Experimental rhinovirus 16 infection causes variable airway obstruction in subjects with atopic asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 4, 1999, Pages 1375-1380

  Grünberg, Katrien ^a,b   Timmers, Mieke C ^a,b   De Klerk, Eric P A ^a,b   Dick, Elliot C ^a,b   Sterk, Peter J ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE;

ADULT; AIRWAY OBSTRUCTION; ALLERGIC ASTHMA; ANTIBODY TITER; ARTICLE; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EXPERIMENTAL INFECTION; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOPATHOGENESIS; LUNG FUNCTION TEST; MALE; PRIORITY JOURNAL; RHINOVIRUS; RISK FACTOR; VIRUS INFECTION;

EID: 0032854447     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.4.9810083     Document Type: Article

References (31)

1. National Heart Lung and Blood Institute, National Institutes of Health. 1995. Global strategy for asthma management and prevention. NHLBI/WHO Workshop Report 95-3659.
2. Nicholson, K. G., J. Kent, and D. C. Ireland. 1993. Respiratory viruses and exacerbations of asthma in adults. Br. Med. J. 307:982-986.
3. Johnston, S. L., P. K. Pattemore, G. Sanderson, S. Smith, F. Lampe, L. Josephs, P. Symington, S. O'Toole, S. H. Myint, D. A. Tyrrell, et al. 1995. Community study of role of viral infections on exacerbations of asthma in 9-11 year old children. Br. Med. J. 310:1225-1229.
4. Cheung, D., E. C. Dick, M. C. Timmers, E. P. de Klerk, W. J. Spaan, and P. J. Sterk. 1995. Rhinovirus inhalation causes long-lasting excessive airway narrowing in response to methacholine in asthmatic subjects in vivo. Am. J. Respir Crit. Care Med. 152:1490-1496.
5. Grünberg, K., M. C. Timmers, H. H. Smits, E. P. A. De Klerk, E. C. Dick, W. J. M. Spaan, P. S. Hiemstra, and P. J. Sterk. 1997. Effects of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo. Clin. Exp. Allergy 27:36-45.
6. Grünberg, K., E. A. P. Kuijpers, E. P. A. De Klerk, H. W. F. M. de Gouw, A. C. M. Kroes, E. C. Dick, and P. J. Sterk, 1997. Effects of experimental rhinovirus 16 (RV16) infection on airway hyperresponsiveness to bradykinin in asthmatic subjects in vivo. Am. J. Respir. Crit. Care Med. 155:833-883.
7. Corrigan, C. J. and A. B. Kay. 1990. CD4 T-lymphocyte activation in acute severe asthma. Relationship to disease severity and atopic status. Am. Rev. Respir. Dis. 141:970-977.
8. Claman, D. M., H. A. Boushey, J. Liu, H. Wong, and J. V. Fahy. 1994. Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J. Allergy Clin. Immunol. 94:861-869.
9. Haahtela, T., M. Jarvinen, T. Kava, K. Kiviranta, S. Koskinin, K. Lehtonen, K. Nikander, T. Persson, K. Reinikainen, O. Selroos, et al. 1991. Comparison of a β-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. N. Engl. J. Med. 325:388-392.
10. Calhoun, W. J., E. C. Dick, L. B. Schwartz, and W. W. Busse. 1994. A common cold virus, rhinovirus 16, potentiates airway inflammation after segmental antigen bronchoprovocation in allergic subjects. J. Clin. Invest. 94:2200-2208.
11. Fraenkel, D. J., P. G. Bardin, G. Sanderson, F. Lampe, S. L. Johnston, and S. T. Holgate. 1995. Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects. Am. J. Respir. Crit. Care Med. 151:879-886.
12. Grünberg, K., H. H. Smits, M. C. Timmers, E. P. A. De Klerk, R. J. E. M. Dolhain, E. C. Dick, P. S. Hiemstra, and P. J. Sterk. 1997. Experimental rhinovirus 16 infection: effects on cell differentials and soluble markers in sputum in asthmatic subjects. Am. J. Respir. Crit. Care Med. 156:609-616.
13. Lockhart, A., A. T. Dinh-Xuan, J. Regnard, L. Cabanes, and R. Matran. 1992. Effect of airway Hood flow on airflow. Am. Rev. Respir. Dis. 146(Suppl.):S19-S23.
