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Volumn 23, Issue 8-9, 1999, Pages 892-902

Nitric oxide and liver diseases: Deleterious or beneficial?;Monoxyde d'azote et maladies du foie: Role deletere ou hepatoprotecteur?

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; OXYGEN RADICAL;

EID: 0032852392     PISSN: 03998320     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (107)
  • 1
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-6.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 2
    • 0027752805 scopus 로고
    • The L-arginine nitric oxide pathway
    • Moncada S, Higgs EA. The L-arginine nitric oxide pathway. N Engl J Med 1993;329:2002-12.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, E.A.2
  • 3
    • 0024390169 scopus 로고
    • Endothelium-derived relaxing and contracting factors
    • Furchgott RF, Vanhoutte PM. Endothelium-derived relaxing and contracting factors. FASEB J 1989;3:2007-18.
    • (1989) FASEB J , vol.3 , pp. 2007-2018
    • Furchgott, R.F.1    Vanhoutte, P.M.2
  • 4
    • 0027490697 scopus 로고
    • Nitric oxide: Foe or friend to the injured brain ?
    • Choi DW. Nitric oxide: foe or friend to the injured brain ? Proc Natl Acad Sci USA 1993;90:9741-3.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9741-9743
    • Choi, D.W.1
  • 5
    • 0028270719 scopus 로고
    • Regulation of biosynthesis of nitric oxide
    • Nathan C, Xie QW. Regulation of biosynthesis of nitric oxide. J Biol Chem 1994;269:13725-8.
    • (1994) J Biol Chem , vol.269 , pp. 13725-13728
    • Nathan, C.1    Xie, Q.W.2
  • 6
    • 0027947675 scopus 로고
    • New insights into the regulation of inductible nitric oxide synthesis
    • Morris SM, Billiar TR. New insights into the regulation of inductible nitric oxide synthesis. Am J Physiol 1994;266:E829-39.
    • (1994) Am J Physiol , vol.266
    • Morris, S.M.1    Billiar, T.R.2
  • 7
    • 0029131266 scopus 로고
    • Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducible nitric oxide synthase gene expression
    • Laskin DL, Rodriguez Del Valle M, Heck DE, Hwang SM, Ohnishi ST, Durham SK, et al. Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducible nitric oxide synthase gene expression. Hepatology 1995;22:223-34.
    • (1995) Hepatology , vol.22 , pp. 223-234
    • Laskin, D.L.1    Rodriguez Del Valle, M.2    Heck, D.E.3    Hwang, S.M.4    Ohnishi, S.T.5    Durham, S.K.6
  • 8
    • 0031594571 scopus 로고    scopus 로고
    • Interleukin Ibeta;-stimulated production of nitric oxide in rat hepatocytes is mediated through endogenous synthesis of interferon gamma
    • Schroeder RA, Gu JS, Kuo PC. Interleukin Ibeta;-stimulated production of nitric oxide in rat hepatocytes is mediated through endogenous synthesis of interferon gamma. Hepatology 1998;27: 7119.
    • (1998) Hepatology , vol.27 , pp. 7119
    • Schroeder, R.A.1    Gu, J.S.2    Kuo, P.C.3
  • 9
    • 0026705732 scopus 로고
    • Endogenous nitric oxide protects against platelet aggregation and cyclic flow variations in stenosed and endothelium-injured arteries
    • Yao SK, Ober JC, Krishnaswami A, Ferguson JJ, Anderson HV, Golino P, et al. Endogenous nitric oxide protects against platelet aggregation and cyclic flow variations in stenosed and endothelium-injured arteries. Circulation 1992;86:1302-9.
    • (1992) Circulation , vol.86 , pp. 1302-1309
    • Yao, S.K.1    Ober, J.C.2    Krishnaswami, A.3    Ferguson, J.J.4    Anderson, H.V.5    Golino, P.6
  • 10
    • 0026630603 scopus 로고
    • Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase
    • Clancy RM, Leszczynska-Piziak J, Abramson SB. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil Superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest 1992;90:1116-21.
    • (1992) J Clin Invest , vol.90 , pp. 1116-1121
    • Clancy, R.M.1    Leszczynska-Piziak, J.2    Abramson, S.B.3
  • 11
    • 0027535770 scopus 로고
    • Ischemia-reperfusion in feline small intestine: A role for nitric oxide
    • Kubes P. Ischemia-reperfusion in feline small intestine: a role for nitric oxide. Am J Physiol 1993;264:G143-9.
    • (1993) Am J Physiol , vol.264
    • Kubes, P.1
  • 12
    • 0001509578 scopus 로고
    • Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
    • Stuehr DJ, Marietta MA. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci USA 1985;82: 7738-42.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7738-7742
    • Stuehr, D.J.1    Marietta, M.A.2
  • 13
    • 0026500671 scopus 로고
    • Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular trypanosoma cruzi through a nitric oxide-dependent mechanism
    • Munoz-Fernandez MA, Fernandez MA, Fresno M. Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur J Immunol 1992;22:301-7.
