ATZ1993, an orally active and novel nonpeptide antagonist for endothelin receptors and inhibition of intimal hyperplasia after balloon denudation of the rabbit carotid artery

Japanese Journal of Pharmacology

Volumn 81, Issue 1, 1999, Pages 21-28

  Azuma, Hiroshi ^a   Sato, Jun ^a   Masuda, Hiroshi ^a   Goto, Moritaka ^a   Tamaoki, Satoru ^a   Sugimoto, Akiko ^a   Hamasaki, Hidehisa ^b   Yamashita, Haruo ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Grelan Pharmaceutical Co Ltd   (Japan)

Author keywords

ATZ1993; Balloon endothelial denudation; Inhibition of intimal hyperplasia; Novel endothelin receptor antagonist; Rabbit carotid artery

Indexed keywords

ATZ 1993; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERY INTIMA PROLIFERATION; ARTICLE; BALLOON; CAROTID ARTERY; CAROTID ARTERY SURGERY; CONTROLLED STUDY; DNA CONTENT; DRUG BLOOD LEVEL; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; HEART RATE; HUMAN; HUMAN TISSUE; INTIMA; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; ORAL DRUG ADMINISTRATION; PLACENTA; RABBIT; RADIORECEPTOR ASSAY; RECEPTOR AFFINITY; SWINE; TUNICA MEDIA; WEIGHT GAIN;

ADMINISTRATION, ORAL; ANGIOPLASTY, BALLOON; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CAROTID ARTERY INJURIES; CAROTID ARTERY, COMMON; ENDOTHELIN-1; HEART RATE; HUMANS; HYPERPLASIA; INDAZOLES; MALE; MUSCLE, SMOOTH, VASCULAR; RABBITS; RECEPTORS, ENDOTHELIN; SWINE; TUNICA INTIMA;

EID: 0032849939     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.81.21     Document Type: Article

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