Clopidogrel and ticlopidine - Improvements on aspirin?

Drug and Therapeutics Bulletin

Volumn 37, Issue 8, 1999, Pages 59-61

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; HEPARIN; PHENPROCOUMON; TICLOPIDINE; WARFARIN; ANTITHROMBOCYTIC AGENT; DRUG DERIVATIVE;

ANGIOPLASTY; ATHEROSCLEROSIS; BONE MARROW TOXICITY; CLINICAL TRIAL; CORONARY STENT; DIARRHEA; DRUG ABSORPTION; DRUG CONTRAINDICATION; DRUG EXCRETION; GASTROINTESTINAL HEMORRHAGE; HEART INFARCTION; HUMAN; INTERMITTENT CLAUDICATION; NEUTROPENIA; ORAL DRUG ADMINISTRATION; PEPTIC ULCER; RASH; SHORT SURVEY; STROKE; THROMBOCYTE AGGREGATION INHIBITION; THROMBOTIC THROMBOCYTOPENIC PURPURA; VASCULAR DISEASE; CARDIOVASCULAR DISEASE; CONTROLLED CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; STENT;

ASPIRIN; CARDIOVASCULAR DISEASES; PLATELET AGGREGATION INHIBITORS; RANDOMIZED CONTROLLED TRIALS; STENTS; TICLOPIDINE;

EID: 0032846417     PISSN: 00126543     EISSN: None     Source Type: Journal    
DOI: 10.1136/dtb.1999.37859     Document Type: Short Survey

References (14)

1. Clopidogrel. Summary of product characteristics, EC. Sanofi Pharma Bristol-Myers Squibb SNC, July 1998.
2. Ticlopidine. Summary of product characteristics, UK. Sanofi Winthrop Limited, July 1998.
3. CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996; 348: 1329-39.
4. Hass WK, Easton JD, Adams Jr HP et al for the Ticlopidine Aspirin Stroke Study Group. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. N Engl J Med 1989; 321: 501-7.
5. Gandhi MM, Dawkins KD. Intracoronary stents. BWJ 1999; 318: 650-3.
6. Schomig A, Neumann F-J, Kastrati A et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med 1996; 334: 1084-9.
7. Leon MB, Baim DS, Popma JJ et al for the Stent Anticoagulation Restenosis Study Investigators. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. N Engl J Med 1998; 339: 1665-71.
8. Urban P, Macaya C, Rupprecht H-J et al for the MATTIS Investigators. Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients. The multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS). Circulation 1998; 98: 2126-32.
9. Mousa I, Oetgen M, Roubin G et al. Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation. Circulation 1999; 99: 2354-6.
10. Bennett CL, Weinberg PD, Rozenberg-Ben-Dror K, Yarnold PR, Kwaan HC, Green D. Thrombotic thrombocytopenic purpura associated with ticlopidine. A review of 60 cases. Ann Intern Med 1998; 128: 541-4.
11. Steinhubl SR, Tan WA, Foody JM, Topol EJ for the EPISTENT Investigators. Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting. JAMA 1999; 281: 806-10.
12. Drug-induced agranulocytosis. DTB 1997; 35: 49-52.
13. Managing carotid stenosis. DTB 1998; 36: 9-12.
14. Aspirin to prevent heart attack or stroke. DTB 1994; 32: 1-3.