    • (1992) Eur J Immunol , vol.22 , pp. 301-307
    • Munoz-Fernandez, M.A.1    Fernandez, M.A.2    Fresno, M.3
  • 14
    • 0026249262 scopus 로고
    • Cytokine and pneumocystis carinii-induced L-arginine oxidation by murine and human pulmonary alveolar macrophages
    • Sherman MP, Loro ML, Wong VS, Taskin DP. Cytokine and Pneumocystis carinii-induced L-arginine oxidation by murine and human pulmonary alveolar macrophages. J Protozool 1991;38: S234-6.
    • (1991) J Protozool , vol.38
    • Sherman, M.P.1    Loro, M.L.2    Wong, V.S.3    Taskin, D.P.4
  • 15
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43: 109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 17
    • 0027231742 scopus 로고
    • Nitric oxide-mediated apoptosis in murine peritoneal macrophage
    • Albina JE, Cui S, Mateo RB, Reichner JS. Nitric oxide-mediated apoptosis in murine peritoneal macrophage. J Immunol 1993;150: 5080-5.
    • (1993) J Immunol , vol.150 , pp. 5080-5085
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 18
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor WA, Squadrito GL. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol 1995;268:L699-722.
    • (1995) Am J Physiol , vol.268
    • Pryor, W.A.1    Squadrito, G.L.2
  • 19
    • 0029243372 scopus 로고
    • The role of nitric oxide in Kupffer cell-hepatocyte interactions
    • Harbrecht BG, Billiar TR. The role of nitric oxide in Kupffer cell-hepatocyte interactions. Shock 1995;3:79-87.
    • (1995) Shock , vol.3 , pp. 79-87
    • Harbrecht, B.G.1    Billiar, T.R.2
  • 20
    • 0031012401 scopus 로고    scopus 로고
    • The cellular pathogenesis of portal hypertension: Stellate cell contractility, endothelin and nitric oxide
    • Rockey D. The cellular pathogenesis of portal hypertension: stellate cell contractility, endothelin and nitric oxide. Hepatology 1997;25:1-5.
    • (1997) Hepatology , vol.25 , pp. 1-5
    • Rockey, D.1
  • 21
    • 0031941122 scopus 로고    scopus 로고
    • Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: Endothelial dysfunction in portal hypertension
    • Rockey DC, Chung JJ. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension. Gastroenterology 1998;114:344-51.
    • (1998) Gastroenterology , vol.114 , pp. 344-351
    • Rockey, D.C.1    Chung, J.J.2
  • 22
    • 0023697288 scopus 로고
    • Endotoxin modulation of hepatocyte secretory and cellular protein synthesis is mediated by Kupffer cells
    • West MA, Billiar TR, Mazuski JE, Curran RD, Cerra RJ, Simmons RL. Endotoxin modulation of hepatocyte secretory and cellular protein synthesis is mediated by Kupffer cells. Arch Surg 1988;123:1400-5.
    • (1988) Arch Surg , vol.123 , pp. 1400-1405
    • West, M.A.1    Billiar, T.R.2    Mazuski, J.E.3    Curran, R.D.4    Cerra, R.J.5    Simmons, R.L.6
  • 23
    • 0024573303 scopus 로고
    • An L-arginine-dependent mechanism mediates kupffer cell inhibition of hepatocyte protein synthesis in vitro
    • Billiar TR, Curran RD, Stuehr DJ, West MA, Bentz BG, Simmons RL. An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J Exp Med 1989;169:1467-72.
    • (1989) J Exp Med , vol.169 , pp. 1467-1472
    • Billiar, T.R.1    Curran, R.D.2    Stuehr, D.J.3    West, M.A.4    Bentz, B.G.5    Simmons, R.L.6
  • 25
  • 26
    • 0032054683 scopus 로고    scopus 로고
    • The role of nitric oxide in hepatic metabolism
    • Alexander B. The role of nitric oxide in hepatic metabolism. Nutrition 1998;14:376-90.
    • (1998) Nutrition , vol.14 , pp. 376-390
    • Alexander, B.1
  • 27
    • 0028799424 scopus 로고
    • The multiple organ dysfunction syndrome caused by endotoxin in rat: Attenuation of liver dysfunction by inhibitors of nitric oxide
    • Thiermermann C, Ruetten H, Wu CC, Vane JR. The multiple organ dysfunction syndrome caused by endotoxin in rat: attenuation of liver dysfunction by inhibitors of nitric oxide. Br J Pharmacol 1995;116:2845-51.
    • (1995) Br J Pharmacol , vol.116 , pp. 2845-2851
    • Thiermermann, C.1    Ruetten, H.2    Wu, C.C.3    Vane, J.R.4
  • 28
    • 0028887559 scopus 로고
    • Nitric oxide causes hyporeactivity to phenylephrine in isolated perfused livers from endotoxin-treated rats
    • Pastor CM, Billiar TR. Nitric oxide causes hyporeactivity to phenylephrine in isolated perfused livers from endotoxin-treated rats. Am J Physiol 1995;268:G177-182.
