Origin of selective inhibition of mitochondrial complex I by pyridinium-type inhibitor MP-24

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1413, Issue 2, 1999, Pages 63-69

  Iwata, Jun ^a   Miyoshi, Hideto ^a   Iwamura, Hajime ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Mitochondrial complex I; Pyridinium inhibitor; Respiratory chain; Structure activity relationship

Indexed keywords

N METHYL 4 [2 METHYL 2 (4 TERT BUTYLBENZYL)PROPYL]PYRIDINIUM; PYRIDINIUM DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CATTLE; CONCENTRATION RESPONSE; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY CHAIN; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX I; ENZYME INHIBITORS; MITOCHONDRIA; MITOCHONDRIA, HEART; NADH, NADPH OXIDOREDUCTASES; PYRIDINIUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032853222     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2728(99)00080-8     Document Type: Article

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