Synthetic studies of an 18-membered antitumor macrolide, tedanolide. 5. Stereoselective synthesis of the C13 - C23 part via condensation of two fragments, C13 - C17 and C18 - C21, by taking advantage of the 3,4- dimethoxybenzyl protecting group

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 9, 1999, Pages 1288-1296

  Zheng, Bao Zhong ^a   Maeda, Hiroshi ^a   Mori, Michiko ^a   Kusaka, Shin Ichi ^a   Yonemitsu, Osamu ^a   Matsushima, Tomohiro ^b   Nakajima, Noriyuki ^c   Uenishi, Jun Ichi ^d  

^a OKAYAMA UNIVERSITY OF SCIENCE   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^d KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Evans asymmetric aldol reaction; Macrolide; Protecting group; Stereoselective synthesis; Wittig reaction

Indexed keywords

ANTINEOPLASTIC AGENT; MACROLIDE; TEDANOLIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; NUCLEAR OVERHAUSER EFFECT; POLYMERIZATION; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0032849512     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1288     Document Type: Article

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