    • (1995) Am J Physiol , vol.268
    • Pastor, C.M.1    Billiar, T.R.2
  • 29
    • 0025111027 scopus 로고
    • Inhibition of L-arginine metabolism by NG-monomethyl-L-arginine in vivo promotes hepatic damage in response to lipopolysaccharide
    • Moncada S, Higgs EA, eds. Amsterdam: Elsevier
    • Billiar TR, Curran RD, Stuehr DJ, Hofmann K, Simmons RL, Inhibition of L-arginine metabolism by NG-monomethyl-L-arginine in vivo promotes hepatic damage in response to lipopolysaccharide. In: Moncada S, Higgs EA, eds. Nitric oxide from IL-arginine: a bioregulatory system. Amsterdam: Elsevier, 1990:275-85.
    • (1990) Nitric Oxide from IL-arginine: A Bioregulatory System , pp. 275-285
    • Billiar, T.R.1    Curran, R.D.2    Stuehr, D.J.3    Hofmann, K.4    Simmons, R.L.5
  • 30
    • 0031985033 scopus 로고    scopus 로고
    • Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock
    • Liaudet L, Rosselet A, Schaller MD, Markert M, Perret C, Feihl F. Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock. J Infect Dis 1998;177: 127-32.
    • (1998) J Infect Dis , vol.177 , pp. 127-132
    • Liaudet, L.1    Rosselet, A.2    Schaller, M.D.3    Markert, M.4    Perret, C.5    Feihl, F.6
  • 31
    • 0030918451 scopus 로고    scopus 로고
    • Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-a-induced apoptosis and toxicity in the liver
    • Saavedra JE, Billiar TR, Williams DL, Kim YM, Watkins SC, Keefer LK. Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-a-induced apoptosis and toxicity in the liver. J Med Chem 1997;40:1947-54.
    • (1997) J Med Chem , vol.40 , pp. 1947-1954
    • Saavedra, J.E.1    Billiar, T.R.2    Williams, D.L.3    Kim, Y.M.4    Watkins, S.C.5    Keefer, L.K.6
  • 32
    • 0031431194 scopus 로고    scopus 로고
    • Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia
    • Ou J, Carlos TM, Watkins SC, Saavedra JE, Keefer LK, Kim YM, et al. Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia. Nitric Oxide 1997;1:404-16.
    • (1997) Nitric Oxide , vol.1 , pp. 404-416
    • Ou, J.1    Carlos, T.M.2    Watkins, S.C.3    Saavedra, J.E.4    Keefer, L.K.5    Kim, Y.M.6
  • 34
  • 35
    • 0028254620 scopus 로고
    • Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia
    • Nishida J, McCursey RS, McDonnel D, Fox ES. Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia. Am J Physiol 1994;267:G1135-41.
    • (1994) Am J Physiol , vol.267
    • Nishida, J.1    McCursey, R.S.2    McDonnel, D.3    Fox, E.S.4
  • 36
    • 0030829599 scopus 로고    scopus 로고
    • Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats
    • Vos TA, Gouw ASH, Klock PA, Havinga R, Van Goor H, Huitena S, et al. Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats. Gastroenterology 1997; 113:1323-33.
    • (1997) Gastroenterology , vol.113 , pp. 1323-1333
    • Vos, T.A.1    Gouw, A.S.H.2    Klock, P.A.3    Havinga, R.4    Van Goor, H.5    Huitena, S.6
  • 37
    • 0029047742 scopus 로고
    • Role of nitric oxide in immunological liver damage in mice
    • Wang GS, Liu GT. Role of nitric oxide in immunological liver damage in mice. Biochem Parmacol 1995;49:1277-81.
    • (1995) Biochem Parmacol , vol.49 , pp. 1277-1281
    • Wang, G.S.1    Liu, G.T.2
  • 38
    • 0026666826 scopus 로고
    • Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen-mediated hepatic injury
    • Harbrecht BG, Billiar TR, Stadler J, Demetris AJ, Ochoa J, Curran RD, et al. Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen-mediated hepatic injury. J Leukoc Biol 1992;52:390-94.
    • (1992) J Leukoc Biol , vol.52 , pp. 390-394
    • Harbrecht, B.G.1    Billiar, T.R.2    Stadler, J.3    Demetris, A.J.4    Ochoa, J.5    Curran, R.D.6
  • 39
    • 0026340016 scopus 로고
    • Cytoprotective function of nitric oxide: Inactivation of superoxide radicals produced by human leukocytes
    • Rubanyi GM, Ho EH, Cantor EH, Lumma WC, Parker Botelho LH. Cytoprotective function of nitric oxide: inactivation of Superoxide radicals produced by human leukocytes. Biochem Biophys Res Commun 1991;181:1392-7.
    • (1991) Biochem Biophys Res Commun , vol.181 , pp. 1392-1397
    • Rubanyi, G.M.1    Ho, E.H.2    Cantor, E.H.3    Lumma, W.C.4    Parker Botelho, L.H.5
  • 40
    • 0028235972 scopus 로고
    • Inhibition of nitric oxide formation in vivo enhances superoxide release by the perfused liver
    • Bautista AP, Spitzer JJ. Inhibition of nitric oxide formation in vivo enhances Superoxide release by the perfused liver. Am J Physiol 1994;266:G783-8.
