F344 rats by inositol hexaphosphate. Carcinogenesis 9: 577-582.
16. Shamsuddin, A. M., A. Ullah, and A. K. Charkravarthy. 1989. Inositol and inositol hexaphosphate supress cell proliferation and tumor formation in CD-1 mice. Carcinogenesis 10: 1461-1466.
17. Shin, Z.-I., C.-W. Ahn, H.-S. Nam, H.-J. Lee, H.-J. Lee, and T.-H. Moon. 1995. Fractionation of angiotensin converting enzyme (ACE) inhibitory peptides form soybean paste. Kor. J. Food Sci. Technol. 27: 230-234.
18. St. Clair, W. H., P. C. Billings, J. A. Carew, C. K. McGandy, P. Newberne, and A. R. Kennedy. Carcinogenesis in mice by dietary addition of the Bowman-Birk protease inhibitor. Cancer. Res. 50: 580-586.
19. Yang, E.-K., D.-H. Lee, S.-N. Park, T.-B. Choe, and J.-K. Park. 1997. Contraction behavior of collagen gel and fibroblasts activity in dermal equivalent model J. Microbiol. Biotechnol. 7: 267-271
20. Yoon, K.-D., D.-J. Kwon, S.-S. Hong, S.-I. Kim, and K.-S. Chung. 1996. Inhibitory effect of soybean and Korean fermented soybean products on the chemically induced mutagenesis. Kor. J. Appl. Microbiol. Biotechnol. 24: 525-528.
21. Yu, R., S.-A. Park, D.-K. Chung, H.-S. Nam, and Z.-I. Shin. 1996. Effect of soybean hydrolysate on hypertension in spontaneously hypertensive rats. J. Kor. Soc. Food Sci. Nutr. 25: 1031-1036.