The site of general anesthesia and cytochrome P450 monooxygenases: Occupation of the enzyme heme pocket by xenon and nitrous oxide

European Journal of Pharmacology

Volumn 381, Issue 1, 1999, Pages

  Labella, Frank S ^a   Stein, Douglas ^a   Queen, Gary ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Cytochrome P450; General anesthesia; Xenon

Indexed keywords

ALCOHOL; CYTOCHROME P450 ISOENZYME; HEME DERIVATIVE; NITROUS OXIDE; XENON;

ARTICLE; COMPETITIVE INHIBITION; DRUG POTENCY; ENZYME KINETICS; GENERAL ANESTHESIA; MOLECULAR MODEL; PRIORITY JOURNAL;

ANESTHETICS, GENERAL; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CYTOCHROME P-450 ENZYME SYSTEM; HEMEPROTEINS; MICROSOMES, LIVER; NITROUS OXIDE; PROTEIN BINDING; RATS; XENON;

EID: 0032856333     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00553-1     Document Type: Article

References (8)

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