    • (1994) Am J Physiol , vol.266
    • Bautista, A.P.1    Spitzer, J.J.2
  • 41
    • 0022394280 scopus 로고
    • The importance of free radicals and catalytic metal ions in human diseases
    • Halliwell B, Gutteridge JMC. The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med 1985;8:89-193.
    • (1985) Mol Aspects Med , vol.8 , pp. 89-193
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 42
    • 0031578226 scopus 로고    scopus 로고
    • Oxidative stress increases hepatocytes iNOS gene transcription and promoter activity
    • Kuo PC, Abe KY, Schroeder RA. Oxidative stress increases hepatocytes iNOS gene transcription and promoter activity. Biochem Biophys Res Commun 1997;234:289-92.
    • (1997) Biochem Biophys Res Commun , vol.234 , pp. 289-292
    • Kuo, P.C.1    Abe, K.Y.2    Schroeder, R.A.3
  • 43
    • 0029033008 scopus 로고
    • Interleukin 1-induced production of nitric oxide inhibits benzenetriol-mediated oxidative injury in rat hepatocytes
    • Kuo PC, Abe KY. Interleukin 1-induced production of nitric oxide inhibits benzenetriol-mediated oxidative injury in rat hepatocytes. Gastroenterology 1995;109:206-16.
    • (1995) Gastroenterology , vol.109 , pp. 206-216
    • Kuo, P.C.1    Abe, K.Y.2
  • 44
    • 0030658979 scopus 로고    scopus 로고
    • Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression
    • Taylor BS, Kim YM, Wang Q, Shapiro RA, Billiar TR, Geller DA. Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression. Arch Surg 1997;132:1177-83.
    • (1997) Arch Surg , vol.132 , pp. 1177-1183
    • Taylor, B.S.1    Kim, Y.M.2    Wang, Q.3    Shapiro, R.A.4    Billiar, T.R.5    Geller, D.A.6
  • 45
    • 0031911630 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase attenuates peroxynitrite generation, but augments neutrophil accumulation in hepatic ischemia-reperfusion in rats
    • Liu P, Yin K, Nagele R, Wong PYK. Inhibition of nitric oxide synthase attenuates peroxynitrite generation, but augments neutrophil accumulation in hepatic ischemia-reperfusion in rats. J Pharmacol Exp Ther 1998;284:1139-46.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 1139-1146
    • Liu, P.1    Yin, K.2    Nagele, R.3    Wong, P.Y.K.4
  • 46
    • 0026346162 scopus 로고
    • Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
    • Petros A, Bennet D, Vallance P. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet 1991;338:1557-8.
    • (1991) Lancet , vol.338 , pp. 1557-1558
    • Petros, A.1    Bennet, D.2    Vallance, P.3
  • 47
    • 0028803686 scopus 로고
    • Kinetics of nitrosation of thiols by nitric oxide in the presence of oxygen
    • Kharitonov VG, Sundquist AR, Sharma VS. Kinetics of nitrosation of thiols by nitric oxide in the presence of oxygen. J Biol Chem 1995;270:28158-64.
    • (1995) J Biol Chem , vol.270 , pp. 28158-28164
    • Kharitonov, V.G.1    Sundquist, A.R.2    Sharma, V.S.3
  • 49
    • 0032062515 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthesis aggravates hepatic oxidative stress and enhanced superoxide dismutase inactivation in rats subjected to tourniquet shock
    • Vega VL, Maldonado M, Mardones L, Manriquez V, Vivaldi E, Roa J, et al. Inhibition of nitric oxide synthesis aggravates hepatic oxidative stress and enhanced superoxide dismutase inactivation in rats subjected to tourniquet shock. Shock 1998;9:320-8.
    • (1998) Shock , vol.9 , pp. 320-328
    • Vega, V.L.1    Maldonado, M.2    Mardones, L.3    Manriquez, V.4    Vivaldi, E.5    Roa, J.6
  • 51
    • 0028083328 scopus 로고
    • La matrice extracellulaire hépatique: Structure et régulation
    • Bedossa P. La matrice extracellulaire hépatique: structure et régulation. Gastroenterol Clin Biol 1994;18:556-67.
    • (1994) Gastroenterol Clin Biol , vol.18 , pp. 556-567
    • Bedossa, P.1
  • 52
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman SL. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 1993;328:1828-35.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 53
    • 12644298684 scopus 로고    scopus 로고
    • Neutrophil-derived superoxide anion induces lipid peroxydation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide
    • Casini A, Ceni E, Salzano R, Biondi P, Parola M, Galli A, et al. Neutrophil-derived superoxide anion induces lipid peroxydation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide. Hepatology 1997;25:361-7.
    • (1997) Hepatology , vol.25 , pp. 361-367
    • Casini, A.1    Ceni, E.2    Salzano, R.3    Biondi, P.4    Parola, M.5    Galli, A.6
  • 55
    • 0026638458 scopus 로고
    • Vitamin E dietary supplementation inhibits transforming growth factor b1 gene expression in the rat liver
    • Parola M, Muraca R, Dianzani I, Barrera G, Leonarduzzi G, Bendinelli P, et al. Vitamin E dietary supplementation inhibits transforming growth factor b1 gene expression in the rat liver. FEBS Lett 1992;308:267-70.