14. Carrol, N., J. Elliot, A. Morton, and A. James. 1993. The structure of large and small airways in nonfatal and fatal asthma. Am. Rev. Respir. Dis. 147:405-410.
15. Lemanske, R. F., Jr., E. C. Dick, C. A. Swenson, R. F. Vrtis, and W. W. Busse. 1989. Rhinovirus upper respiratory infection increases airway hyperreactivity and fate asthmatic reactions. J. Clin. Invest. 83:1-10.
16. Gwaltney, J. M., Jr., O. Hendley, F. G. Hayden, K. McIntosh, F. B. Hollinger, J. L. Melnick, and R. B. Turner. 1992. Updated recommendations for safety-testing of viral inocula used in volunteer experiments on rhinovirus colds. Prog. Med. Virol. 39:256-263.
17. Reddel, H. K., C. M. Salome, J. K. Peat, and A. J. Woolcock. 1995. Which index of expiratory flow is most useful in the management of stable asthma? Am. J. Respir. Crit. Care Med. 151:1320-1325.
18. Quanjer, P. H., G. J. Tammeling, J. E. Cotes, O. F. Pedersen, R. Peslin, and J. C. Yernault. 1993. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Eur. Respir. J. 6(Suppl. 16):5-40.
19. Sterk, P. J. L. M. Fabbri, P. H. Quanjer, D. W. Cockcroft, P. M. O'Byrne, S. D. Anderson, E. F. Juniper, and J. L. Malo. 1993. Airway responsiveness: standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Eur. Respir. J. 6(Suppl. 16):53-83.
20. Josephs, L. K., I. Gregg, M. A. Mullee, and S. T. Holgate. 1989. Nonspecific bronchial reactivity and its relationship to the clinical expression of asthma. A longitudinal study. Am. Rev. Respir. Dis. 140:350-357.
21. Gibson, P. G., B. J. O. Wong, M. J. E. Hepperle, P. A. Kline, A. Girdis-Gabardo, G. Guyatt, J. Dolovic, J. A. Denburg, E. H. Ramsdale, and F. E. Hargreave. 1992. A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid. Clin. Exp. Allergy 22:525-532.
22. Troyanov, S., H. Ghezzo, and J. Malo. 1994. Comparison of circadian variations using FEVI and peak expiratory flow rates among normal and asthmatic subjects. Thorax 49:775-780.
23. Pellegrino, R., P. J. Sterk, J. K. Sont, and V. Brusasco. 1998. Assessing the effect of deep inhalation on airway calibre: a novel approach to lung function in bronchial asthma and COPD. Eur. Respir J. 12:1219-1227.
24. Subauste, M. C., D. B. Jacoby, S. M. Richards, and D. Proud. 1995. Infection of a human respiratory epithelial cell line with rhinovirus: induction of cytokine release and modulation of susceptibility to infection by cytokine exposure. J. Clin. Invest. 96:549-557.
25. Terajima, M., M. Yamaya, K. Sekizawa, S. Okinaga, T. Suzuki, N. Yamada, K. Nakayama, T. Ohrui, T. Oshima, Y. Numazaki, and H. Sasaki. 1997. Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1β. Am. J. Physiol. 273:L749-L759.
26. James, A. L., P. D. Pare, and J. C. Hogg. 1989. The mechanics of airway narrowing in asthma. Am. Rev. Respir. Dis. 139:242-246.
27. Macklem, P. T. 1996. A theoretical analysis of the effect of airway smooth muscle loud on airway narrowing. Am. J. Respir. Crit. Care Med. 153:83-89.
28. Kraft, M., R. Djukanovic, S. Wilson, S. T. Holgate, and R. J. Martin. 1996. Alveolar tissue inflammation in asthma. Am. J. Respir. Crit. Care Med. 154:1505-1510.
29. Hamid, Q., Y. Song, T. C. Kotsimbos, E. Minshall, T. R. Bai, R. G Hegele, and J. C. Hogg. 1997. Inflammation of small airways in asthma. J. Allergy Clin. Immunol. 100:44-51.
30. Minshall, E. M., J. C. Hogg, and Q. A. Hamid. 1998. Cytokine mRNA expression in asthma is not restricted to the large airways. J. Allergy Clin. Immunol. 101:386-390.
31. Hegele, R. G., S. Hayashi, J. C. Hogg, and P. D. Pare. 1995. Mechanisms of airway narrowing and hyperresponsiveness in viral respiratory tract infections. Am. J. Respir. Crit. Care Med. 151:1659-1665.