Altered Expression of Transforming Growth Factor-«in Hereditary Rat Renal Cell Carcinoma

Cancer Research

Volumn 51, Issue 11, 1991, Pages 2973-2978

  Walker, Cheryl ^a,c   Everitt, Jeffrey ^a   Whiteley, Laurence O ^a   Freed, Jerome J ^b   Knudson, Alfred G ^b  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b FOX CHASE CANCER CENTER   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; GENE MUTATION; GENETIC DISORDER; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; CARCINOMA, RENAL CELL; EPIDERMAL GROWTH FACTOR; KIDNEY; KIDNEY NEOPLASMS; PHENOTYPE; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0025781191     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Solleveld. H. A., and Boorman. G. A. Spontaneous renal lesions in five rat strains. Toxicol. Pathol., 14: 168-174, 1986.
2. Ekcr, R., and Mossige, J. A dominant gene for renal adenomas in the rat. Nature (Lond.). 189: 858-859. 1961.
3. Eker, R., Mossige. J., Johannessen, J. V., and Aars, H. Hereditary renal adenomas and adenocarcinomas in rats. Diagn. Histopathol. 4: 99-110. 1981.
4. Knudson. A. G. Hereditary cancers: Clues to mechanisms of carcinogenesis. Br. J. Cancer, 59: 661-666. 1989.
5. Yoshida, M. A., Ohyashiki, K., Ochi, H., Gibas, Z., Pontes. J. E., Prout, G. R., Haben, R., and Sandberg, A. A. Cytogenetic studies of tumor tissue from patients with nonfamilial renal cell carcinoma. Cancer Res., 46: 2119-2147, 1986.
6. Kovacs. G., Erlandsson, R., Boldog. F., Ingvarsson, S., Maller-Brechlin. R., Klein, G., and Samegi, J. Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc. Nati. Acad. Sci. USA. 85:1571-1575. 1988.
7. Naylor, S. L., Johnson. B. E., Minna. J. D., and Sakaguchi, A. Y. Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer. Nature (Lond.). 29:451-454. 1987.
8. Bergerheim. U., Nordenskjld, M., and Collins. V. P. Deletion mapping in human renal cell carcinoma. Cancer Res., 49: 1390-1396. 1989.
9. Cohen, A. J., Li, F. P., Berg, S., Marchetto, D. J., Tsai, S., Jacobs, S. C., and Brown. R. S. Hereditary renal-cell carcinoma associated with a chro mosomal translocation. N. Engl. J. Med. 301: 592-595. 1979.
10. Zbar. B., Brauch. H., Talmadge. C., and Linehan, M. Loss of alaelesof loci on the short arm of chromosome 3 in renal cell carcinoma. Nature (Lond.). 327: 721-724, 1987.
11. Kovacs. G., and Frisch. S. Clonal chromosome abnormalities in tumor cells from patients with sporadic renal cell carcinomas. Cancer Res., 49:651-659, 1989.
12. Yoshida, M. A., Ikeuchi. T., Tachibana. T., Takagi, K., Moriyama, M., and Tonomura, A. Rearrangements of chromosome 3 in nonfamilial renal cell carcinomas from Japanese patients. Jpn. J. Cancer Res., 79: 600-607. 1988.
13. Derynck. R., Goeddel. D. V., Ullrich. A., Gutterman. J. U., Williams. R. D., Bringman, T. S., and Berger. W. H. Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors. Cancer Res., 47: 707-712, 1987.
14. Mydlo, J. H., Michaeli. J., Cordon-Cardo. C., Goldenberg. A. S., Heston, W. D. W., and Fair. W. R. Expression of transforming growth factor and epidermal growth factor receptor messenger RNA in neoplastic and nonneoplastic human kidney tissue. Cancer Res., 49: 3407-3411, 1989.
15. Cornelia, L. G., Sargent, E. R., Wade. T. P., Anglard. P., Linehan, W. M., and Kasid, A. Expression of transforming growth factor in normal human adult kidney and enhanced expression of transforming growth factors a and /il in renal cell carcinoma. Cancer Res., 49: 6972-6975. 1989.
16. Petrides. P. E., Bock. S., Bovens. J., Hofmann. R., and Jakse, G. Modulation of pro-epidermal growth factor, pro-transforming growth factor and epi dermal growth factor receptor gene expression in human renal carcinomas. Cancer Res., 50: 3934-3939. 1990.
17. Derynck, R. Transforming growth factor a. Cell, 54: 593-595, 1988.
18. Pike, L. J., Marquardt, H., Todaro, G. J., Galiis, B., Casnellie, J. E., Bomstein, P., and Krebs, E. G. Transforming growth factor and epidermal growth factor stimulate the phosphorylation of a synthetic, tyrosine-contain-ing peptide in a similar manner. J. Biol. Chem., 257: 14628-14631,1982.