    • (1992) FEBS Lett , vol.308 , pp. 267-270
    • Parola, M.1    Muraca, R.2    Dianzani, I.3    Barrera, G.4    Leonarduzzi, G.5    Bendinelli, P.6
  • 56
    • 0028181393 scopus 로고
    • Stimulation of collagen alpha (I) gene expression is associated with lipid peroxidation in hepatocellular injury: A link to tissue tibrosis
    • Bedossa P, Houglum K, Trautwein C, Holstege A, Chojkier M. Stimulation of collagen alpha (I) gene expression is associated with lipid peroxidation in hepatocellular injury: a link to tissue tibrosis. Hepatology 1994;19:1262-71.
    • (1994) Hepatology , vol.19 , pp. 1262-1271
    • Bedossa, P.1    Houglum, K.2    Trautwein, C.3    Holstege, A.4    Chojkier, M.5
  • 57
    • 0031923590 scopus 로고    scopus 로고
    • Spatial and temporal dynamics of hepatic stellate cell activation during oxidant-stress-induced fibrogenesis
    • Montosi G, Garuti C, Iannone A, Pietrangelo A. Spatial and temporal dynamics of hepatic stellate cell activation during oxidant-stress-induced fibrogenesis. Am J Pathol 1998;152:1319-26.
    • (1998) Am J Pathol , vol.152 , pp. 1319-1326
    • Montosi, G.1    Garuti, C.2    Iannone, A.3    Pietrangelo, A.4
  • 58
    • 0028350768 scopus 로고
    • Alcohol and the liver: 1994 update
    • Lieber CS. Alcohol and the liver: 1994 update. Gastroenterology 1994;106:1085-1105.
    • (1994) Gastroenterology , vol.106 , pp. 1085-1105
    • Lieber, C.S.1
  • 59
    • 0026717172 scopus 로고
    • Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: Association of lipid peroxydation with liver fibrogenesis
    • Kaminura S, Gaal K, Britton RS, Bacon BR, Triadafilopoulos G, Tsukamoto H. Increased 4-hydroxynonenal levels in experimental alcoholic liver disease: association of lipid peroxydation with liver fibrogenesis. Hepatology 1992;16:448-53.
    • (1992) Hepatology , vol.16 , pp. 448-453
    • Kaminura, S.1    Gaal, K.2    Britton, R.S.3    Bacon, B.R.4    Triadafilopoulos, G.5    Tsukamoto, H.6
  • 60
  • 62
    • 0029145255 scopus 로고
    • Reduced antioxidative capacity in the liver mitochondria from bile duct ligated rats
    • Krahenbuhl S, Talos C, Lauterburg BH, Reichen J. Reduced antioxidative capacity in the liver mitochondria from bile duct ligated rats. Hepatology 1995;22:607-12.
    • (1995) Hepatology , vol.22 , pp. 607-612
    • Krahenbuhl, S.1    Talos, C.2    Lauterburg, B.H.3    Reichen, J.4
  • 64
    • 0029922315 scopus 로고    scopus 로고
    • Metals, oxidative stress, and hepatic fibrogenesis
    • Pietrangelo A. Metals, oxidative stress, and hepatic fibrogenesis. Semin Liver Dis 1996;13:13-30.
    • (1996) Semin Liver Dis , vol.13 , pp. 13-30
    • Pietrangelo, A.1
  • 65
    • 0345031751 scopus 로고    scopus 로고
    • Generation of reactive oxygen species and NO in the early phase of fibrosis: Effetcs of interferon-γ
    • Svegliati-Baroni G, de Jager-Frikken, Saccomanno S, Jansen PLM, Jezequel AM, Moshage H. Generation of reactive oxygen species and NO in the early phase of fibrosis: effetcs of interferon-γ (abstract). J Hepatol 1998;28(Suppl 1):83.
    • (1998) J Hepatol , vol.28 , Issue.SUPPL. 1 , pp. 83
    • Svegliati-Baroni, G.1    De Jager-Frikken2    Saccomanno, S.3    Jansen, P.L.M.4    Jezequel, A.M.5    Moshage, H.6
  • 67
    • 0028957207 scopus 로고
    • Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility
    • Rockey DC, Chung JJ. Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility. J Clin Invest 1995;95:1199-206.
    • (1995) J Clin Invest , vol.95 , pp. 1199-1206
    • Rockey, D.C.1    Chung, J.J.2
  • 68
    • 0030569525 scopus 로고    scopus 로고
    • Smooth muscle α-actin expression in rat hepatic stellate cell is regulated by nitric oxide and cGMP production
    • Kawada N, Kuroki T, Uoya M, Inoue M, Kobayashi K. Smooth muscle α-actin expression in rat hepatic stellate cell is regulated by nitric oxide and cGMP production. Biochem Biophys Res Commun 1996;229:238-42.
