Inhibition of sterol 14 α-demethylation of Candida albicans with NND-502, a novel optically active imidazole antimycotic agent

Medical Mycology

Volumn 37, Issue 5, 1999, Pages 351-355

  Niwano, Yoshimi ^a   Koga, H ^a   Kodama, H ^a   Kanai, K ^a   Miyazaki, T ^a   Yamaguchi, H ^b  

^a NIHON NOHYAKU CO LTD   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

Candida albicans; Ergosterol synthesis; Imidazole antimycotic; NND 502

Indexed keywords

[4 (2,4 DICHLOROPHENYL) 1,3 DITHIOLAN 2 YLIDENE](1 IMIDAZOLYL)ACETONITRILE; BIFONAZOLE; ERGOSTEROL; IMIDAZOLE DERIVATIVE; LANOCONAZOLE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; DEMETHYLATION; DERMATOMYCOSIS; DOSE RESPONSE; DRUG EFFICACY; DRUG PROTEIN BINDING; ENANTIOMER; ENZYME INHIBITION; NONHUMAN; STEREOCHEMISTRY; STEROL SYNTHESIS;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CYTOCHROME P-450 ENZYME SYSTEM; ERGOSTEROL; IMIDAZOLES; OXIDOREDUCTASES;

EID: 0032848941     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-280X.1999.00243.x     Document Type: Article

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