Serum and urinary nitrate levels in liver cirrhosis: Endotoxemia, renal function and hyperdynamic circulation

Journal of Hepatology

Volumn 25, Issue 5, 1996, Pages 707-714

  Campillo, Bernard ^a   Bories, Phuong Nhi ^a   Benvenuti, Christophe ^a   Dupeyron, Catherine ^a  

^a Hopital Albert Chenevier   (France)

Author keywords

Ascites; Cardiac output; Cirrhosis; Endotoxemia; Inflammatory proteins; Renal function; Serum and urine nitrate

Indexed keywords

HEMOGLOBIN; NITRATE; OROSOMUCOID;

ADULT; ARTICLE; ASCITES; ENDOTOXEMIA; FEMALE; HEART OUTPUT; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; LIVER CIRRHOSIS; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0030297486     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(96)80242-X     Document Type: Article

References (28)

1. 1. Stark ME, Szurszewski JH. Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroenterology 1992; 103: 1928-49.
2. 2. Bomzon A, Blendis LM. The nitric oxide hypothesis and the hyperdynamic circulation in cirrhosis. Hepatology 1994; 20: 1343-50.
3. 3. Sogni P, Moreau R, Gadano A, Lebrec D. The role of nitric oxide in the hyperdynamic circulatory syndrome associated with portal hypertension. J Hepatol 1995; 23: 218-24.
4. 4. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-12
5. 5. Vallance P, Moncada S. Hyperdynamic circulation in cirrhosis: a role for nitric oxide? Lancet 1991; 337: 776-8.
6. 6. Stuehr DJ, Marletta MA. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci USA 1985; 82: 7738-42.
7. 7. Marletta MA, Poksyn SY, Iyengar R, Leaf CD, Wishnok JS. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. Biochemistry 1988; 27: 8706-11.
8. 8. Bories PN, Bories C. Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase. Clin Chem 1995; 41: 904-5.
9. 9. Huntsman LL, Stewart DK, Barnes ST, Franklin SB, Colucousis JS, Hessel EA. Noninvasive two-dimensional echo Doppler determination of cardiac output in man: a clinical validation. Circulation 1983; 67: 593-602.
10. 10. Coats AJS. Doppler ultrasonic measurement of cardiac output: reproducibility and validation. Eur Heart J 1990; 11: Suppl 1: 1-49-61.
11. 11. Guarner C, Soriano G, Tomas A, Bulbena O, Novella MT, Balanzo J, Vilardell F, Mourelle M, Moncada S. Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia. Hepatology 1993; 18: 1139-43.
12. 12. Bird G, Severn A, Danesh BJ, Liew FY. Nitric oxide in alcohol-induced liver failure. J Hepatol 1993; 19: 316-22.
13. 13. Wagner DA, Schultz DS, Deen WM, Young VR, Tannenbaum SR. Metabolic fate of an oral dose of N-labeled nitrate in humans: effect of diet supplementation with ascorbic acid. Cancer Res 1983; 43: 1921-5.
14. 14. Lumsden AB, Henderson JM, Kutner MH. Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood in patients with cirrhosis. Hepatology 1988; 8: 232-6.
15. 15. Lin RS, Lee FY, Lee SD, Tsai YT, Lin HC, Lu RH, Hsu WC, Huang CC, Wang SS, Lo KJ. Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation. J Hepatol 1995; 22: 165-172.
16. 16. Le Moine O, Soupison T, Sogni P, Marchand A, Moreau R, Hadengue A, Goldman M, Deviere J, Lebrec D. Plasma endotoxin and tumour necrosis factor-α in the hyperkinetic state of cirrhosis. J Hepatol 1995; 23: 391-5.
17. 17. Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990; 265: 621-36.
18. 18. Kushner I. The acute phase response: an overview. Methods Enzymol 1988; 163: 373-83.
19. 19. Calver A, Harris A, Maxwell JD, Vallance P. Effect of local inhibition of nitric oxide synthesis on forearm blood flow and dorsal hand vein size in patients with alcoholic cirrhosis. Clin Sci 1994; 86: 203-8.
20. 20. Campillo B, Chabrier PE, Sediame S, Pelle G, Atlan G, Fouet P, Adnot S. Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced liver cirrhosis. Hepatology 1995; 22: 1423-9.
21. 21. Matsumoto A, Ogura K, Hirata Y, Kakoki M, Watanabe F, Takenaka K, Shiratori Y, Momomura SI, Omata M. Increased nitric oxide in the exhaled air of patients with decompensated liver cirrhosis. Ann Intern Med 1995; 123: 110-3.
22. 22. Forrest EH, Jones AL, Dillon JF, Walker J, Hayes PC. The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis. J Hepatol 1995; 23: 254-58.
23. 23. Kowalski HJ, Abelmann WH. The cardiac output at rest in Laennec's cirrhosis. J Clin Invest 1953; 32: 1025-33.
24. 24. Mashford ML, Mahon WA, Chalmers TC. Studies of the cardiovascular system in the hypotension of liver failure. N Engl J Med 1962; 267: 1071-4.
25. 25. Llach J, Ginès P, Arroyo V, Rimola A, Tito L, Badalamenti S, Jimenez W, Gaya J, Rivera F, Rodès J. Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites. Gastroenterology 1988; 94: 482-7.
26. 26. Smiesko V, Johnson PC. The arterial lumen is controlled by flow-related shear stress. NIPS 1993; 8: 34-8.
27. 27. Martin W, Smith JA, White DG. The mechanisms by which hemoglobin inhibits the relaxation of rabbit aorta induced by nitrovasodilatators, nitric oxide or bovine retractor penis inhibitory factor. Br J Pharmacol 1986; 89: 563-71.
28. 28. Anand IS, Chandrashekhar Y, Wander GS, Chawla LS. Endothelium-derived relaxing factor is important in mediating the high output state in chronic severe anemia. J Am Coll Cardiol 1995; 25: 1402-7.