    • (1996) Biochem Biophys Res Commun , vol.229 , pp. 238-242
    • Kawada, N.1    Kuroki, T.2    Uoya, M.3    Inoue, M.4    Kobayashi, K.5
  • 69
  • 71
    • 24544462244 scopus 로고    scopus 로고
    • Different roles of free hydroxyl radicals, nitric oxide and tumor necrosis factor a in thioacetamide induced liver cirrhosis in rats
    • Bruck R, Shirin H, Aeed H, Zaidel L, Avni Y. Different roles of free hydroxyl radicals, nitric oxide and tumor necrosis factor a in thioacetamide induced liver cirrhosis in rats (abstract). Hepatology 1998;27:A1217.
    • (1998) Hepatology , vol.27
    • Bruck, R.1    Shirin, H.2    Aeed, H.3    Zaidel, L.4    Avni, Y.5
  • 72
    • 24544462243 scopus 로고    scopus 로고
    • 2b on biliary cirrhosis in the rat are mediated by nitric oxide
    • 2b on biliary cirrhosis in the rat are mediated by nitric oxide (abstract). Hepatology 1998;28:301A
    • (1998) Hepatology , vol.28
    • Muriel, P.1    Moreno, M.G.2
  • 73
    • 0027203305 scopus 로고
    • Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta
    • Vodovotz Y, Bogdan C, Xie QW, Nathan C. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. J Exp Med 1993;178:605-13.
    • (1993) J Exp Med , vol.178 , pp. 605-613
    • Vodovotz, Y.1    Bogdan, C.2    Xie, Q.W.3    Nathan, C.4
  • 74
    • 0029068496 scopus 로고
    • Down-regulation of transforming growth factor-beta gene expression by antisense oligodeoxynucleotides increases recombinant interferon-gamma-induced nitric oxide synthesis in murine peritoneal macrophages
    • Jun CD, Choi BM, Kim SU, Lee SY, Kim HM, Chung HT. Down-regulation of transforming growth factor-beta gene expression by antisense oligodeoxynucleotides increases recombinant interferon-gamma-induced nitric oxide synthesis in murine peritoneal macrophages. Immunology 1995;85:114-9.
    • (1995) Immunology , vol.85 , pp. 114-119
    • Jun, C.D.1    Choi, B.M.2    Kim, S.U.3    Lee, S.Y.4    Kim, H.M.5    Chung, H.T.6
  • 75
    • 0027233868 scopus 로고
    • Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life
    • Yoshizumi M, Perrella MA, Burnett JC Jr, Lee ME. Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. Circ Res 1993;73:205-209.
    • (1993) Circ Res , vol.73 , pp. 205-209
    • Yoshizumi, M.1    Perrella, M.A.2    Burnett J.C., Jr.3    Lee, M.E.4
  • 76
    • 0032920333 scopus 로고    scopus 로고
    • Monoxyde d'azote, vasodilatation et cirrhose: Un double (dés)équilibre
    • Sogni P, Moreau R, Lebrec D. Monoxyde d'azote, vasodilatation et cirrhose: un double (dés)équilibre. Gastroenterol Clin Biol 1999;23:101-4.
    • (1999) Gastroenterol Clin Biol , vol.23 , pp. 101-104
    • Sogni, P.1    Moreau, R.2    Lebrec, D.3
  • 77
    • 0024315708 scopus 로고
    • Effect of vasodilatators on hepatic microcirculation in cirrhosis: A study in the isolated perfused rat liver
    • Marteau P, Ballet F, Chazouillères O, Chrétien Y, Rey C, Petit D, et al. Effect of vasodilatators on hepatic microcirculation in cirrhosis: a study in the isolated perfused rat liver. Hepatology 1989;9:820-3.
    • (1989) Hepatology , vol.9 , pp. 820-823
    • Marteau, P.1    Ballet, F.2    Chazouillères, O.3    Chrétien, Y.4    Rey, C.5    Petit, D.6
  • 78
    • 0028878915 scopus 로고
    • Vessel- and target cell-specific actions of endothelin-1 and endothelin-3 in rat liver
    • Zhang JX, Bauer M, Clemens MG. Vessel- and target cell-specific actions of endothelin-1 and endothelin-3 in rat liver. Am J Physiol 1995;269:0269-77.
    • (1995) Am J Physiol , vol.269 , pp. 269-277
    • Zhang, J.X.1    Bauer, M.2    Clemens, M.G.3
  • 79
    • 0027190038 scopus 로고
    • The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus
    • Kawada N, Tran Thi TA, Klein H, Decker K. The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem 1993;213:815-23.
    • (1993) Eur J Biochem , vol.213 , pp. 815-823
    • Kawada, N.1    Tran Thi, T.A.2    Klein, H.3    Decker, K.4
  • 80
    • 0030794209 scopus 로고    scopus 로고
    • No-mediated vasodilatation in the rat liver. Role of hepatocytes and liver endothelial cells
    • Zhang B, Borderie D, Sogni P, Soubrane O, Houssin D, Calmus Y. NO-mediated vasodilatation in the rat liver. Role of hepatocytes and liver endothelial cells. J Hepatol 1997;26:1348-55
    • (1997) J Hepatol , vol.26 , pp. 1348-1355
    • Zhang, B.1    Borderie, D.2    Sogni, P.3    Soubrane, O.4    Houssin, D.5    Calmus, Y.6
  • 82
    • 0030729890 scopus 로고    scopus 로고
    • Role of nitric oxide in the regulation of the hepatic microcirculation in vivo
    • Bauer C, Walcher F, Kalweit U, Larsen R, Marzi I. Role of nitric oxide in the regulation of the hepatic microcirculation in vivo. S Hepatol 1997;27:1089-95.