19. Massague, J. Epidermal growth factor-like transforming growth factor. H. Interaction with epidermal growth factor receptors in human placenta mem- 41. branes and A431 cells. J. Biol. Chem., 258: 13614-13620,1983.
20. Rosenthal, A., Lindquist, P. B., Bringman, T. S., Goeddel, D. V., and Derynck, R. Expression in rat fibroblasts of a human transforming growth 42. factor-a cDNA results in transformation. Cell, 46:301-309,1986.
21. Lee, D. C., Rose, T. M., Webb, N. R., and Todaro, G. J. Cloning and sequence analysis of a cDNA for rat transforming growth factor-a. Nature (Lond.), 515: 489-491,1985.
22. Han, V. K. M., Hunter, E. S., Pratt, R. M., Zendegui, J. G., and Lee, D. C. Expression of rat transforming growth factor alpha mRNA during development occurs predominantly in the maternal decidua. Mol. Cell. Biol., 7: 2335-2343, 1987.
23. Wilcox, J. N., and Derynck, R. Developmental expression of transforming growth factors alpha and beta in mouse fetus. Mol. Cell. Biol., 8:3415-3422, 1988.
24. Wilcox, J. N., and Derynck, R. Localization of cells synthesizing transforming growth factor-alpha mRNA in the mouse brain. J. Neurosci., 8: 1901-1904, 1988.
25. Skinner, M. K., Takacs, K., and Coffey, R. J. Transforming growth factor-alpha gene expression and action in the seminiferous tubule: Peritubular cell-Sertoli cell interactions. Endocrinology, 124:845-854, 1989.
26. Coffey, R. J., Derynck, R., Wilcox, J. N., Bringman, T. S., Goustin, A. S., Moses, H. L., and Pittelkow, M. R. Production and autoinduction of transforming growth factor-alpha in human keratinocytes. Nature (Lond.), 528: 817-820, 1987.
27. Madtes, D. K., Raines, E. W., Sakariassen, K. S., Assoian, R. K., Spom, M. B., Bell, G. I., and Ross, R. Induction of transforming growth factor-alpha in activated human alveolar macrophages. Cell, 55: 285-293, 1988.
28. Samsoondar, J., Kobrin, M. S., and Kudlow, J. E. Alpha-transforming growth factor secreted by untransformed bovine anterior pituitary cells in culture. J. Biol. Chem., 261:14408-14413,1986.
29. Valverius, E. M., Bates, S. E., Stampfer, M. R., Clark, R., McCormick, F., Salomon, D. S., Lippman, M. E., and Dixon, R. B. Transforming growth factor-a production and EGF receptor expression in normal and oncogene transformed human mammary epithelial cells. Mol. Endocrinol., 5: 203-214, 1989.
30. Sargent, E. R., Gomella, L. G., Belldegrun, A., Linehan, W. M., and Kasid, A. Epidermal growth factor receptor gene expression in normal human 52. kidney and renal cell carcinoma. J. Urol., 52:1364-1368,1989.
31. Yao, M., Shuin, T., Misaki, H., and Kubota, Y. Enhanced expression of c-myc and epidermal growth factor receptor (C-er6B-l) genes in primary human renal cancer. Cancer Res., 48:6753-6757,1988.
32. Concolino, G., Lubrano, C., Santonati, A., DiSilverio, P., Catizone, A., and Conti, C. Epidermal growth factor (EGF) binding by normal and neoplastic human renal tissue. J. Tumor Marker Oncol., 4:89-97, 1989.
33. Xu, Y-H., Richert, N., Ito, S., Merlino, G. T., and Pastan, I. Characterization 55. of epidermal growth factor receptor gene expression in malignant and normal human cell lines. Proc. Natl. Acad. Sci. USA, 81:7308-7312,1984.
34. Freeman, M. R., Washecka, R., and Chung, L. W. K. Aberrant expression of epidermal growth factor receptor and HER-2 {erb%-2) messenger RNAs in human renal cancers. Cancer Res., 49:6221-6225, 1989.
35. Johannessen, J. V., Eker, R., and Sobrinho-Simoes, M. The ultrastructure of hereditary renal adenomas and adenocarcinomas in rats. J. Submicrosc. Cytol., 72:463-473,1980.
36. Kimchi, A., Wang, X-F., Weinberg, R. A., Cheifetz, S., and Massague, J. Absence of TGF-/9 receptors and growth inhibitory responses in retinoblastoma cells. Science (Washington DC), 240: 196-199,1988.
37. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Uppert, M., Nakamura, Y., White, R., Smits, A. M. M., and Bos, J. L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 519:525-532, 1988.
38. Bos, J. L., Fearon, E. R., Hamilton, S. R., Verlaan-de Vries, M., van Boom, J. H., van der Eb, A. J., and Vogelstein, B. Prevalence of ras gene mutations in human colorectal cancers. Nature (Lond.), 527:293-297, 1987.
