Enhanced amyloidogenicity of sulfonated transthyretin in vitro, a hypothetical etiology of senile amyloidosis

Amyloid

Volumn 6, Issue 3, 1999, Pages 183-186

  Kishikawa, Masahiko ^a   Nakanishi, Toyofumi ^a   Miyazaki, Ayako ^a   Shimizu, Akira ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Amyloidogenicity; Familial amyloidotic polyneuropathy; Mass spectrometry; Posttranslational modification; Senile systemic amyloidosis; Sulfite; Transthyretin

Indexed keywords

AMYLOID PROTEIN; PREALBUMIN;

AMYLOIDOSIS; ARTICLE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SENILITY;

EID: 0032844667     PISSN: 13506129     EISSN: None     Source Type: Journal    
DOI: 10.3109/13506129909007324     Document Type: Article

References (10)

1. 1 Tawara S, Nakazato M, Kangawa K, Matsuo H and Araki S (1983). Identification of amyloid prealbumin variant in familial amyloidotic polyneuropathy (Japanese type). Biochem Biophys Res Commun 116, 880-888
2. 2 Benson MD (1995). Amyloid. In Scriver CR, Baudet AL, Sly WS and Valle D, (Eds) The Metabolic and Molecular Basis of Inherited Disease, 7th edn, Vol.III, pp. 4159-4191. (McGraw-Hill, New York)
3. 3 Westermark P, Sletten K, Johansson B and Cornwell III GG (1990). Fibril in senile systemic amyloidosis is derived from normal transthyretin. Proc Natl Acad Sci USA 87, 2843-2845
4. 4 Colon W and Kelly JW (1992). Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro. Biochemistry 31, 8654-8660
5. 5 Lai Z, Colon W and Kelly JW (1996). The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid. Biochemistry 35, 6470-6482
6. 6 Kishikawa M, Nakanishi T, Miyazaki A, Shimizu A, Nakazato M, Kangawa K and Matsuo H (1996). Simple detection of abnormal serum transthyretin from patients with familial amyloidotic polyneuropathy by high-performance liquid chromatography / electrospray ionization mass spectrometry using material precipitated with specific antiserum. J Mass Spectrom 31, 112-114
7. 7 Kishikawa M, Nakanishi T, Miyazaki A and Shimizu A (1999). A simple and reliable method of detecting variant transthyretins by multidimensional liquid chromatography coupled to electrospray ionization mass spectrometry. Amyloid: Int J Exp Clin Invest 6, 48-53
8. 8 Gregory RE and Gunnison AF (1984). Identification of plasma proteins containing sulfite-reactive disulfide bonds. Chem Biol Interaction 49, 55-69
9. 9 Kishikawa M, Nakanishi T, Miyazaki A, Hatanaka M, Shimizu A, Tamoto S, Ohsawa N, Hayashi H and Kanai M (1998). A new nonamyloid transthyretin variant, [G101S], detected by electrospray ionization / mass spectrometry. Hum Mutat, Mutation in Brief 12, 363
10. 2 and sulfite. Adv Exp Med Biol 197, 477-492