    • (1997) S Hepatol , vol.27 , pp. 1089-1095
    • Bauer, C.1    Walcher, F.2    Kalweit, U.3    Larsen, R.4    Marzi, I.5
  • 83
    • 0031442394 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids
    • Shah V, Haddad FG, Garcia-Cardena G, Frangos JA, Mennone A, Groszmann RJ, et al. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J Clin Invest 1997;100:2923-30.
    • (1997) J Clin Invest , vol.100 , pp. 2923-2930
    • Shah, V.1    Haddad, F.G.2    Garcia-Cardena, G.3    Frangos, J.A.4    Mennone, A.5    Groszmann, R.J.6
  • 84
    • 0002430672 scopus 로고    scopus 로고
    • The evolution of knowledge on the physiopathology of portal hypertension
    • De Franchis eds.
    • Rodés J. The evolution of knowledge on the physiopathology of portal hypertension. In: De Franchis eds. Portal hypertension II 1996;18-29.
    • (1996) Portal Hypertension , vol.2 , pp. 18-29
    • Rodés, J.1
  • 85
    • 24544454360 scopus 로고    scopus 로고
    • Effect of chronic oral L-arginine treatment during the experimental induction of cirrhosis in the systemic and portal hemodynamics of cirrhotic rats
    • Lopez-Talavera JC, Martinez M, Genesca J, Gonzales A, Esteban R, Guardia J. Effect of chronic oral L-arginine treatment during the experimental induction of cirrhosis in the systemic and portal hemodynamics of cirrhotic rats (abstract). Hepatology 1996;24: 315A.
    • (1996) Hepatology , vol.24
    • Lopez-Talavera, J.C.1    Martinez, M.2    Genesca, J.3    Gonzales, A.4    Esteban, R.5    Guardia, J.6
  • 86
    • 0000379208 scopus 로고
    • Administration of L-arginine, the physiological precursor of nitric oxide, reduces portal perfusion pressure and ameliorates hepatic vascular hyperreactivity in experimental cirrhosis
    • Gupta TK, Groszmann RJ. Administration of L-arginine, the physiological precursor of nitric oxide, reduces portal perfusion pressure and ameliorates hepatic vascular hyperreactivity in experimental cirrhosis (abstract). Hepatology 1994;20:200A.
    • (1994) Hepatology , vol.20
    • Gupta, T.K.1    Groszmann, R.J.2
  • 87
    • 24544445471 scopus 로고    scopus 로고
    • Hepatic NO synthase is decreased in cirrhotic rats and correlates with hepatic functional impairment
    • Van De Casteele M, Reichen J. Hepatic NO synthase is decreased in cirrhotic rats and correlates with hepatic functional impairment (abstract). Hepatology 1997;26:280A.
    • (1997) Hepatology , vol.26
    • Van De Casteele, M.1    Reichen, J.2
  • 88
    • 0141647578 scopus 로고    scopus 로고
    • In vivo gene transfer of NO synthase reduces portal pressure in experimental cirrhosis in rats
    • Van De Casteele M, Janssens S, Roskams T, Desmet V, Nevens F, Fevery J. In vivo gene transfer of NO synthase reduces portal pressure in experimental cirrhosis in rats (abstract). Hepatology 1996;24:313A.
    • (1996) Hepatology , vol.24
    • Van De Casteele, M.1    Janssens, S.2    Roskams, T.3    Desmet, V.4    Nevens, F.5    Fevery, J.6
  • 90
    • 0030273532 scopus 로고    scopus 로고
    • Decreased constitutive hepatic nitric oxide synthase expression in secondary biliary fibrosis and its changes after roux-en Y choledocho-jejunostomy in the rat
    • Zimmermann H, Kurzen P, Klossner W, Renner EL, Marti U. Decreased constitutive hepatic nitric oxide synthase expression in secondary biliary fibrosis and its changes after Roux-en Y choledocho-jejunostomy in the rat. J Hepatol 1996;25:567-73.
    • (1996) J Hepatol , vol.25 , pp. 567-573
    • Zimmermann, H.1    Kurzen, P.2    Klossner, W.3    Renner, E.L.4    Marti, U.5
  • 91
    • 0005444805 scopus 로고    scopus 로고
    • Different expression of NO synthase in human cirrhotic liver specimens may be related to different mechanisms of portal hypertension
    • Roskams T, Van De Casteele M, Nevens F, Fevery J, Desmet V. Different expression of NO synthase in human cirrhotic liver specimens may be related to different mechanisms of portal hypertension (abstract). Hepatology 1996;24:314 A.