39. Forrester, K., Almoguera, C., Han, K., Grizzle, W. E., and Perucho, M. Detection of high incidence of K-ros oncogenes during human colon tumorigenesis. Nature (Lond.), 527: 298-303, 1987.
40. Freed, J. J., Howard, S., Lerro, A., Dodson, L., Scsok, D., and Knudson, A. G., Jr. Hereditary renal tumors in the rat: Cell lines from adenocarcinomas induced by the Eker mutation. Proc. Am. Assoc. Cancer Res., 51: 317, 1990.
41. DeLarco, J. E., and Todaro, G. J. Epithelioid and fibroblastic rat kidney cell clones: Epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation. J. Cell. Physiol., 94: 335-342, 1978.
42. Gaush, C. R., Hard, W. L., and Smith, T. F. Characterization of an established line of canine kidney cells (MDCK). Proc. Soc. Exp. Biol. Med., 122: 931-935, 1966.
43. Hull, R. N., Chery, W. R., and Weaver, G. W. The origin and characteristics of a pig kidney cell strain, LLC-PK,. In Vitro (Rockville), 12: 670-677, 1976.
44. Topp, W. C. Normal rat cell lines deficient in nuclear thymidine kinase. Virology, 775:408-411, 1981.
45. Loury, D. J., Smith-Olver, T., and Butterworth, B. E. Assessment of unscheduled DNA synthesis and cell replication in rat kidney cells exposed in vitro or in vivo to unleaded gasoline. Toxicol. Appl. Pharmacol., 87: 172, 1987.
46. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonucleases. Biochemistry, 18: 5294-5299, 1979.
47. Aviv, H., and Leder, P. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc. Natl. Acad. Sci. USA, 69:1408-1412, 1972.
48. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (eds.). Current Protocols in Molecular Biology. New York: John Wiley & Sons, 1989.
49. Scott, J., Urdea, M., Quiroga, M., Sanchez-Pescador, R., Fong, N., Selby, M., Rutter, W. J., and Bell, G. I. Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins. Science (Washington DC), 221: 236-240, 1983.
50. Earp, H. S., Hepler, J. R., Petch, L. A., Miller, A., Berry, A. R., Harris, J., Raymond, V. W., McCune, B. K., Lee, L. W., Grisham, J. W., and Harden, T. K. Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. J. Biol. Chem., 265: 13868-13874, 1988.
51. Gunning, P., Ponte, P., Okayama, H., Engel, J., Blau, H., and Kedes, L. Isolation and characterization of full-length cDNA clones for human a-, /9-, and 7-actin mRNAs: Skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed. Mol. Cell. Biol., 5: 787-795, 1983.
52. Stewart, W., and Walker, C. Comparison of nylon membranes. Methods Mol. Cell. Biol., 7:73-76, 1989.
53. Anzano, M. A., Rieman, D., Prichett, W., Bowen-Pope, D. F., and Greig, R. Growth factor production by human colon carcinoma lines. Cancer Res., 49: 2898-2904, 1989.
54. Short, B. G., Burnett, V. L., Cox, M. G., Bus, J. S., and Swenberg, J. A. Site-specific renal cytotoxicity and cell proliferation in male rats exposed to petroleum hydrocarbons. Lab. Invest., 57:564-577, 1987.
55. Hard, G. C. Experimental models for the sequential analysis of chemically-induced renal carcinogenesis. Toxicol. Pathol., 14: 112-122, 1986.
56. Poulsen, S. S., Nexo, E., Olsen, P. S., Hess, J., and Klrkegaard, P. Immunohistochemical localization of epidermal growth factor in rat and man. Histochemistry, 85:389-394,1986.
57. Lau, J. L. T., Fowler, J. E., and Ghosh, L. Epidermal growth factor in the normal and neoplastic kidney and bladder. J. Urol., 159: 170-175,1988.
58. Rail, L. B., Scott, J., Bell, G. I., Crawford, R. J., Penschow, J. D., Niall, H. D., and Coghlan, J. P. Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues. Nature (Lond.), 515: 228-231,1985.
59. Finch, P. W., Rubin, J. S., Miki, T., Ron, D., and Aaronson, S. A. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science (Washington DC), 245: 752-755,1989.
60. Safirstein, R., Zelent, A. Z., and Price, P. M. Reduced renal prepro-epidermal growth factor mRNA and decreased EGF excretion in ARF. Kidney Int., 56: 810-815,1989.
61. Maratos-Flier, E., Kao, C-Y. Y., Verdin, E. M., and King, G. L. Receptor-mediated vectorial transcytosis of epidermal growth factor by Madin-Darby canine kidney cells. J. Cell Biol., 105: 1595-1600, 1987.