    • (1996) Hepatology , vol.24
    • Roskams, T.1    Van De Casteele, M.2    Nevens, F.3    Fevery, J.4    Desmet, V.5
  • 92
    • 0031682956 scopus 로고    scopus 로고
    • Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats
    • Gupta TK, Toruner M, Chung MK, Groszmann RJ. Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats. Hepatology 1998; 28:926-31.
    • (1998) Hepatology , vol.28 , pp. 926-931
    • Gupta, T.K.1    Toruner, M.2    Chung, M.K.3    Groszmann, R.J.4
  • 93
    • 24544464023 scopus 로고    scopus 로고
    • Impaired NOS activity associated with enhanced caveolin-1 binding to eNOS in experimental liver cirrhosis
    • Shah V, Cadelina G, Sessa WC, Groszmann RJ. Impaired NOS activity associated with enhanced caveolin-1 binding to eNOS in experimental liver cirrhosis (abstract). Hepatology 1998;28:510A.
    • (1998) Hepatology , vol.28
    • Shah, V.1    Cadelina, G.2    Sessa, W.C.3    Groszmann, R.J.4
  • 95
    • 0030198615 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in portal-hypertensive and cirrhotic rats
    • Kanwar S, Kubes P, Tepperman BL, Lee SS. Nitric oxide synthase activity in portal-hypertensive and cirrhotic rats. J Hepatol 1996;25;85-9.
    • (1996) J Hepatol , vol.25 , pp. 85-89
    • Kanwar, S.1    Kubes, P.2    Tepperman, B.L.3    Lee, S.S.4
  • 96
    • 0029114199 scopus 로고
    • The role of nitric oxide in the hyperdynamic circulatory' syndrome associated with portal hypertension
    • Sogni P, Moreau R, Gadano A, Lebrec D. The role of nitric oxide in the hyperdynamic circulatory' syndrome associated with portal hypertension. J Hepatol 1995;23:218-24.
    • (1995) J Hepatol , vol.23 , pp. 218-224
    • Sogni, P.1    Moreau, R.2    Gadano, A.3    Lebrec, D.4
  • 97
    • 0027513268 scopus 로고
    • Apoptosis
    • Cohen JJ. Apoptosis. Immunol Today 1993;14:126-30.
    • (1993) Immunol Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 99
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. Mechanisms and genes of cellular suicide. Science 1995;267:1445-9.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 100
    • 0031416664 scopus 로고    scopus 로고
    • Nitric oxide and apoptosis: Another paradigm for the double-edged role of nitric oxide
    • Dimmeler S, Zeiher AM. Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide. Nitric oxide 1997;1:275-81.
    • (1997) Nitric Oxide , vol.1 , pp. 275-281
    • Dimmeler, S.1    Zeiher, A.M.2
  • 102
    • 0028917191 scopus 로고
    • Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels
    • Gerano AM, Hortelano S, Alvarez A, Martinez C, Bosca L. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J Clin Invest 1995;95:1884-90.
    • (1995) J Clin Invest , vol.95 , pp. 1884-1890
    • Gerano, A.M.1    Hortelano, S.2    Alvarez, A.3    Martinez, C.4    Bosca, L.5
  • 103
    • 0028658374 scopus 로고
    • Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
    • Mannick JB, Asano K, Izumi K, Kieff E, Stamler JS. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell 1994;79:1137-46.
    • (1994) Cell , vol.79 , pp. 1137-1146
    • Mannick, J.B.1    Asano, K.2    Izumi, K.3    Kieff, E.4    Stamler, J.S.5
  • 104
    • 0031031148 scopus 로고    scopus 로고
    • Nitric oxide protects cultured rat hepatocytes from tnfα-induced apoptosis by inducing heat shock protein 70 expression
    • Kim YM, de Vera ME, Watkins SC, Billiar TR. Nitric oxide protects cultured rat hepatocytes from TNFα-induced apoptosis by inducing heat shock protein 70 expression. J Biol Chem 1997;272:1402-11.
    • (1997) J Biol Chem , vol.272 , pp. 1402-1411
    • Kim, Y.M.1    De Vera, M.E.2    Watkins, S.C.3    Billiar, T.R.4
  • 105
    • 0030662226 scopus 로고    scopus 로고
    • Nitric oxide prevents apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms
    • Kim YM, Talanian RV, Billiar TR. Nitric oxide prevents apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J Biol Chem 1997;272:31138-48.
    • (1997) J Biol Chem , vol.272 , pp. 31138-31148
    • Kim, Y.M.1    Talanian, R.V.2    Billiar, T.R.3
  • 106
    • 0026043528 scopus 로고
    • Systemic and splanchnic hemodynamic effects of moasidomine in rats with carbon tetrachloride-induced cirrhosis
    • Desmorat H, Vinel JP, Lahlou O, Pipy B, Calès P, et al. Systemic and splanchnic hemodynamic effects of moAsidomine in rats with carbon tetrachloride-induced cirrhosis. Hepatology 1991;13: 1181-4.
    • (1991) Hepatology , vol.13 , pp. 1181-1184
    • Desmorat, H.1    Vinel, J.P.2    Lahlou, O.3    Pipy, B.4    Calès, P.5


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